Fengwu Tang
SurgeryChemistryMesenchymal stem cellUmbilical cordGlial scarScarsSpinal cord injurySpinal stenosisSpinal cordStem cellStat3 Signaling PathwayNeurophysiological MonitoringTransplantationLumbarReactive oxygen speciesCell growthMedicinePI3K/AKT/mTOR pathwayScaffoldCell biology
7Publications
3H-index
125Citations
Publications 7
Newest
Source
#1Jipeng JiangH-Index: 1
#2Shanshan ZhangH-Index: 1
Last. Fengwu TangH-Index: 3
view all 7 authors...
Abstract To study the utility of neurophysiological monitoring in the micro-surgical treatments on children with Tethered Cord Syndrome (TCS). A total of 100 patients were included in this study. 51 children underwent micro-surgical treatments without neurophysiological monitoring (no monitoring group) from 2004 to 2009, whereas 49 children with neurophysiological monitoring (monitoring group) from 2010 to 2016. Postoperative evaluations demonstrated that more children in monitoring group (39, 8...
2 CitationsSource
#1Zhifeng Xiao (CAS: Chinese Academy of Sciences)H-Index: 49
#2Fengwu TangH-Index: 3
Last. Jianwu Dai (CAS: Chinese Academy of Sciences)H-Index: 69
view all 14 authors...
Stem cells and biomaterials transplantation hold a promising treatment for functional recovery in spinal cord injury (SCI) animal models. However, the functional recovery of complete SCI patients was still a huge challenge in clinic. Additionally, there is no clinical standard procedure available to diagnose precisely an acute patient as complete SCI. Here, two acute SCI patients, with injury at thoracic 11 (T11) and cervical 4 (C4) level respectively, were judged as complete injury by a stricte...
29 CitationsSource
#1Yannan Zhao (CAS: Chinese Academy of Sciences)H-Index: 41
#2Fengwu TangH-Index: 3
Last. Jianwu Dai (CAS: Chinese Academy of Sciences)H-Index: 69
view all 14 authors...
Regeneration of damaged neurons and recovery of sensation and motor function after complete spinal cord injury (SCI) are challenging. We previously developed a collagen scaffold, NeuroRegen, to promote axonal growth along collagen fibers and inhibit glial scar formation after SCI. When functionalized with multiple biomolecules, this scaffold promoted neurological regeneration and functional recovery in animals with SCI. In this study, eight patients with chronic complete SCI were enrolled to exa...
48 CitationsSource
#1Zhifeng Xiao (CAS: Chinese Academy of Sciences)H-Index: 49
#2Fengwu TangH-Index: 3
Last. Jianwu Dai (CAS: Chinese Academy of Sciences)H-Index: 69
view all 18 authors...
The objective of this clinical study was to assess the safety and feasibility of the collagen scaffold, NeuroRegen scaffold, one year after scar tissue resection and implantation. Scar tissue is a physical and chemical barrier that prevents neural regeneration. However, identification of scar tissue is still a major challenge. In this study, the nerve electrophysiology method was used to distinguish scar tissue from normal neural tissue, and then different lengths of scars ranging from 0.5–4.5 c...
43 CitationsSource
Objective To analyze the causes of surgical complications after treatment of lumbar disc herniation (LDH) and lumbar intervertebral foraminal stenosis by percutaneous transforaminal endoscopic discectomy (PTED). Methods From December 2009 to December 2014, 286 patients with LDH (N = 201) and lumbar intervertebral foraminal stenosis (N = 85) were confirmed by X-ray, CT or MRI and treated by PTED in our hospital. Visual Analogue Scale (VAS) was used to evaluate the degree of pain in each paitent b...
Source