Hao Liu
Southern Medical University
CancerInternal medicineRadiologySurgeryOncologyRetrospective cohort studyRandomized controlled trialStage (cooking)ChemistryLaparoscopic surgeryMetastasisLaparoscopyGastrectomyLymph nodeCancer researchProportional hazards modelColorectal cancerMedicineCohortBiologyGastroenterology
Publications 153
#1Tian Lin (Southern Medical University)H-Index: 12
#2Tingyu Mou (Southern Medical University)H-Index: 14
Last. Guoxin Li (Southern Medical University)H-Index: 33
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Background Reduced port laparoscopic surgery (RPLS), as a more minimally invasive treatment alternative to conventional laparoscopic surgery (CLS), has been increasing in recent years. 1 With the accumulation of surgical experience and improvements in surgical techniques, the indication of RPLS has been gradually extended from benign diseases to malignant tumors, including gastric cancer. 2, 3, 4 However, due to the lack of counteraction and triangulation, lymphadenectomy during reduced port lap...
2 CitationsSource
#1Kari HemminkiH-Index: 123
#2Hao LiuH-Index: 22
Last. Jan SundquistH-Index: 91
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#1Guoxin Li (Southern Medical University)H-Index: 33
#2Jiang YuH-Index: 27
Last. Chen XinhuaH-Index: 4
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The laparoscopic surgery for gastrointestinal cancer developed slowly and was at a crossroad of choice at the beginning of the 21st century. However, the team of laparoscopic surgery in Nanfang Hospital was keenly conscious that minimally invasive surgery (MIS) would bring new era to the treatment of gastrointestinal cancer. Therefore, our team went into the exploration of laparoscopic surgery for gastrointestinal cancer: (1) researching a series of anatomical theories for MIS; (2) lucubrating t...
#1Tao Chen (Southern Medical University)H-Index: 9
#2Haibo Qiou (SYSU: Sun Yat-sen University)H-Index: 1
Last. Guoxin Li (Southern Medical University)H-Index: 33
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OBJECTIVE:To evaluate and compare the value of Modified NIH criteria and AFIP criteria for the risk classification of gastrointestinal stromal tumors (GIST). METHODS:Clinicopathological and follow-up data of 539 patients diagnosed as primary GIST with or without irregular tyrosine kinase inhibitors in the Nanfang Hospital(n=143), Sun Yat-sen University Cancer Center (n=138), Guangdong Provincial People's Hospital (n=102) and Wuhan Union Hospital (n=156) from January 2012 to December 2015 were re...
1 CitationsSource
#1Wenjun Liu (Southern Medical University)H-Index: 3
#2Shuang Wang (Southern Medical University)H-Index: 21
Last. Hao Liu (Southern Medical University)H-Index: 22
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In our previous studies, a functionally unknown gene, family with sequence similarity 172, member A (FAM172A), was identified. High levels of FAM172A suppressed the cell cycle process, arresting HepG2 cells in G1/S and inhibiting cell proliferation. The present study aimed to confirm the expression levels of FAM172A and nucleotide-binding protein 1 (NUBP1) in colorectal cancer (CRC) tissues and normal colorectal tissues. The impact of FAM172A and NUBP1 on the prognosis of patients with CRC was a...
3 CitationsSource
#1Jin Li (Southern Medical University)H-Index: 11
#2Li Zhen (Southern Medical University)H-Index: 8
Last. Guoxin Li (Southern Medical University)H-Index: 33
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: Circular RNAs are a large class of noncoding RNA that have shown huge capabilities as gene regulators. Recent evidence suggest that circular RNAs are associated with many diseases, especially cancer. However, little attention has been focused on the expression and function of circular RNA in gastric cancer (GC). In this study, we demonstrate that the expression of circ-104916 is downregulated in GC tissues and cell lines. A lower expression of circ-104916 appeared in deeper invasion depth, hig...
43 CitationsSource
#1Yan Zhang (Southern Medical University)H-Index: 7
#2Hao Liu (Southern Medical University)H-Index: 22
Last. Guoxin Li (Southern Medical University)H-Index: 33
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Abstract Although CircRNA_100269 is a biomarker used to predict cancer recurrence, its expression and function in gastric cancer (GC) remain unknown. In this study, the expression of circRNA_100269 and its potential downstream miRNA targets were investigated. The molecular function and regulatory mechanism of circRNA_100269 in GC cell lines were also elucidated. The expression levels of circRNA_100269 and its linear isomer LPHN2 mRNA were found to be downregulated (p<0.01) in GC tissues. The tar...
136 CitationsSource
#1Wenjun Liu (Southern Medical University)H-Index: 3
#2Kai Qian (Southern Medical University)H-Index: 4
Last. Hao Liu (Southern Medical University)H-Index: 5
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Abstract Accumulating evidence shows that mircroRNAs (miRNAs) play a crucial role in the development of colorectal cancer. In our previous study, FAM172A was demonstrated to be a novel tumor suppressor gene in CRC. Therefore, the aim of the present study was to identify whether the miR‑27a could be a diagnostic and prognostic marker and the regulatory relationships between miR‑27a and FAM172A. We demonstrated high levels of miR‑27a expression in tissues of patients with CRC as well as in CRC cel...
9 CitationsSource
#1Ruoyan LiuH-Index: 5
#2Ya-nan Wang (Southern Medical University)H-Index: 11
Last. Guoxin Li (Southern Medical University)H-Index: 33
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Background The advantages of reduced-port laparoscopic surgery (RPLS) for rectosigmoid cancer treatment have been disputed. This study evaluated the outcomes of RPLS compared to conventional laparoscopic surgery (CLS) for rectosigmoid cancer.
10 CitationsSource
#1Xiaolong Qi (Southern Medical University)H-Index: 23
#2Yuming Jiang (Southern Medical University)H-Index: 15
Last. Guoxin Li (Southern Medical University)H-Index: 33
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e15594Background: TNM staging system is not adequate to define the prognosis of patients with gastric cancer (GC). This system is also unable to predict whether the GC patients are likely to benefi...
1 CitationsSource