Saiko Nishioka
Jikei University School of Medicine
Internal medicineRadiologyPathologyMutantPoint mutationIntensive care medicineProspective cohort studyAdverse effectObservational studyRespiratory diseaseRNA polymeraseCorticosteroidRespiratory failureSynovial sarcomaExacerbationEosinophilMechanical ventilationRenal cell carcinomaHigh-resolution computed tomographyPosterior reversible encephalopathy syndromerpoSCerebral amyloid angiopathyMepolizumabKidney diseaseIntubationMetastasisBenralizumabPleural effusionSingle CenterNephrectomyOxygen therapyIdiopathic bronchiectasisEosinophilic asthmaCoronavirus disease 2019 (COVID-19)Late phaseLife studyPleural metastasisLow doseTranscription (biology)AnesthesiaSigma factorAmino acidRespiratory systemComputed tomographyEscherichia coliBiochemistryTerm (time)MedicinePulmonary function testingBiologyMicrobiology
7Publications
2H-index
7Citations
Publications 7
Newest
Abstract We present a case of a 69-year-old man who had localized pleural metastasis without other organ metastases after nephrectomy for right renal cell carcinoma (RCC). He complained of respiratory symptoms for more than two years after the operation and was confirmed to have right pleural effusion and multiple pleural masses on computed tomography (CT). There were no abnormal findings in the other organs, but the pleural mass gradually increased in size on CT. We suspected malignant tumors s...
Source
#1Zenya SaitoH-Index: 5
#2Masahiro YoshidaH-Index: 42
Last. Kazuyoshi KuwanoH-Index: 58
view all 6 authors...
Source
#1Takanori Numata (Jikei University School of Medicine)H-Index: 17
#2Hanae Miyagawa (Jikei University School of Medicine)H-Index: 1
Last. Kazuyoshi Kuwano (Jikei University School of Medicine)H-Index: 58
view all 11 authors...
Benralizumab, an anti-interleukin-5 (IL-5) receptor α monoclonal antibody, significantly reduces the number of annual exacerbations and oral corticosteroid (OCS) maintenance doses for patients with severe eosinophilic asthma (SEA). However, few studies on the efficacy of this biologic in real life are available. The aim was to elucidate the efficacy of benralizumab by evaluating changes in clinical parameters after benralizumab treatment in patients with SEA. From July 2018 to December 2019, 24 ...
2 CitationsSource
#1Kentaro TamuraH-Index: 1
#2Saiko NishiokaH-Index: 2
Last. Kazuyoshi KuwanoH-Index: 58
view all 5 authors...
This is a first observational study of four patients on steroid pulse therapy for secondary organizing pneumonia with respiratory failure due to the Coronavirus Disease 2019 (COVID-19) in our hospital. All patients needed invasive mechanical ventilation and had bimodal worseness of their respiratory status with organizing pneumonia after intubation. All cases could successfully discontinue oxygen therapy without any severe adverse events after this pulse therapy. Although few previous reports sh...
Source
#1Kentaro Tamura (Jikei University School of Medicine)H-Index: 1
#2Saiko Nishioka (Jikei University School of Medicine)H-Index: 2
Last. Kazuyoshi Kuwano (Jikei University School of Medicine)H-Index: 58
view all 5 authors...
Although some prospective studies provided the evidence of corticosteroids for critically ill patients with COVID-19, the optimal dosage or timing of corticosteroids is still unknown. This is a case series of four patients on methyl-prednisolone pulses for the late phase of Coronavirus disease 2019 (COVID-19) with respiratory failure in our hospital. All patients needed invasive mechanical ventilation and had bimodal worseness of their respiratory status with consolidation and volume loss after ...
Source
#1Saiko Nishioka (Jikei University School of Medicine)H-Index: 2
#2Shohei Fukunaga (Jikei University School of Medicine)H-Index: 2
Last. Takashi Yokoo (Jikei University School of Medicine)H-Index: 26
view all 8 authors...
Source
#1Tadayuki Iwase (Jikei University School of Medicine)H-Index: 12
#2Takashi Matsuo (Nara Institute of Science and Technology)H-Index: 23
Last. Yoshimitsu Mizunoe (Jikei University School of Medicine)H-Index: 33
view all 5 authors...
RpoS is a key stress-inducible sigma factor that regulates stress resistance genes in Escherichia coli, such as the katE gene encoding catalase HPII and the glg genes encoding glycogen synthesis proteins. Monitoring RpoS activity can provide information on the stress sensitivity of E. coli isolates in clinical settings because the RpoS in these isolates is often mutated. In the present study, we found a novel, missense point mutation at RpoS residue 128 in a clinical Shiga toxin-producing E. col...
5 CitationsSource