David Gibbons
University College Dublin
Internal medicineRadiologySurgeryPathologyOncologyRetrospective cohort studyStage (cooking)CytologyImmunohistochemistryHazard ratioPathologicalDysplasiaBiopsyFine-needle aspirationDyskaryosisCarcinomaNeoadjuvant therapyChemoradiotherapyCytopathologyDiseaseTumor buddingLymph nodeAdenocarcinomaPopulationGynecologyColorectal cancerMedicineBiologyGastroenterology
Publications 62
Endometrial mesonephric-like carcinoma (ML-CA) is a recently recognized subtype of aggressive endometrial adenocarcinoma that is morphologically and immunophenotypically similar to mesonephric carcinoma but not typically associated with mesonephric remnants. Here, we report a case of 58-yr-old female who had a past medical history of fibroids and of irregular menstrual bleeding for ~20 yr who presented with visual disturbance. On further investigation, she was found to have a large choroidal per...
#1Tariq Sami Haddad (Radboud University Nijmegen)H-Index: 1
#2Alessandro Lugli (University of Bern)H-Index: 70
Last. Iris D. Nagtegaal (Radboud University Nijmegen)H-Index: 85
view all 26 authors...
Tumor budding is a long-established independent adverse prognostic marker in colorectal cancer, yet methods for its assessment have varied widely. In an effort to standardize its reporting, a group of experts met in Bern, Switzerland, in 2016 to reach consensus on a single, international, evidence-based method for tumor budding assessment and reporting (International Tumor Budding Consensus Conference [ITBCC]). Tumor budding assessment using the ITBCC criteria has been validated in large cohorts...
#2Cormac O'Brien (UCD: University College Dublin)H-Index: 2
Last. David GibbonsH-Index: 19
view all 8 authors...
#1Dorinda MullenH-Index: 2
#2David Gibbons (UCD: University College Dublin)H-Index: 19
BACKGROUND: Fine needle aspiration (FNA) is a routine sampling method in the diagnostic work up of salivary gland lesions. Despite universal use, no standardised classification existed for the cytopathological reporting of such entities until recently. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) aims to standardise the reporting of these lesions, offering risk of malignancy rates and clinical management recommendations. METHODS: We retrospectively applied MSRSGC to cases...
#1Ciara Ellen Gibbons (Mater Misericordiae University Hospital)H-Index: 1
#2Cecily Quinn (UCD: University College Dublin)H-Index: 28
Last. David Gibbons (UCD: University College Dublin)H-Index: 19
view all 3 authors...
CONTEXT: Fine-needle aspiration biopsy (FNAB) is frequently used to stage the axilla preoperatively in patients with primary breast carcinoma. In the light of the ACOSOG-Z0011 and AMAROS trials that specified sentinel lymph node biopsy as an inclusion criterion, the role of FNAB in axillary staging is changing. OBJECTIVE: This article will review the diagnostic accuracy of FNAB in staging of the axilla in patients with primary breast carcinoma. The efficacy of axillary FNAB compared with core-ne...
#1Éanna J. RyanH-Index: 12
#2Ben CreavinH-Index: 13
Last. Des C. WinterH-Index: 26
view all 15 authors...
Background: Caudal-related homeobox transcription factor 2 (CDX2) is an intestine-specific transcription factor implicated in tumour differentiation, proliferation, cell adhesion and migration. Negative CDX2 status (CDX2-) is associated with worse prognosis in colorectal cancer and may identify high-risk stage II disease that benefits from adjuvant chemotherapy. This observational study investigated whether CDX2- is associated with prognosis or response to chemotherapy in the mismatch repair-def...
#1Ben CreavinH-Index: 13
#2Éanna J. RyanH-Index: 12
Last. Des C. WinterH-Index: 26
view all 6 authors...
#1Chwanrow BabanH-Index: 2
#2Maimoona AzharH-Index: 5
Last. R. S. PrichardH-Index: 14
view all 8 authors...
: Mismatch repair deficient (dMMR) colorectal cancer (CRC) despite its association with poor histologic grade often has improved prognosis compared with MMR proficient CRC. Tumor budding and poorly differentiated clusters (PDCs) may predict metastatic potential of colorectal adenocarcinoma (CRC). In addition, their assessment may be more reproducible than the evaluation of other histopathologic parameters. Therefore, we wished to determine their potential as prognostic indicators in a cohort of ...
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