Shuai Leng
Mayo Clinic
Imaging phantomOpticsPhysicsRadiologyIterative reconstructionArtificial intelligenceTomographyImage resolutionScannerRadiation doseNuclear medicineMedical imagingComputer visionMathematicsImage noiseComputer scienceComputed tomographyImage qualityMedicineDetector
308Publications
53H-index
8,144Citations
Publications 309
Newest
#1Hao Gong (Mayo Clinic)H-Index: 8
#2Lifeng YuH-Index: 48
Last. Cynthia H. McColloughH-Index: 76
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OBJECTIVE To investigate reader performance as a function of patient size for the detection of hepatic metastases when an automatic exposure control (AEC) system is used, which varies image noise as a function of patient size. METHODS Abdominal computed tomograhy examinations across 100, 120, 160, and 200 quality reference tube current-time product were collected, involving a cohort of 83 patients. Three radiologists identified hepatic metastases across all dose levels. Partial Spearman rank cor...
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#1Yong Hong Ding (Mayo Clinic)H-Index: 21
#2Mehdi Abbasi (Mayo Clinic)H-Index: 3
Last. Waleed Brinjikji (Mayo Clinic)H-Index: 58
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Background CT is the most commonly used imaging modality for acute ischemic stroke evaluation. There is growing interest to use pre-operative imaging to characterize clot composition in stroke. We performed an in-vitro study examining the ability of various CT techniques in differentiation between different clot types. Methods Five clot types with varying fibrin and red blood cells (RBCs) densities (5% RBC and 95% fibrin; 25% RBC and 75% fibrin; 50% RBC and 50% fibrin; 75% RBC and 25% fibrin; 95...
2 CitationsSource
#1Hao Gong (Mayo Clinic)H-Index: 8
#2Shengzhen Tao (Mayo Clinic)H-Index: 13
Last. Shuai Leng (Mayo Clinic)H-Index: 53
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Mega-voltage fan-beam Computed Tomography (MV-FBCT) holds potential in accurate determination of relative electron density (RED) and proton stopping power ratio (SPR) but is not widely available. To demonstrate the feasibility of MV-FBCT using a medical linear accelerator (LINAC) with a 2.5 MV imaging beam, an electronic portal imaging device (EPID) and multileaf collimators (MLCs). MLCs were used to collimate MV beam along z direction to enable a 1 cm width fan-beam. Projection data were acquir...
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#1Kishore Rajendran (Mayo Clinic)H-Index: 11
#2Martin Petersilka (Siemens)H-Index: 9
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
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We report a comprehensive evaluation of a full field-of-view (FOV) photon-counting detector (PCD) CT system using phantoms, and qualitatively assess image quality in patient examples. A whole-body PCD-CT system with 50 cm FOV, 5.76 cm z-detector coverage and two acquisition modes (standard: 144 × 0.4 mm collimation and ultra-high resolution, UHR: 120 × 0.2 mm collimation) was used in this study. Phantom scans were acquired to assess image uniformity, CT number accuracy, noise power spectrum, spa...
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#1Daniel Gomez-Cardona (Gundersen Health System)H-Index: 2
#1Daniel Gomez-Cardona (Gundersen Health System)H-Index: 5
Last. Kenneth A. Fetterly (Mayo Clinic)H-Index: 18
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PURPOSE Channelized Hotelling observer (CHO) models have been implemented to assess imaging performance in x-ray angiography systems. While current methods are appropriate for assessing unprocessed images of moving test objects upon uniform-exposure backgrounds, they are inadequate for assessing conditions which more appropriately mimic clinical imaging conditions including the combination of moving test objects, complex anthropomorphic backgrounds, and image processing. In support of this broad...
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#1Scott S. Hsieh (Mayo Clinic)H-Index: 1
#1Scott S. HsiehH-Index: 1
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
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The use of a photon counting detector in CT (PCD CT) is currently the subject of intense investigation and development. In this review article, we will describe potential clinical applications of this technology with a particular focus on the experience of our own institution with a prototype PCD CT scanner. PCDs have three primary advantages over conventional, energy integrating detectors (EIDs): they provide spectral information without need for a dedicated dual energy protocol; they are immun...
5 CitationsSource
2 CitationsSource
#1Nathan R. Huber (Mayo Clinic)H-Index: 2
#2Tara L. Anderson (Mayo Clinic)H-Index: 3
Last. Katrina N. Glazebrook (Mayo Clinic)H-Index: 21
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OBJECTIVE This study evaluated the clinical utility of a phantom-based convolutional neural network noise reduction framework for whole-body-low-dose CT skeletal surveys. MATERIALS AND METHODS The CT exams of ten patients with multiple myeloma were retrospectively analyzed. Exams were acquired with routine whole-body-low-dose CT protocol and projection noise insertion was used to simulate 25% dose exams. Images were reconstructed with either iterative reconstruction or filtered back projection w...
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1 CitationsSource
#1Hao Gong (Mayo Clinic)H-Index: 8
#2Jeffrey F. Marsh (Mayo Clinic)H-Index: 1
Last. Shuai Leng (Mayo Clinic)H-Index: 53
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Purpose: We developed a deep learning method to reduce noise and beam-hardening artifact in virtual monoenergetic image (VMI) at low x-ray energy levels. Approach: An encoder–decoder type convolutional neural network was implemented with customized inception modules and in-house-designed training loss (denoted as Incept-net), to directly estimate VMI from multi-energy CT images. Images of an abdomen-sized water phantom with varying insert materials were acquired from a research photon-counting-d...
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