Yu Ah Hong
Catholic University of Korea
Internal medicineEndocrinologyOdds ratioRenal functionCardiologyChemistryApoptosisImmunologyHazard ratioOxidative stressInflammationHemodialysisKidney diseasePeritoneal dialysisDialysisKidneyAMPKCreatinineAcute kidney injuryNephropathyIn patientMedicineGastroenterologyPharmacology
63Publications
12H-index
463Citations
Publications 63
Newest
#1Won Jung ChoiH-Index: 1
#2Yu Ah HongH-Index: 12
Last. Seok Young KimH-Index: 1
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IgA nephropathy (IgAN) is a globally well-known primary glomerular nephropathy. Hypertriglyceridemia (HTG) is one factor contributing to atherosclerosis and is a common complication of renal failure. HTG is a significant risk factor for decreased renal function in patients with IgAN. We evaluated the association of HTG with the histopathological features of IgAN patients. A total of 480 patients diagnosed with IgAN via kidney biopsy from eight university hospitals affiliated with the College of ...
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#1Yu Ah Hong (Catholic University of Korea)H-Index: 12
#2Ki Cheol Park (St Mary's Hospital)H-Index: 21
Last. Suk Young Kim (Catholic University of Korea)H-Index: 11
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Secondary hyperparathyroidism (SHPT) is characterized by excessive serum parathyroid hormone levels in response to decreasing kidney function, and tertiary hyperparathyroidism (THPT) is often the result of a long-standing SHPT. To date, several genes have been associated with the pathogenesis of primary hyperparathyroidism (PHPT). However, the molecular genetic mechanisms of uremic hyperparathyroidism (HPT) remain uncharacterized. To elucidate the differences in genetic alterations between PHPT ...
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#1Yu Ah Hong (Catholic University of Korea)H-Index: 12
#2Tae Hyun Ban (Catholic University of Korea)H-Index: 7
Last. Yong Kyun Kim (Catholic University of Korea)H-Index: 16
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Background The Korean Society of Nephrology (KSN) has maintained a nationwide end-stage renal disease (ESRD) registry data from Korean Renal Data System (KORDS) since 1985, as the representative registry of ESRD patients in Korea. This review is aimed to update the status of domestic ESRD and to provide evidence on the direction of dialysis therapy. Methods The KORDS Committee of KSN has collected data on dialysis centers and patients through an online registry program, and the data from 1986 to...
2 CitationsSource
#1Yu Ah Hong (Catholic University of Korea)H-Index: 12
#2Cheol Whee Park (Catholic University of Korea)H-Index: 32
Reactive oxygen species and reactive nitrogen species are highly implicated in kidney injuries that include acute kidney injury, chronic kidney disease, hypertensive nephropathy, and diabetic nephropathy. Therefore, antioxidant agents are promising therapeutic strategies for kidney diseases. Catalytic antioxidants are defined as small molecular mimics of antioxidant enzymes, such as superoxide dismutase, catalase, and glutathione peroxidase, and some of them function as potent detoxifiers of lip...
3 CitationsSource
#1Youngdong Jeon (Catholic University of Korea)
#2Hyung Duk Kim (Catholic University of Korea)H-Index: 3
Last. Yong Kyun Kim (Catholic University of Korea)H-Index: 16
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Background Infection is the second leading cause of death in patients undergoing long-term dialysis. Peritoneal dialysis (PD) is associated with an increased risk of infection-related hospitalization (IRH) when compared with hemodialysis. In this study, we investigated the influence of IRH on clinical outcomes in incident PD patients. Methods In total, 583 incident PD patients were selected from the Clinical Research Center Registry for End-Stage Renal Disease, a nationwide multicenter prospecti...
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#1Yu Ah Hong (Catholic University of Korea)H-Index: 12
#2Ji Eun Kim (KU: Korea University)H-Index: 4
Last. Gang-Jee Ko (KU: Korea University)H-Index: 1
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Sirtuins (SIRTs) are class III histone deacetylases (HDACs) that play important roles in aging and a wide range of cellular functions. Sirtuins are crucial to numerous biological processes, including proliferation, DNA repair, mitochondrial energy homeostasis, and antioxidant activity. Mammals have seven different sirtuins, SIRT1–7, and the diverse biological functions of each sirtuin are due to differences in subcellular localization, expression profiles, and cellular substrates. In this review...
5 CitationsSource
#1Yu Ah Hong (Catholic University of Korea)H-Index: 12
#2Ji Won Min (Catholic University of Korea)H-Index: 6
Last. Hye Eun Yoon (Catholic University of Korea)H-Index: 24
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Several studies reported the effect of obesity on the progression of IgA nephropathy (IgAN). However, the impact of obesity on the clinicopathologic presentation of IgAN remains uncertain. This is a retrospective cross-sectional study from eight university hospitals in South Korea. Patients were categorized into three groups using the Asia-Pacific obesity classification based on body mass index (BMI). Clinical and histopathologic data at the time of renal biopsy were analyzed. Among 537 patients...
4 CitationsSource
#1Yu Ah Hong (Catholic University of Korea)H-Index: 12
#2So Young Jung (St Mary's Hospital)H-Index: 3
Last. Hyeon Seok Hwang (Kyung Hee University)H-Index: 4
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Cilastatin is a specific inhibitor of renal dehydrodipeptidase-1. We investigated whether cilastatin preconditioning attenuates renal ischemia-reperfusion (IR) injury via hypoxia inducible factor-1α (HIF-1α) activation. Human proximal tubular cell line (HK-2) was exposed to ischemia, and male C57BL/6 mice were subjected to bilateral kidney ischemia and reperfusion. The effects of cilastatin preconditioning were investigated both in vitro and in vivo. In HK-2 cells, cilastatin upregulated HIF-1α ...
3 CitationsSource