Ben Busby
National Institutes of Health
RNA-SeqBinding siteWorld Wide WebGenomeMetagenomicsRefSeqWorkflowAnkyrinInformation retrievalData scienceAnnotationSoftwareObscurinComputer sciencePipeline (software)BiochemistryBioinformaticsComputational biologyMedicineBiology
59Publications
11H-index
319Citations
Publications 58
Newest
#1Ben BusbyH-Index: 11
#2Bhavya PapudeshiH-Index: 5
Last. Taylor O'ConnellH-Index: 3
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#1Ben BusbyH-Index: 11
#2Jan P. BuchmannH-Index: 15
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#1Ben BusbyH-Index: 11
#2Surya SahaH-Index: 16
Last. Joan Martí-CarrerasH-Index: 6
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1 CitationsSource
#1Ben BusbyH-Index: 11
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#1Hsinyi Tsang (NIH: National Institutes of Health)H-Index: 1
#2Matthew A. Moss (CSHL: Cold Spring Harbor Laboratory)H-Index: 1
Last. Ben Busby (NIH: National Institutes of Health)H-Index: 11
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Multidrug resistant bacteria are becoming a major threat to global public health. While there are many possible causes for this, there have so far been few adequate solutions to this problem. One of the major causes is a lack of clinical tools for efficient selection of an antibiotic in a reliable way. NastyBugs is a new program that can identify what type of antimicrobial resistance is most likely present in a metagenomic sample, which will allow for both smarter drug selection by clinicians an...
1 CitationsSource
#1Kieran O'NeillH-Index: 9
Last. Aly KarsanH-Index: 61
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#1Kishore R. Anekalla (NU: Northwestern University)H-Index: 8
#2Jean-Paul Courneya (UMB: University of Maryland, Baltimore)H-Index: 8
Last. Ben Busby (NIH: National Institutes of Health)H-Index: 11
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Biomedical text mining promises to assist biologists in quickly navigating the combined knowledge in their domain. This would allow improved understanding of the complex interactions within biological systems and faster hypothesis generation. New biomedical research articles are published daily and text mining tools are only as good as the corpus from which they work. Many text mining tools are underused because their results are static and do not reflect the constantly expanding knowledge in th...
4 CitationsSource
#1Eric M. Weitz (NIH: National Institutes of Health)H-Index: 1
#2Lorena Pantano (Harvard University)H-Index: 19
Last. Ben Busby (NIH: National Institutes of Health)H-Index: 11
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RNA-Seq Viewer is a web application that enables users to visualize genome-wide expression data from NCBI’s Sequence Read Archive (SRA) and Gene Expression Omnibus (GEO) databases. The application prototype was created by a small team during a three-day hackathon facilitated by NCBI at Brandeis University. The backend data pipeline was developed and deployed on a shared AWS EC2 instance. Source code is available at https://github.com/NCBI-Hackathons/rnaseqview .
2 CitationsSource
#1Igor Dolgalev (NYU: New York University)H-Index: 28
#2Fritz J. Sedlazeck (Johns Hopkins University)H-Index: 29
Last. Ben Busby (NIH: National Institutes of Health)H-Index: 11
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Over recent years, multiple groups have shown that a large number of structural variants, repeats, or problems with the underlying genome assembly have dramatic effects on the mapping, calling, and overall reliability of single nucleotide polymorphism calls. This project endeavored to develop an easy-to-use track for looking at structural variant and repeat regions. This track, DangerTrack, can be displayed alongside the existing Genome Reference Consortium assembly tracks to warn clinicians and...
8 CitationsSource
#1Erin K. WagnerH-Index: 9
#2Satyajeet Raje (NIH: National Institutes of Health)H-Index: 4
Last. Ben Busby (NIH: National Institutes of Health)H-Index: 11
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Data sharing is critical to advance genomic research by reducing the demand to collect new data by reusing and combining existing data and by promoting reproducible research. The Cancer Genome Atlas (TCGA) is a popular resource for individual-level genotype-phenotype cancer related data. The Database of Genotypes and Phenotypes (dbGaP) contains many datasets similar to those in TCGA. We have created a software pipeline that will allow researchers to discover relevant genomic data from dbGaP, bas...
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