Courtney Lang
Harvard University
InsulaDefault mode networkMagnetic resonance imagingPsychologyMultivariate statisticsNeuroscienceVoxel-based morphometryOsteoarthritisVentral striatumGrey matterAnterior cingulate cortexAutism spectrum disorderPutamenMajor depressive disorderStriatumNeuropathologyChronic painPrefrontal cortexSupplementary motor areaFunctional connectivityChronic low back painAudiologyAcupunctureNeuroimagingResting state fMRIText miningMedicineCohortPhysical medicine and rehabilitation
28Publications
15H-index
454Citations
Publications 28
Newest
#1Jin CaoH-Index: 7
#2Yiheng TuH-Index: 16
Last. Jian KongH-Index: 67
view all 10 authors...
Animal studies suggest that caffeine may interfere with acupuncture analgesia. This study investigated the modulation effect of daily caffeine intake on acupuncture analgesia in 27 healthy subjects using a crossover design. We found that real acupuncture increased pain thresholds compared to sham ac
1 CitationsSource
#1Yiheng TuH-Index: 16
#2Fang ZengH-Index: 21
Last. Jian KongH-Index: 67
view all 16 authors...
Objective To identify and validate an fMRI-based neural marker for migraine without aura (MwoA) and to examine its association with treatment response. Methods We conducted cross-sectional studies with resting-state fMRI data from 230 participants and machine learning analyses. In studies 1 through 3, we identified, cross-validated, independently validated, and cross-sectionally validated an fMRI-based neural marker for MwoA. In study 4, we assessed the relationship between the neural marker and...
16 CitationsSource
#1Jiao Liu (FJUTCM: Fujian University of Traditional Chinese Medicine)H-Index: 12
#2Lidian Chen (FJUTCM: Fujian University of Traditional Chinese Medicine)H-Index: 30
Last. Jian Kong (Harvard University)H-Index: 67
view all 18 authors...
Abstract Objectives Knee osteoarthritis (KOA) is a common degenerative joint disease with no satisfactory intervention. Recently, both physical and mindfulness exercises have received considerable attention for their implications in KOA pain management, and the dorsolateral prefrontal cortex (DLPFC) has displayed a critical role in pain modulation. This study aimed to comparatively investigate the modulation effects of different exercises using multidisciplinary measurements. Methods 140 KOA pat...
10 CitationsSource
#1Jiao Liu (FJUTCM: Fujian University of Traditional Chinese Medicine)H-Index: 12
#2Lidian Chen (FJUTCM: Fujian University of Traditional Chinese Medicine)H-Index: 30
Last. Jian Kong (Harvard University)H-Index: 67
view all 18 authors...
Abstract Background Knee osteoarthritis is a prevalent disorder with unsatisfactory treatment options. Both physical and mindful exercises may be able to relieve its pain symptoms. We compared the modulatory effects of different exercise modalities on the periaqueductal grey (PAG) and ventral tegmental area (VTA), which play important roles in descending opioidergic pathways and reward/motivation systems in patients with knee osteoarthritis. Methods We recruited and randomised 140 patients into ...
14 CitationsSource
#1Binlong Zhang (Harvard University)H-Index: 4
#2Minyoung Jung (Harvard University)H-Index: 12
Last. Jian Kong (Harvard University)H-Index: 67
view all 18 authors...
Abstract Background Previous studies have found widespread pain processing alterations in the brain in chronic low back pain (cLBP) patients. We aimed to (1) identify brain regions showing altered amplitude of low-frequency fluctuations (ALFF) using MRI and use these regions to discriminate cLBP patients from healthy controls (HCs) and (2) identify brain regions that are sensitive to cLBP pain intensity changes. Methods We compared ALFF differences by MRI between cLBP subjects (90) and HCs (74),...
20 CitationsSource
#1Jin Cao (Beijing University of Chinese Medicine)H-Index: 7
#2Yiheng Tu (Harvard University)H-Index: 16
Last. Jian Kong (Harvard University)H-Index: 67
view all 9 authors...
: Acupuncture can provide therapeutic analgesic benefits but is limited by its cost and scheduling difficulties. Guided imagery is a commonly used method for treating many disorders, such as chronic pain. The present study examined a novel intervention for pain relief that integrates acupuncture with imagery called video-guided acupuncture imagery treatment (VGAIT). A total of 27 healthy subjects were recruited for a crossover-design study that included 5 sessions administered in a randomized or...
14 CitationsSource
#1Fang Zeng (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 21
#2Ruirui Sun (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 7
Last. Jian KongH-Index: 67
view all 19 authors...
INTRODUCTION: The influence of sex on the prevalence and clinical manifestations of functional dyspepsia (FD) has recently been a topic of increasing interest. However, brain MRI pathology based on sexual dimorphism in FD has not yet been investigated. The amygdala, which plays a vital role in processing gastrointestinal signals, may be associated with the sex-related pathophysiology of FD. METHODS: We investigated the resting-state functional connectivity (rsFC) of amygdala subregions in patien...
8 CitationsSource
#1Minyoung Jung (University of Fukui)H-Index: 12
#2Yiheng Tu (Harvard University)H-Index: 16
Last. Jian Kong (Harvard University)H-Index: 67
view all 7 authors...
Background Both attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are neurodevelopmental disorders with a high prevalence. They are often comorbid and both exhibit abnormalities in sustained attention, yet common and distinct neural patterns of ASD and ADHD remain unidentified. Aims To investigate shared and distinct functional connectivity patterns in a relatively large sample of boys (7- to 15-year-olds) with ADHD, ASD and typical development matched by age, ge...
14 CitationsSource
#1Yiheng Tu (Harvard University)H-Index: 16
#2Minyoung Jung (Harvard University)H-Index: 12
Last. Jian KongH-Index: 67
view all 15 authors...
AbstractAccumulating evidence has shown that complicated brain systems are involved in the development and maintenance of chronic low back pain (cLBP), but the association between brain functional changes and clinical outcomes remains unclear. Here, we used resting-state functional magnetic resonanc
24 CitationsSource
#1Jiao Liu (FJUTCM: Fujian University of Traditional Chinese Medicine)H-Index: 12
#2Jing Tao (Harvard University)H-Index: 7
Last. Jian Kong (Harvard University)H-Index: 67
view all 14 authors...
: The default mode network (DMN) plays an important role in age-related cognitive decline. This study aims to explore the modulation effect of two mind-body interventions (Tai Chi Chuan and Baduanjin) on DMN in elderly individuals. Participants between 50 and 70 years old were recruited and randomized into a Tai Chi Chuan, Baduanjin or control group. The Wechsler Memory Scale-Chinese Revision and resting-state fMRI scans were administered at baseline and following 12 weeks of exercise. Seed-base...
15 CitationsSource