S. Thambiraj
University of Madras
Colloidal goldConjugated systemPharmacokineticsSurface modificationAbsorption spectroscopyCancerInternal medicineTargeted drug deliveryNanomaterialsNuclear chemistryOncologyTransmission electron microscopyAdsorptionNanomedicineInfrared spectroscopyNanoparticleFourier transform infrared spectroscopyQuantum yieldNanotechnologyX-ray photoelectron spectroscopyChemistryMaterials scienceAdverse effectScanning electron microscopeMethyl violetBiocompatibilityEthylene glycolBiopolymerBrilliant greenDiseaseCelluloseDrug deliveryDrugProstate cancerTrisodium citrateVinyl alcoholDocetaxelChemical treatmentProstate glandLow toxicityEffective treatmentLower mortalitySpectroscopyRaman spectroscopyChemical engineeringCrystallinityCancer researchRadiation therapyColorectal cancerPEG ratioMedicineOrange (colour)FluorescencePortable water purification
8Publications
6H-index
207Citations
Publications 8
Newest
#1S. Thambiraj (University of Madras)H-Index: 6
#2R. VijayalakshmiH-Index: 1
Last. D. Ravi Shankaran (University of Madras)H-Index: 9
view all 3 authors...
Nanoformulation based drug delivery is one of the most important research areas in the field of nanomedicine, which provides promising alternatives to the limitations of conventional chemotherapy. Nano drug delivery enables improved pharmacokinetic profile, bioavailability and therapeutic efficiency compared to the regular chemotherapeutic drugs. Herein, we have established a simple method for the synthesis of docetaxel (Dtx) encapsulated poly (ethylene glycol) (PEG) functionalized gold nanopart...
1 CitationsSource
#1S. Thambiraj (University of Madras)H-Index: 6
#2S. ShruthiH-Index: 1
Last. D. Ravi Shankaran (University of Madras)H-Index: 9
view all 4 authors...
Abstract The effective use of the gold nanoparticle (AuNPs) conjugated drugs for targeted drug delivery applications is one of the most promising research areas in the field of cancer. Herein, we aimed to establish a nano drug conjugated with docetaxel as a possible therapy option. Gold nanoparticles were synthesized by chemical reduction method. This is followed by the conjugation with an anticancer drug, docetaxel (Dtx) by a non-covalent method and folic acid (FA) was conjugated by a covalent ...
9 CitationsSource
#1Soundararajan Hema (University of Madras)H-Index: 3
#2S. Thambiraj (University of Madras)H-Index: 6
Last. Dhesingh Ravi Shankaran (University of Madras)H-Index: 18
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Cancer is the second leading causes of death worldwide and it is one of the fatal diseases that kill millions of people every year. It is characterized by uncontrolled proliferation of cells and loss of apoptosis that generates an abnormal mass of cells or tumors. Prostate cancer (PCa) is one of the most common cancers in men and the risk is higher over the age of 55-65. Currently, PCa is the second most common cancer, which causes death in men has a high prevalence with relatively lower cancer ...
16 CitationsSource
#1S. Thambiraj (University of Madras)H-Index: 6
#2G. Sharmila (Bharathiar University)H-Index: 1
Last. D. Ravi Shankaran (University of Madras)H-Index: 9
view all 3 authors...
Abstract We developed a green adsorbent material from orange fruit peel for the removal of dyes from polluted water. The conversion of orange peels into green adsorbent was done by direct sunlight without using any chemical treatment. The adsorption study was carried with three different dyes namely, brilliant green, methyl violet, and solochrome black. Different concentrations of the dye solutions were prepared and evaluated for adsorption characteristics. The properties of the orange fruit pee...
5 CitationsSource
#1S. Thambiraj (University of Madras)H-Index: 6
#2Soundararajan Hema (University of Madras)H-Index: 3
Last. D. Ravi Shankaran (University of Madras)H-Index: 9
view all 3 authors...
Abstract Gold nanoparticles (AuNPs) have been receiving great attention over the years due to their unique optical, electrical and biological properties. The functionalization of AuNPs is an important research interest owing to its potential application in various areas including biomedical, defense, food and environmental. Herein, we demonstrate a simple and effective method for the synthesis of functionalized AuNPs. Gold nanoparticles were synthesized by chemical reduction method using trisodi...
7 CitationsSource
#1S. Thambiraj (University of Madras)H-Index: 6
#2Soundararajan Hema (University of Madras)H-Index: 3
Last. Dhesingh Ravi Shankaran (University of Madras)H-Index: 18
view all 3 authors...
BACKGROUND: Carcinoma of the prostate gland (PCa) is one of the most commonly diagnosed cancer diseases among men around the world. PCa has become the major considerable health and epidemic problem which causes death in men with a high prevalence and relatively lower mortality risk. The inability of conventional diagnosis tools to detect cancer at an early and potentially curable stage further hinders effective treatment options and spur demand for improved technologies. Nanoparticles are emergi...
6 CitationsSource
#1S. Thambiraj (University of Madras)H-Index: 6
#2D. Ravi Shankaran (University of Madras)H-Index: 9
Abstract We aimed to develop a simple and low-cost method for the production of high-performance cellulose nanomaterials from renewable and sustainable resources. Here, cellulose microcrystals (CMCs) were prepared by controlled acidic and basic hydrolysis of cotton from textile industry wastes. The resulted CMCs were further converted into cellulose nanocrystals (CNCs) with high crystallinity by acidic hydrolysis. The physicochemical characteristics and morphological feature of CMCs and CNCs wer...
64 CitationsSource
#1S. ThambirajH-Index: 6
#2D. Ravi Shankaran (University of Madras)H-Index: 9
Abstract Carbon quantum dots (CQDs) have great potential due to its advantageous characteristics of highly fluorescent nature and good stability. In this study, we aimed to develop a simple and efficient method for the green synthesis of fluorescent CQDs from sugarcane bagasse, a renewable and sustainable resource. The process involves the top down approach of chemical oxidation followed by exfoliation of sugarcane carbon. The synthesized CQDs was characterized by UV–vis absorption spectroscopy,...
87 CitationsSource