Hao Liu
Southern Medical University
CancerInternal medicineRadiologySurgeryOncologyRetrospective cohort studyRandomized controlled trialStage (cooking)ChemistryLaparoscopic surgeryMetastasisLaparoscopyGastrectomyLymph nodeCancer researchProportional hazards modelColorectal cancerMedicineCohortBiologyGastroenterology
Publications 153
#1Jia Wang (Xi'an Jiaotong University)H-Index: 7
#2Jie Zuo (Xi'an Jiaotong University)H-Index: 5
Last. Hao Liu (Xi'an Jiaotong University)H-Index: 1
view all 9 authors...
: Glioblastoma (GBM) is one of the most malignant tumors in adults, associated with severe outcomes (median survival, <2 years). Multiple mechanisms are known to be involved in tumor recurrence and treatment resistance in GBM, however, the key regulator for GBM tumorigenesis and therapy resistance remains unclear. To clarify a novel potential functional mechanism of GBM recurrence, a wide range of experiments including in vitro molecular biological experiments and in vivo intracranial xenograft ...
6 CitationsSource
#1Tao ChenH-Index: 9
#2Liangying YeH-Index: 1
Last. Guoxin LiH-Index: 33
view all 14 authors...
BACKGROUND: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumor type in the gastrointestinal system. Presently, various classification systems to prognosticate GISTs have been proposed. AIM: To evaluate the application value of four different risk stratification systems for GISTs. METHODS: Patients who were diagnosed with GISTs and underwent surgical resection at four hospitals from 1998 to 2015 were identified from a database. Risk of recurrence was stratified by the m...
1 CitationsSource
#1Ya-nan Wang (Southern Medical University)H-Index: 11
#2Haijun Deng (Southern Medical University)H-Index: 13
Last. Guoxin Li (Southern Medical University)H-Index: 33
view all 7 authors...
Objective The objective of the study is to evaluate the short-term outcomes of single-incision plus one-port surgery (SILS + 1) compared with conventional laparoscopic surgery (CLS) for colonic cancer.
8 CitationsSource
#1Huanan Wang (Southern Medical University)H-Index: 3
#2Guangxu Deng (Southern Medical University)H-Index: 2
Last. Guoxin Li (Southern Medical University)H-Index: 33
view all 9 authors...
Hsp90ab1 is upregulated in numerous solid tumors, which is thought to induce the angiogenesis and promote cancer metastasis. However, it’s actions in gastric cancer (GC) has not been exhibited. In this study, Hsp90ab1 was demonstrated to be overexpressed and correlated with the poor prognosis, proliferation and invasion of GC. Ectopic expression of Hsp90ab1 promoted the proliferation and metastasis of GC cells both in vitro in cell line models of GC and in vivo using two different xenograft mous...
27 CitationsSource
#1Weihong Guo (Southern Medical University)H-Index: 6
#2Lizhi Deng (SYSU: Sun Yat-sen University)H-Index: 3
Last. Yanfeng Hu (Southern Medical University)H-Index: 22
view all 13 authors...
AIM: Our previous research has introduced sericin micelles to reverse drug resistance. However, these micelles could not selectively bind to gastric cancer (GC) cells. We developed vitamin B12 (VB12) conjugated sericin micelles for targeted GC therapy. MATERIALS & METHODS: We used VB12, sericin, synthetic poly(γ-benzyl-L-glutamate) (PBLG) and paclitaxel (PTX) to develop VB12-conjugated and PTX-loaded micelles (VB12-sericin-PBLG-PTX). Then we explored their physicochemical properties, cellular up...
9 CitationsSource
#1Hao Liu (Southern Medical University)H-Index: 22
#2Hao Wang (Southern Medical University)H-Index: 4
Last. Meijuan Zhou (Southern Medical University)H-Index: 1
view all 7 authors...
Abstract Background and purpose Neoadjuvant chemoradiation (nCRT) could reduce tumor infiltrating lymphocytes. We examined absolute lymphocyte count (ALC) nadir during nCRT, pathologic response and prognosis for locally advanced rectal cancer (LARC). Materials and methods 102 patients with LARC (cT3–4N0, or node-positive) treated between 2010 and 2015 with nCRT followed by complete resection were analyzed. The ALC value was obtained prior to, weekly during the treatment, and one month after nCRT...
7 CitationsSource
#1Tian Lin (Southern Medical University)H-Index: 12
#2Jiang Yu (Southern Medical University)H-Index: 27
Last. Guoxin Li (Southern Medical University)H-Index: 33
view all 9 authors...
OBJECTIVE: To evaluate the short-term efficacy and cosmetic effect of dual-port laparoscopic distal gastrectomy (DPLDG) for gastric cancer. METHODS: Thirty consecutive patients underwent DPLDG at the Department of General Surgery, Nanfang Hospital from November 2016 to August 2018. INCLUSION CRITERIA: (1) age of 18 to 75 years; (2) primary gastric adenocarcinoma confirmed pathologically by endoscopic biopsy; (3) tumor located at middle-low stomach and planned for distal gastrectomy; (4) cT1b-2N0...
#1Bao-yu Zhao (Southern Medical University)
#2Zhenzhan Zhang (Southern Medical University)H-Index: 1
Last. Guoxin Li (Southern Medical University)H-Index: 33
view all 8 authors...
Background. The optimal extent of gastrectomy and lymphadenectomy for esophagogastric junction (EGJ) cancer is controversial. Our study aimed to compare the long-term survival of transhiatal proximal gastrectomy with extended periproximal lymphadenectomy (THPG with EPL) and transhiatal total gastrectomy with complete perigastric lymphadenectomy (THTG with CPL) for patients with the stomach-predominant form of EGJ cancer. Methods. Between January 2004, and August 2015, 306 patients with Siewert I...
#1Tao Chen (Southern Medical University)H-Index: 9
#2Shangqing Liu (Southern Medical University)H-Index: 1
Last. Guoxin Li (Southern Medical University)H-Index: 33
view all 17 authors...
Abstract This study aimed to develop and validate a prognostic nomogram for recurrence-free survival (RFS) after surgery in the absence of adjuvant therapy to guide the selection for adjuvant imatinib therapy based on Residual Neural Network (ResNet). The ResNet model was developed based on contrast-enhanced computed tomography (CE-CT) in a training cohort consisted of 80 patients pathologically diagnosed gastrointestinal sromal tumors (GISTs) and validated in internal and external validation co...
11 CitationsSource
#1Hao Wang (Southern Medical University)H-Index: 4
#2Tingyu Mou (Southern Medical University)H-Index: 14
Last. Guoxin Li (Southern Medical University)H-Index: 33
view all 9 authors...
Background Laparoscopy-assisted distal gastrectomy (LADG) for gastric cancer has been widely applied; however, its oncologic efficacy has yet been well established. The study aimed to compare the long-term oncologic outcomes of LADG versus open distal gastrectomy (ODG) on gastric cancer.
4 CitationsSource