Renaud de Crevoisier
University of Rennes
CancerInternal medicineRadiologyUrologySurgeryMagnetic resonance imagingOncologyArtificial intelligenceImage registrationPattern recognitionProstateProstate cancerRectumPopulationNuclear medicineComputer visionComputer scienceRadiation therapyMedicineImage-guided radiation therapy
138Publications
28H-index
2,670Citations
Publications 137
Newest
#1Oscar Acosta (University of Rennes)H-Index: 21
#2G. Dréan (University of Rennes)H-Index: 8
Last. Renaud de Crevoisier (University of Rennes)H-Index: 28
view all 7 authors...
The majority of current models utilized for predicting toxicity in prostate cancer radiotherapy are based on dose–volume histograms. One of their main drawbacks is the lack of spatial accuracy, since they consider the organs as a whole volume and thus ignore the heterogeneous intra-organ radio-sensitivity. In this paper, we propose a dose-image-based framework to reveal the relationships between local dose and toxicity. In this approach, the three-dimensional (3D) planned dose distributions acro...
51 CitationsSource
#1Mathieu Rubeaux (French Institute of Health and Medical Research)H-Index: 10
#2Antoine Simon (French Institute of Health and Medical Research)H-Index: 17
Last. Pascal Haigron (French Institute of Health and Medical Research)H-Index: 21
view all 7 authors...
Image-Guided Radiation Therapy (IGRT) aims at increasing the precision of radiation dose delivery. In the context of prostate cancer, a planning Computed Tomography (CT) image with manually defined prostate and organs at risk (OAR) delineations is usually associated with daily Cone Beam Computed Tomography (CBCT) follow-up images. The CBCT images allow to visualize the prostate position and to reposition the patient accordingly. They also should be used to evaluate the dose received by the organ...
7 CitationsSource
53 Background: Tools are needed to predict toxicity after prostate cancer treatment. The objective of the study was to analyze late urinary toxicity after prostate cancer radiotherapy (RT) by symptom description and identification of patient characteristics or treatment parameters allowing for the generation of nomograms. Methods: 965 patient received a median total dose of 70 Gy (range, 65-80 Gy) for localized prostate cancer, using different fractionations (2 or 2.5 Gy/day) and RT techniques. ...
Source
#1Lionel PerrierH-Index: 14
#2Magali MorelleH-Index: 14
Last. Renaud de Crevoisier (French Institute of Health and Medical Research)H-Index: 28
view all 16 authors...
Abstract Purpose This cost analysis aimed to quantify the cost of IGRT in relation to IGRT frequency and modality with Cone Beam Computed Tomography (CBCT) or orthogonal electronic portal imaging with fiducial markers (EPI-FM). Material and methods Patients undergoing IGRT for localized prostate cancer were randomized into two prostate control frequencies (daily or weekly). Costs were calculated based on the micro-costing results according to hospitals' perspectives (in Euros, 2009) and the time...
31 CitationsSource
#1Lionel PerrierH-Index: 14
#2Magali MorelleH-Index: 14
Last. Renaud de CrevoisierH-Index: 28
view all 20 authors...
Purpose of this study was to determine the effect of waiting time for radiotherapy on overall survival of patients with glioblastoma treated in the EORTC-NCIC trial at 18 centers in France. A total of 400 adult patients with glioblastoma who were treated between January 1, 2006 and December 31, 2006 were included. There were 282 patients with “minimum criteria” according to the EORTC-NCIC trial: (i) concurrent chemotherapy with temozolomide; and (ii) age between 18 and 70 years old. Among these ...
42 CitationsSource
May 2, 2012 in ISBI (International Symposium on Biomedical Imaging)
#1G. Dréan (French Institute of Health and Medical Research)H-Index: 8
#2Oscar Acosta (French Institute of Health and Medical Research)H-Index: 21
Last. Pascal Haigron (French Institute of Health and Medical Research)H-Index: 21
view all 5 authors...
Toxicity prediction is crucial in prostate cancer radiotherapy. There is thus a need to model voxel-wise relationships between dose distribution and toxicity events. However, building such a model is challenging due to difficulties in the mapping of the organs and of the dose distribution. We designed an organ-driven registration method merging the deformation fields computed for registrations first of the computed tomography scans and second of the organs delineations. The merging was done by w...
7 CitationsSource
May 2, 2012 in ISBI (International Symposium on Biomedical Imaging)
#1Juan David Ospina (French Institute of Health and Medical Research)H-Index: 8
#2Oscar Acosta (French Institute of Health and Medical Research)H-Index: 21
Last. Pascal Haigron (French Institute of Health and Medical Research)H-Index: 21
view all 5 authors...
In population analysis, the images of different groups can be compared to locate the effects of a particular disease or treatment and also to generate biomarkers that help in the diagnosis process. Voxel-Based Morphometry (VBM) is a set of widely extended techniques to compare groups of images. VBM involves image normalization, image smoothing, statistical map generation and correction for hypothesis testing. In this paper, we propose the use of a nonparametric mixed-effect model to study Alzhei...
1 CitationsSource
#1Fabio MartínezH-Index: 6
#2Oscar Acosta (French Institute of Health and Medical Research)H-Index: 21
Last. Eduardo RomeroH-Index: 21
view all 4 authors...
The challenge in prostate cancer radiotherapy is to deliver the planned dose to the prostate, sparing as much as possible the neighboring organs, namely bladder and rectum. If a lower amount of dose, compared to the prescription, is delivered to the prostate, the risk of failure may increase. Likewise, if higher doses are delivered to the neighboring organs, undesirable side effects may occur. Accurate localization of prostate and organs at risk is therefore a bottleneck in radiotherapy. In rece...
Source
#1Magali MorelleH-Index: 14
#2Lionel PerrierH-Index: 14
Last. P. DudouetH-Index: 7
view all 6 authors...
L'objectif principal de l'etude economique etait de mesurer de facon prospective et randomisee les surcouts d'une frequence quotidienne par comparaison a une frequence hebdomadaire des controles de positionnement du patient dans le cadre d'une radiotherapie guidee par l'image (image-guided radiotherapy [IGRT]) de cancers de la prostate, en prenant en compte les differentes modalites d'imagerie tridimensionnelle : tomographie conique (cone beam computed tomography [CBCT]) et implants de grains d'...