Jin He
Johns Hopkins University School of Medicine
CancerInternal medicineRadiologySurgeryPathologyOncologyResectionRetrospective cohort studyCarcinomaPancreatectomyPancreasPancreaticoduodenectomyPancreatic cancerAdenocarcinomaPancreatic ductal adenocarcinomaIn patientCancer researchGeneral surgeryMedicineCohortGastroenterology
307Publications
40H-index
5,027Citations
Publications 307
Newest
#1Georgios Gemenetzis (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 17
#2Alex B. Blair (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 17
Last. Matthew J. Weiss (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 48
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BACKGROUND The introduction of multi-agent chemotherapy and radiation therapy has facilitated potential resection with curative intent in selected locally advanced pancreatic cancer (LAPC) patients with excellent outcomes. Nevertheless, there remains a remarkable lack of consensus on the management of LAPC. We sought to describe the outcomes of patients with LAPC and objectively define the multidisciplinary selection process for operative exploration based on anatomical factors. METHODS Consecut...
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#1Won Jin Ho (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 10
#2Qingfeng Zhu (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 13
Last. Nicole Gross (JHUSOM: Johns Hopkins University School of Medicine)
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A potentially curative hepatic resection is the optimal treatment for hepatocellular carcinoma (HCC) but most patients are not candidates for resection and most resected HCCs eventually recur. Until recently, neoadjuvant systemic therapy for HCC has been limited by a lack of effective systemic agents. Here, in a single-arm phase 1b study, we evaluated the feasibility of neoadjuvant cabozantinib and nivolumab in patients with HCC, including patients outside of traditional resection criteria (Clin...
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#1Manisha H. Shah (OSU: Ohio State University)H-Index: 58
#2Whitney S. GoldnerH-Index: 18
Last. Paul T. Fanta (UCSD: University of California, San Diego)H-Index: 24
view all 36 authors...
The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Neuroendocrine and Adrenal Gland Tumors focus on the diagnosis, treatment, and management of patients with neuroendocrine tumors (NETs), adrenal tumors, pheochromocytomas, paragangliomas, and multiple endocrine neoplasia. NETs are generally subclassified by site of origin, stage, and histologic characteristics. Appropriate diagnosis and treatment of NETs often involves collaboration between specialists in multiple discipline...
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#1Min Wang (HUST: Huazhong University of Science and Technology)H-Index: 32
#2Ding Ding (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 51
Last. Chien-Hui Wu (NTU: National Taiwan University)
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Abstract null null AJCC TNM stage and WHO grade (G) are two widely used staging systems to guide clinical management for pancreatic neuroendocrine neoplasms (panNENs), based on clinical staging and pathological grading information, respectively. We proposed to integrate TNM stage and G grade into one staging system (TNMG) and to evaluate its clinical application as a prognostic indicator for panNENs. Accordingly, 5254 patients diagnosed with panNENs were used to evaluate and to validate the appl...
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#1Benedict Kinny-Köster (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 3
#2Joseph R. Habib (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 6
Last. Jin He (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 40
view all 10 authors...
Purpose null The resection of retropancreatic nerve plexuses for pancreatic head cancer became standard of care during open pancreatoduodenectomy to minimize local recurrences. Since more surgical centers are progressing on the learning curve, robotically-assisted pancreatoduodenectomy is now increasingly performed with decreasing anatomic exclusion criteria. To achieve comparable and favorable oncologic outcomes, advanced surgical techniques should be transferred and implemented when performing...
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#1Joseph R. Habib (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 6
#2Yayun Zhu (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 1
Last. William H. Burns (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 20
view all 14 authors...
Background or purpose null Pancreatic ductal adenocarcinoma (PDAC) is commonly diagnosed by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). However, the diagnostic adequacy of EUS-FNA is often limited by low cellularity leading to inconclusive results. We aimed to investigate the feasibility and added utility of targeted next-generation sequencing (NGS) on PDAC EUS-FNAs. null Methods null EUS-FNAs were prospectively performed on 59 patients with suspected PDAC (2014-2017) at a hig...
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#1Joseph R. Habib (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 6
#2Shamsher Pasha (JHUSOM: Johns Hopkins University School of Medicine)
Last. William R. Burns (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 6
view all 16 authors...
Pancreatic ductal adenocarcinoma (PDAC) has a high propensity for systemic dissemination. Ovarian metastases are rare and poorly described. We identified PDAC cases with ovarian metastasis from a prospectively maintained registry. We reported on the association between outcomes and clinicopathologic factors. Recurrence-free (RFS) and overall survival (OS) were calculated using Kaplan–Meier analysis. Twelve patients with PDAC and synchronous or metachronous ovarian metastases were identified. Nin...
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#1A. Floortje van Oosten (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 3
#2Ding Ding (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 51
Last. Jin He (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 40
view all 16 authors...
INTRODUCTION Robotic pancreaticoduodenectomy is slowly gaining acceptance within pancreatic surgery. Advantages have been demonstrated for robotic surgery in other fields, but robust data for pancreaticoduodenectomy is limited. The aim of this study was to compare the short-term outcomes of robotic pancreaticoduodenectomy (RPD) to open pancreaticoduodenectomy (OPD) and laparoscopic pancreaticoduodenectomy (LPD). METHODS Patients who underwent a pancreaticoduodenectomy between January 2011 and Ju...
1 CitationsSource
#1Giovanni Marchegiani (University of Verona)H-Index: 29
#2Tommaso Pollini (University of Verona)H-Index: 8
Last. Roberto Salvia (University of Verona)H-Index: 52
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Importance The progression of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas to malignant disease is still poorly understood. Observational and surgical series have failed to provide comprehensive information. Objective To identify dynamic variables associated with the development of malignant neoplasms by combining pathological features with data from preoperative repeated observations. Design, Setting, and Participants The Crossover Observational Multicentric Study included a...
1 CitationsSource
#1Alex B. Blair (Johns Hopkins University)H-Index: 17
#2Lingdi Yin (Johns Hopkins University)H-Index: 5
Last. Jin He (Johns Hopkins University)H-Index: 40
view all 13 authors...
OBJECTIVE: The aim of this study was to characterize the patterns and treatment of disease recurrence in patients achieving a pathological complete response (pCR) following neoadjuvant chemoradiation for advanced pancreatic ductal adenocarcinoma (PDAC). SUMMARY OF BACKGROUND DATA: A pCR is an independent predictor for improved survival in PDAC. However, disease recurrence is still observed in these patients. METHODS: Patients with advanced PDAC who were treated with neoadjuvant therapy and had a...
6 CitationsSource