Xin Zhao
Shanghai Jiao Tong University
Self-healing hydrogelsBiophysicsBiomedical engineeringSurgeryNanoparticleNanotechnologyChemistryMaterials scienceIn vivoDrug deliveryPhotocurrentWater splittingChemical engineeringOptoelectronicsTissue engineeringCancer researchPolymerDopingMedicineAdhesion
Publications 235
#1Han Yu (Southwest Jiaotong University)H-Index: 3
#2Shaoxing Yu (Southwest Jiaotong University)H-Index: 1
Last. Zhilu Yang (Southwest Jiaotong University)H-Index: 26
view all 12 authors...
Abstract Application of extracorporeal circuits and indwelling medical devices has saved many lives. However, it is accompanied with two major complications: thrombosis and infection. To address this issue, we apply therapeutic nitric oxide gas (NO) and antibacterial peptide for synergistically tailoring such devices for surface anti-thrombogenic and antifouling dual functions. Such functional surface is realized by stepwise conjugation of NO-generating compound of 1,4,7,10-tetraazacyclododecane...
#1Xinghua Wu (GDUT: Guangdong University of Technology)H-Index: 13
#2Fan Yang (NTU: Nanyang Technological University)H-Index: 2
Last. Shunzhi Qian (NTU: Nanyang Technological University)H-Index: 1
view all 6 authors...
Abstract Condensation poses a serious challenge to the mechanical durability and sustainable development of modern buildings in tropical environment. Moisture condensation and absorption in architecture causes inconvenience and requires extra maintenance measures. A mechanically durable anti-condensation coating that displays very low affinity with moisture is promising for applications on wall and ceiling of buildings. A main challenge in the fabrication of anti-condensation surface lies with t...
1 CitationsSource
A toroidal soft x-ray array system for spectrum and intensity measurements on the EXL-50 spherical tokamak is described. Silicon drift detectors and digital multichannel analyzers are adopted for all 21 channels of the array, and an average energy resolution of 147 eV at 5.89 keV has been achieved at count rates over 500 kcps. In total, 20 channels of the array are symmetrically observed in both co- and counter-current directions on the EXL-50 mid-plane with a spatial resolution of around 10 cm,...
#1Wenxuan Wang (Southwest Jiaotong University)H-Index: 1
#2Lei Lu (Southwest Jiaotong University)H-Index: 4
Last. Zhilu Yang (Southwest Jiaotong University)H-Index: 26
view all 10 authors...
Abstract Blood-contacting devices have emerged in the 21st century as the go-to clinical treatment for severe cardiovascular diseases. Due to their poor hemocompatibility, many coatings have been developed to improve their biocompatibility with limited success due to the lack of robustness in biomolecule conjugation. In this paper, we propose a new self-protonating, plasma polymerized, superimposed multi-layered nanoreservoir coating for immobilization of charged biomolecules, and demonstrated i...
#1Yue Ma (Jiangsu University)H-Index: 33
#2Peiyan He (Jiangsu University)H-Index: 1
Last. Guoqing Pan (Jiangsu University)H-Index: 33
view all 9 authors...
Simulation of self-recovery and diversity of natural photonic crystal (PC) structures remain great challenges for artificial PC materials. Motivated by the dynamic characteristics of PC nanostructures, here, we present a new strategy for the design of hydrogel-based artificial PC materials with reversible interactions in the periodic nanostructures. The dynamic PC hydrogels, derived from self-assembled microgel colloidal crystals, were tactfully constructed by reversible crosslinking of adjacent...
#1Yuhe Yang (PolyU: Hong Kong Polytechnic University)H-Index: 4
#2Tianpeng Xu (PolyU: Hong Kong Polytechnic University)H-Index: 1
Last. Xin Zhao (PolyU: Hong Kong Polytechnic University)H-Index: 45
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Current periosteal grafts have limitations related to low mechanical strength, tissue adhesiveness, and poor osteogenesis and angiogenesis potential. Here, a periosteum mimicking bone aid (PMBA) with similar structure and function to natural periosteum is developed by electrospinning photocrosslinkable methacrylated gelatin (GelMA), l-arginine-based unsaturated poly(ester amide) (Arg-UPEA), and methacrylated hydroxyapatite nanoparticles (nHAMA). Such combination of materials enhances the materia...
#1Hong Yang (Xi'an Jiaotong University)H-Index: 98
#1Hui YangH-Index: 2
Last. Hong Wang (Xi'an Jiaotong University)H-Index: 126
view all 6 authors...
The recent COVID-19 pandemic poses a global health emergency. Cellular entry of the causative agent SARS-CoV-2 is mediated by its spike protein interacting with cellular receptor- human angiotensin converting enzyme 2 (ACE2). Here, we used lentivirus based pseudotypes bearing spike protein to demonstrate that entry of SARS-CoV-2 into host cells is dependent on clathrin-mediated endocytosis, and phosphoinositides play essential role during this process. In addition, we showed that the intracellul...
#1Liling Zhang (Nantong University)H-Index: 3
#2Qi Han (Nantong University)H-Index: 2
Last. Yumin Yang (Nantong University)H-Index: 29
view all 8 authors...
Abstract Mechanical property is an important factor of cellular microenvironment for neural tissue regeneration. In this study, polyacrylamide (PAM) hydrogels with systematically varying elastic modulus were prepared using in situ radical polymerization. We found that the hydrogel was biocompatible, and the length of dorsal root ganglion (DRG)'s axon and cell density were optimal on the hydrogels with elastic modulus of 5.1 kPa (among hydrogels with elastic modulus between 3.6 kPa and 16.5 kPa)....
#1Zhuoyue Chen (Northwest University (United States))H-Index: 2
#1Zhuoyue Chen (Northwest University (China))H-Index: 17
Last. Fulin Chen (Northwest University (United States))H-Index: 9
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Silk fibroin (SF) is considered biocompatible and biodegradable for osteochondral repair. However, it lacks a bioactive domain for cell adhesion, proliferation and differentiation, limiting its therapeutic efficacy. To revamp SF as a biomimicking and bioactive microenvironment to regulate cell behaviours, we engineered an elastin-like polypeptide (ELP, Val-Pro-Gly-Xaa-Gly) to modify SF fibers via simple and green dehydrothermal (DHT) treatment. Our results demonstrated that the ELP successfully ...
4 CitationsSource
#2Dongbao LiH-Index: 3
Last. Xin ZhaoH-Index: 45
view all 7 authors...