Robert K. Darragh
Indiana University
Internal medicineSurgeryCardiologyFetusIntensive care medicineGreat arteriesDilated cardiomyopathyFontan procedureVascular surgeryCardiac surgeryCardiomyopathyHeart transplantationBronchoscopyAutopsyHypoplastic left heart syndromeHeart diseasePulmonary arteryPopulationTransplantationMedicineComplication
16Publications
7H-index
335Citations
Publications 15
Newest
#1Nicholas B. Zaban (IU: Indiana University)H-Index: 1
#2Robert K. Darragh (IU: Indiana University)H-Index: 7
Last. John J. Parent (IU: Indiana University)H-Index: 6
view all 3 authors...
We screened all fetal echocardiograms performed at our institution for the past 5 years for the indication of family history of cardiomyopathy. Twenty-six patients were identified who had fetal echocardiograms performed due to a family history of cardiomyopathy. Three out of 26 patients (11.5%) had findings of decreased ventricular function and dilation consistent with cardiomyopathy. All who had cardiomyopathy on fetal echocardiography had parents with genetic mutations (2 maternal, 1 paternal)...
Source
#1Adam C. Kean (IU: Indiana University)H-Index: 3
#2Benjamin M. Helm (IU: Indiana University)H-Index: 7
Last. Robert K. Darragh (IU: Indiana University)H-Index: 7
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Introduction: The SCN5A gene is implicated in many arrhythmogenic and cardiomyopathic processes. We identified a novel SCN5A variant in a family with significant segregation in individuals affected with progressive sinus and atrioventricular nodal disease, atrial arrhythmia, dilated cardiomyopathy, and early sudden cardiac arrest. Methods: A patient pedigree was created following the clinical evaluation of three affected individuals, two monozygotic twins and a paternal half-brother, which lead ...
2 CitationsSource
1 CitationsSource
#1John J. Parent (IU: Indiana University)H-Index: 6
#2Robert K. Darragh (IU: Indiana University)H-Index: 7
Last. Clifford Chin (Cincinnati Children's Hospital Medical Center)H-Index: 11
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Plastic bronchitis, a rare complication after Fontan palliation, carries a high morbidity and mortality risk. Heart transplantation is an effective treatment option, but casts may occur in the early post-operative period. We present a case series detailing peri-operative management strategies to minimize morbidity and mortality related to plastic bronchitis in patients undergoing heart transplantation. Patient 1 received no treatment pre-, intra-, or post-transplant for prevention of bronchial c...
6 CitationsSource
#1John J. Parent (IU: Indiana University)H-Index: 6
#2Lauren E. Sterrett (IU: Indiana University)H-Index: 5
Last. Eric S. Ebenroth (IU: Indiana University)H-Index: 12
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John J. Parent , Lauren Sterrett, Randall Caldwell, Robert Darragh, Marcus Schamberger, Debbie Murphy,Eric EbenrothDepartment of Pediatric Cardiology, Indiana University School of Medicine, Indianapolis, United States of AmericaAbstract Background: We evaluated whether quality of life correlates to age and activity in children following hearttransplantation. In addition, quality of life in children following heart transplantation was compared with previouslyreported values in children with conge...
5 CitationsSource
#1John J. Parent (IU: Indiana University)H-Index: 6
#2Robert K. Darragh (IU: Indiana University)H-Index: 7
Plastic bronchitis is a rare and difficult to treat disease process in patients with congenital heart disease. Cardiac transplantation has been used increasingly to reverse this process, especially in single ventricle physiology. This case report demonstrates a foreseeable complication after cardiac transplantation in such a patient.
3 CitationsSource
#1Matthew T. Bramlet (IU: Indiana University)H-Index: 2
#2Ryan Moore (IU: Indiana University)H-Index: 1
Last. Marcus S. Schamberger (IU: Indiana University)H-Index: 11
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Background. Several studies have demonstrated the utility of B-type natriuretic peptide (BNP) in the months following cardiac transplant. The purpose of this study was to analyze longitudinal BNP data in pediatric cardiac transplant patients and determine the efficacy of BNP in routine follow-up of transplant to help predict the adverse event of death or re-transplant. Methods. From October 2002 to July 2007, 53 pediatric cardiac transplant patients were treated in an unmatched case-control stud...
5 CitationsSource
#1John W. Brown (IU: Indiana University)H-Index: 69
#2Mark Ruzmetov (IU: Indiana University)H-Index: 29
Last. Robert K. Darragh (IU: Indiana University)H-Index: 7
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Background Pulmonary homografts (PH) have been the preferred valved conduits for right ventricular outflow tract (RVOT) reconstruction in the US since the mid-1980s. Although PHs have worked well for Ross patients, many PH extracardiac conduits used for congenital heart surgery suffer from degeneration and develop regurgitation and obstruction within months after implantation and require replacement within 4 to 6 years. Recently a valve-containing bovine jugular vein (Contegra, Medtronic, Inc, M...
135 CitationsSource
#1Linda S. Williams (IU: Indiana University)H-Index: 59
#2Robert K. Darragh (IU: Indiana University)H-Index: 7
Last. Mark W. Turrentine (IU: Indiana University)H-Index: 53
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Reversible posterior leukoencephalopathy syndrome (RPLES), previously known as posterior reversible encephalopathy syndrome (PRES), is characterized by the presence of bilateral lesions located within the posterior border zones of the cerebral hemisphere and cerebellum. This condition commonly presents with headache, nausea, vomiting, decreased vision and level of consciousness, and seizures. RPLES has been associated with hypertensive encephalopathy, eclampsia, renal failure, and immunosuppress...
6 CitationsSource
#1Eric S. Ebenroth (IU: Indiana University)H-Index: 12
#2Timothy M. Cordes (IU: Indiana University)H-Index: 11
Last. Robert K. Darragh (IU: Indiana University)H-Index: 7
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Digoxin has been an effective treatment for fetal supraventricular tachycardia (SVT), but second-line therapy remains more controversial. Thirty-seven cases of fetal SVT were identified that received digoxin as first-line therapy. Seventeen fetuses (46%) converted to and maintained normal sinus rhythm. Flecainide was used in 13/15 patients requiring second-line therapy; 12/13 (92%) converted to sinus rhythm. Of seven hydropic fetuses, five required second-line therapy and were then successfully ...
67 CitationsSource