K. Sridhar
SRM University
Composite numberBiophysicsElectrospinningGlycosaminoglycanMatrix (biology)Automotive engineeringChemistryEpigallocatechin gallateDrug deliveryPolycaprolactoneCartilagePolylactic acidChondrogenesisChemical engineeringCrystallinityTissue engineeringPorosityBovine serum albuminScaffoldNanofiber
Publications 5
#1Shitanshu Devrani (Chalmers University of Technology)
#2Rahul Kumar Tiwari (SRM University)
Last. K. Sridhar (SRM Medical College Hospital and Research Centre)H-Index: 1
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Abstract Being thermosensitive, Vaccines need storage at specific temperatures of 2-8 °C, and Vaccine Cold chain Carriers are the most widely utilized instruments to carry out rural vaccination drives in Low-income hot climate countries. Several developed designs for the carrier have reported superior performance, but their actual penetration into rural community medicine is limited due to reasons of cost and utility. Thus, the scope for improvement in the design is significant and it is also pe...
#2Subha Krishna RaoH-Index: 2
Last. S. Shantanu PatilH-Index: 1
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Abstract The therapeutic potential of an engineered cartilage construct can be enhanced by sustained delivery of chondrogenic drug like melatonin from 3D porous scaffolds embedded with melatonin loaded bovine serum albumin nanoparticles (MNP). In this study, MNP was synthesized and loaded into polycaprolactone (PCL) scaffolds. 12 % (w/v) and 10 % (w/v) PCL scaffolds were fabricated with different concentrations of MNP. X- ray diffraction and Raman analysis of MNP and scaffolds revealed amorphiza...
1 CitationsSource
#2K. SridharH-Index: 1
Last. S. Shantanu PatilH-Index: 1
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Abstract Epigallocatechin-3-gallate (EGCG), a plant polyphenol catechin is potent chondrogenic drug which enhances cartilage regeneration. Hence, sustained release of EGCG from interlinked porous polycaprolactone (PCL) scaffolds can be beneficial in engineering a cartilage construct. In this study, 10% (w/v) and 12% (w/v) PCL scaffold were fabricated by incorporation of 2 different concentrations (1 mg/ml & 2 mg/ml) of EGCG loaded albumin nanoparticles (ENP). Morphological analysis of the fabric...
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