Jennifer M. Miller
Cardiac function curveInternal medicineSurgeryCardiologyCoronary circulationBleedUmbilical cordCardiac catheterizationHeart failureVentricleStem-cell therapyHypoplastic left heart syndromeContext (language use)Heart diseaseCell basedPhases of clinical researchMedicineEjection fraction
2Publications
2H-index
22Citations
Publications 2
Newest
Abstract Objectives Staged surgical palliation for hypoplastic left heart syndrome results in an increased workload on the right ventricle serving as the systemic ventricle. Concerns for cardiac dysfunction and long-term heart failure have generated interest in first-in-infant, cell-based therapies as an additional surgical treatment modality. Methods A phase 1 clinical trial was conducted to evaluate the safety and feasibility of direct intramyocardial injection of autologous umbilical cord blo...
Source
#1Muhammad Yasir Qureshi (Mayo Clinic)H-Index: 12
#2Allison K. Cabalka (Mayo Clinic)H-Index: 31
Last. Karen MillerH-Index: 2
view all 19 authors...
Abstract Myocardial dysfunction after Fontan palliation for univentricular congenital heart disease is a challenging clinical problem. The medical treatment has a limited impact, with cardiac transplant being the ultimate management step. Cell-based therapies are evolving as a new treatment for heart failure. Phase 1 clinical trials using regenerative therapeutic strategies in congenital heart disease are ongoing. We report the first case of autologous bone marrow–derived mononuclear cell admini...
Source
This website uses cookies.
We use cookies to improve your online experience. By continuing to use our website we assume you agree to the placement of these cookies.
To learn more, you can find in our Privacy Policy.