Renaud de Crevoisier
University of Rennes
CancerInternal medicineRadiologyUrologySurgeryMagnetic resonance imagingOncologyArtificial intelligenceImage registrationPattern recognitionProstateProstate cancerRectumPopulationNuclear medicineComputer visionComputer scienceRadiation therapyMedicineImage-guided radiation therapy
138Publications
28H-index
2,670Citations
Publications 137
Newest
#1Richard Rios (French Institute of Health and Medical Research)
#2Frederic Commandeur (French Institute of Health and Medical Research)H-Index: 13
Last. Renaud de Crevoisier (French Institute of Health and Medical Research)H-Index: 28
view all 6 authors...
In radiotherapy for prostate cancer the bladder presents the largest inter-fraction shape variations during treatment resulting in random geometric uncertainties that may increase the risk of developing side-effects. In this setting, our interest is thus to propose a hierarchical population model, based on longitudinal data, to characterize bladder motion and deformation between fractions. This method is based on a principal component analysis (PCA) of bladder shapes to obtain the dominant eigen...
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#1K. Gnep (University of Rennes)H-Index: 8
#1Khemara Gnep (University of Rennes)H-Index: 6
Last. Renaud de Crevoisier (University of Rennes)H-Index: 28
view all 12 authors...
Purpose To explore the association between magnetic resonance imaging (MRI), including Haralick textural features, and biochemical recurrence following prostate cancer radiotherapy. Materials and Methods In all, 74 patients with peripheral zone localized prostate adenocarcinoma underwent pretreatment 3.0T MRI before external beam radiotherapy. Median follow-up of 47 months revealed 11 patients with biochemical recurrence. Prostate tumors were segmented on T2-weighted sequences (T2-w) and contour...
81 CitationsSource
#1J. ZhuH-Index: 6
#2Antoine SimonH-Index: 17
Last. Renaud de Crevoisier (French Institute of Health and Medical Research)H-Index: 28
view all 9 authors...
Background: To assess the benefits of bladder wall sub-volume equivalent uniform dose (EUD) constraints in prostate cancer intensity-modulated radiotherapy (IMRT) planning. Methods: Two IMRT plans, with and without EUD constraints on the bladder wall, were generated using beams that deliver 80 Gy to the prostate and 46 Gy to the seminal vesicles and were compared in 53 prostate cancer patients. The bladder wall was defined as the volume between the external manually delineated wall and a contrac...
5 CitationsSource
#1Julie LeseurH-Index: 6
#2Geoffrey Roman-Jimenez (University of Rennes)H-Index: 3
Last. Renaud de Crevoisier (French Institute of Health and Medical Research)H-Index: 28
view all 12 authors...
Abstract Purpose To describe the evolution and to assess the predictive value of metabolic parameters with different SUV threshold segmentations calculated from two 18F-FDG-PET/CT, one prior to and the other one during concomitant chemoradiation therapy (CCRT), for locally-advanced cervical cancer (LACC). Material and methods 53 patients treated for LACC by CCRT underwent FDG-PET/CT before treatment (PET1) and another one at 40Gy (PET2). The PET analyzed parameters were: maximum standardized upt...
19 CitationsSource
Aug 1, 2016 in EMBC (International Conference of the IEEE Engineering in Medicine and Biology Society)
#1Geoffrey Roman-Jimenez (French Institute of Health and Medical Research)H-Index: 1
#2Oscar Acosta (French Institute of Health and Medical Research)H-Index: 21
Last. Renaud de Crevoisier (French Institute of Health and Medical Research)H-Index: 28
view all 9 authors...
The ability to predict tumor recurrence after chemoradiotherapy of locally advanced cervical cancer is a crucial clinical issue to intensify the treatment of the most high-risk patients. The objective of this study was to investigate tumor metabolism characteristics extracted from pre- and per-treatment 18F-FDG PET images to predict 3-year overall recurrence (OR). A total of 53 locally advanced cervical cancer patients underwent pre- and per-treatment 18F-FDG PET (respectively PET1 and PET2). Tu...
2 CitationsSource
Aug 1, 2016 in EMBC (International Conference of the IEEE Engineering in Medicine and Biology Society)
#1Lina Guzman (French Institute of Health and Medical Research)H-Index: 2
#2Frederic Commandeur (French Institute of Health and Medical Research)H-Index: 13
Last. Renaud de Crevoisier (French Institute of Health and Medical Research)H-Index: 28
view all 9 authors...
Registration of histopathology volumes to Magnetic Resonance Images(MRI) is a crucial step for finding correlations in Prostate Cancer (PCa) and assessing tumor agressivity. This paper proposes a two-stage framework aimed at registering both modalities. Firstly, Speeded-Up Robust Features (SURF) algorithm and a context-based search is used to automatically determine slice correspondences between MRI and histology volumes. This step initializes a multimodal nonrigid registration strategy, which a...
3 CitationsSource
#1Pengcheng ZhangH-Index: 2
#2Antoine Simon (University of Rennes)H-Index: 17
Last. Renaud de CrevoisierH-Index: 28
view all 12 authors...
Purpose In oropharyngeal cancer adaptive radiation therapy (ART), this study aimed to quantify the dosimetric benefit of numerous replanning strategies, defined by various numbers and timings of replannings, with regard to parotid gland (PG) sparing. Material and methods Thirteen oropharyngeal cancer patients had one planning and then six weekly CT scans during the seven weeks of IMRT. Weekly doses were recalculated without replanning or with replanning to spare the PG. Sixty-three ART scenarios...
23 CitationsSource
#1G. Dréan (University of Rennes)H-Index: 8
#2Oscar Acosta (University of Rennes)H-Index: 21
Last. Renaud de Crevoisier (University of Rennes)H-Index: 28
view all 11 authors...
Abstract Background and purpose To identify rectal subregions at risks (SRR) highly predictive of 3-year rectal bleeding (RB) in prostate cancer IMRT. Materials and methods Overall, 173 prostate cancer patients treated with IMRT/IGRT were prospectively analyzed, divided into "training" ( n =118) and "validation" cohorts ( n =53). Dose–volume histograms (DVHs) were calculated in three types of rectal subregions: "geometric", intuitively defined (hemi-rectum,…); "personalized", obtained by non-rig...
32 CitationsSource
#1G. Dréan (University of Rennes)H-Index: 8
#2Oscar Acosta (University of Rennes)H-Index: 21
Last. Pascal Haigron (University of Rennes)H-Index: 21
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Purpose: Recent studies revealed a trend toward voxelwise population analysis in order to understand the local dose/toxicity relationships in prostate cancer radiotherapy. Such approaches require, however, an accurate interindividual mapping of the anatomies and 3D dose distributions toward a common coordinate system. This step is challenging due to the high interindividual variability. In this paper, the authors propose a method designed for interindividual nonrigid registration of the rectum a...
16 CitationsSource
#1E. MeyerH-Index: 2
#2Dinu StefanH-Index: 7
Last. Florence JolyH-Index: 58
view all 19 authors...
e16105Background: RCC is considered as radioresistant and radiation therapy of metastases is usually reserved only to palliate symptoms. However, by delivering ablative doses, SRT may increase loca...
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