Christian Heiss
University of Georgia
VasodilationInternal medicineEndocrinologyBiomedical engineeringSurgeryCardiologyBone remodelingChemistryMaterials scienceIn vivoOsteoporosisEndotheliumBrachial arteryEndothelial dysfunctionNitric oxideBiochemistryMedicineBone healingBlood pressureBiologyPharmacology
Publications 481
#1Lucas BuschH-Index: 3
#2Manuel SternH-Index: 4
Last. Roberto SansoneH-Index: 14
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Abstract null null Objectives null Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is standard of care in patients with peripheral artery disease (PAD) after percutaneous transluminal angioplasty (PTA). However, high on treatment platelet reactivity (HTPR) to DAPT is frequent and associated with major adverse limb events (MALE) in PAD patients. Nevertheless, association of MALE and HTPR in patients with critical limb ischemia (CLI) is not known. Moreover, comorbidities might confou...
#1Thaqif El KhassawnaH-Index: 14
#2Gero KnappH-Index: 1
Last. Markus RuppH-Index: 7
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Periprosthetic femoral fracture (PFF) is a devastating complication. Here, the authors aimed to determine the influence of the timing of surgery as a risk factor for mortality and poor postoperative outcome in patients suffering from PFF. A retrospective descriptive analysis of patients treated for PFF between January 2010 and March 2018 was performed. In addition to patient and treatment characteristics, we assessed mortality rates and postoperative functional outcome by using the Harris Hip an...
#1Alexandre Presas (UPC: Polytechnic University of Catalonia)H-Index: 16
#2David Valentin (UPC: Polytechnic University of Catalonia)H-Index: 14
Last. Christian Heiss (University of Giessen)H-Index: 62
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Abstract null null Motive. null External vibration excitation might be key to many novel non-surgical interventions for pathologies in the musculoskeletal system and in other parts of the human organism. Lack of understanding about vibration patterns, their controllability, and reproducibility are three limitations of ongoing research. This study establishes a bovine vibration model and animal model replacements for future research. null null null Methods null We used biological samples ( null n...
Optical coherence tomography angiography (OCTA) performs non-invasive visualization and characterization of microvasculature in research and clinical applications mainly in ophthalmology and dermatology. A wide variety of instruments, imaging protocols, processing methods and metrics have been used to describe the microvasculature, such that comparing different study outcomes is currently not feasible. With the goal of contributing to standardization of OCTA data analysis, we report a user-frien...
#1Lucia Mazzolai (UNIL: University of Lausanne)H-Index: 33
#2Adriano Alatri (UNIL: University of Lausanne)H-Index: 13
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Although COVID-19 seems to be the leading topic in researcha number of outstanding studies have been published in the field of aorta and peripheral vascular diseases likely affecting our clinical practice in the near future. This review article highlights key research on vascular diseases published in 2020. Some studies have shed light in the pathophysiology of aortic aneurysm and dissection suggesting a potential role for kinase inhibitors as new therapeutic options. A first proteogenomic study...
1 CitationsSource
#1Fabian Hemm (University of Giessen)
#2Monika Fijak (University of Giessen)H-Index: 17
Last. Katrin S. Lips (University of Giessen)H-Index: 32
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Investigations in male patients with fertility disorders revealed a greater risk of osteoporosis. The rodent model of experimental autoimmune-orchitis (EAO) was established to analyze the underlying mechanisms of male infertility and causes of reduced testosterone concentration. Hence, we investigated the impact of testicular dysfunction in EAO on bone status. Male mice were immunized with testicular homogenate in adjuvant to induce EAO (n = 5). Age-matched mice were treated with adjuvant alone ...
#1Lucas BuschH-Index: 3
#2Yvonne HeinenH-Index: 7
Last. Malte KelmH-Index: 90
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Background Arterial hypertension affects cardiovascular outcome in patients with peripheral artery disease (PAD). We hypothesized that angioplasty of peripheral arterial stenoses decreases aortic (aBP) and brachial blood pressure (bBP). Methods and Results In an index cohort (n=30), we simultaneously measured aBP, bBP, augmentation index (AIx), and aortic pulse wave velocity (PWV) before and after angioplasty of the iliac and femoropopliteal arteries; diagnostic angiography served as a control. ...
#1Asif Shajahan (UGA: University of Georgia)H-Index: 10
#2Lauren E. Pepi (UGA: University of Georgia)H-Index: 4
Last. Parastoo Azadi (UGA: University of Georgia)H-Index: 47
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The COVID-19 pandemic is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Similar to other coronaviruses, its particles are composed of four structural proteins: spike (S), envelope (E), membrane (M), and nucleocapsid (N) proteins. S, E, and M proteins are glycosylated, and the N protein is phosphorylated. The S protein is involved in the interaction with the host receptor human angiotensin-converting enzyme 2 (hACE2), which is also heavily glycosylated. Recent studies...
1 CitationsSource
#1Christoph KalkaH-Index: 24
Last. Christian Heiss (University of Surrey)H-Index: 62
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