Zhifang Zheng
Southern Medical University
H&E stainUrologyEndocrinologySurgeryImmunohistochemistryEpidermal growth factorVaginal atrophyVascular endothelial growth factorBotulinum toxinDiabetic footPropranololCD31SympathectomyWound healingAngiogenesisSacrococcygeal RegionAnesthesiaMedicineStainingPharmacology
13Publications
3H-index
28Citations
Publications 13
Newest
#1Zhifang Zheng (Southern Medical University)H-Index: 3
#2Xiaoxuan LeiH-Index: 1
Last. Wenhua Huang (Southern Medical University)H-Index: 23
view all 6 authors...
BACKGROUND Cross-linked hyaluronic acid (HA) is an active anti-ageing cosmetic filler. The combination of cross-linked HA and preadipocytes or adipose-derived stem cells has been previously investigated, but the effects of agglomerated cross-linked HA injection on the vascularization of fat grafts remain unclear. OBJECTIVES To explore the effects of agglomerated cross-linked HA injection on the vascularization of fat grafts. METHODS The back of each nude mouse was divided into four regions that ...
1 CitationsSource
#1Zhifang Zheng (Southern Medical University)H-Index: 3
Last. Wenhua Huang (Southern Medical University)H-Index: 23
view all 6 authors...
BACKGROUND East Asian faces vary in shape but only oval faces seem to be considered attractive. Many patients with wide faces seek removal of part of the mandibular angle and/or zygoma to achieve an ideal facial contour, but the procedure is high risk and the recovery period is relatively protracted. OBJECTIVES We sought to achieve ideal facial contours through the use of autologous fat grafting (AFG) combined with masseter botulinum toxin (BTX) injection for patients with wide faces and massete...
Source
#1Zhifang Zheng (Southern Medical University)H-Index: 3
#2Junfeiyang Yin (Southern Medical University)
Last. Wenhua Huang (Southern Medical University)H-Index: 23
view all 4 authors...
Vaginal atrophy caused by the aging process and perineal trauma has a negative impact on women. A new vaginal atrophy treatment is injection of materials into the vaginal wall, including platelet-rich plasma (PRP), autogenous fat graft (AFG), hyaluronic acid (HA), botulinum toxin (BTX), and collagen, but to date their efficacy has not been reviewed. Vaginal wall injection is available only for mild cases of vaginal atrophy or as an adjunct to vaginal surgery. PRP is used mainly to restore vagina...
Source
#1Zhifang Zheng (Southern Medical University)H-Index: 3
#2Yishu Liu (Third Military Medical University)H-Index: 3
Last. Biao Cheng (Third Military Medical University)H-Index: 5
view all 7 authors...
AbstractDiabetic foot ulcers (DFUs) are a threat to human health and can lead to amputation and even death. Recently neurotensin (NT), an inflammatory modulator in wound healing, was found to be beneficial for diabetic wound healing. As we demonstrated previously, polylactide–polyglycolide (PLGA) and cellulose nanocrystals (CNCs) (PLGA/CNC) nanofiber membranes show good cytocompatibility and facilitate fibroblast adhesion, spreading and proliferation. PLGA/CNC nanofiber membranes are novel mater...
10 CitationsSource
目的: 探讨采用新型前置式脂肪抽吸针抽取脂肪对移植后脂肪成活的影响。. Methods: Two groups of fats were obtained from the left and right sides of a female patient during the abdomen liposuction surgery, respectively. And the fats in experimental group and control group were harvested by the new front opening liposuction cannula and the side hole liposuction cannula, respectively. The differences of adipocyte activity in vitro between 2 groups were compared by observation under the electron scanning microscopy and the glucose tran...
Source
#1Zhifang Zheng (Southern Medical University)H-Index: 3
#2Yishu Liu (Third Military Medical University)H-Index: 3
Last. Biao ChengH-Index: 5
view all 6 authors...
BACKGROUND: The effect of lumbar sympathectomy for the treatment of lower limb ischemia remains a matter of controversy. METHODS: Sprague-Dawley rats were subjected to lumbar sympathectomy, after which Evans blue dye was injected into the hind plantar skin. Extravasation of dye was measured and compared with rats undergoing sham operation. Hind plantar skin was processed for HE staining, immunohistochemistry, and Western blot. RESULTS: In sympathectomized rats, blue stained areas in hind plantar...
4 CitationsSource
#1Zhifang Zheng (Southern Medical University)H-Index: 3
#2Yu Wan (Southern Medical University)H-Index: 1
Last. Biao ChengH-Index: 5
view all 7 authors...
Previous studies focused on the effects of sympathetic denervation with 6-hydroxydopamine (6-OHDA) on nondiabetic wounds, but the effects of 6-OHDA on diabetic wounds have not been previously reported. In this study, treated mice received intraperitoneal 6-OHDA, and control mice received intraperitoneal injections of normal saline. Full-thickness wounds were established on the backs of mice. The wounds were sectioned (four mice per group) for analysis at 2, 5, 7, 10, 14, 17, and 21 days after in...
2 CitationsSource
#1Zhifang Zheng (Southern Medical University)H-Index: 3
#2Yishu Liu (Third Military Medical University)H-Index: 3
Last. Biao Cheng (Third Military Medical University)H-Index: 5
view all 6 authors...
Local sympathetic denervation by surgical sympathectomy is used in the treatment of lower limb ulcers and ischemia, but the restoration of cutaneous sympathetic nerve functions is less clear. This study aims to explore the recovery of cutaneous sympathetic functions after bilateral L2-4 sympathectomy. The skin temperature of the left feet, using a point monitoring thermometer, increased intraoperatively after sympathectomy. The cytoplasm of sympathetic neurons contained tyrosine hydroxylase and ...
Source
#1Zhifang Zheng (Southern Medical University)H-Index: 3
#2Yi-shu LiuH-Index: 1
Last. Biao Cheng (Southern Medical University)H-Index: 1
view all 5 authors...
Diabetic foot ulcers (DFUs) are a constant threat to diabetic patients and can lead to amputations and even death. Intralesional administration of propranolol in diabetic wounds has not been reported previously. This study aimed to investigate the efficacy of propranolol cream in diabetic wounds. Fifty-six spontaneously diabetic mice were divided into the propranolol group and the control group. After preparing full-thickness wounds on the back of the mice, 1% propranolol cream was topically app...
7 CitationsSource
#1Zhifang ZhengH-Index: 3
#2Yishu LiuH-Index: 3
Last. Biao ChengH-Index: 1
view all 3 authors...
Sympathetic denervation is associated with many diseases. Most cutaneous external monitoring indicators are non-invasive and used widely in clinical medicine. The external monitoring indicators of sympathetic denervation are reviewed to facilitate the clinical diagnosis of sympathetic diseases and the results of sympathectomy. Useful indicators of sympathetic denervation include sweating, warm skin, increased blood flow, Electrodermal Activity (EDA), pain response, skin integrity, and skin wrink...
1 Citations