Francesca Di Lillo
Istituto Nazionale di Fisica Nucleare
Imaging phantomIrradiationOpticsPhysicsBiomedical engineeringTransverse planeSynchrotron radiationTomographyBeam (structure)KermaMaterials scienceMonte Carlo methodImage resolutionBreast imagingAustralian SynchrotronScannerRadiosurgeryMammographyDigital Breast TomosynthesisPartial Breast IrradiationNuclear medicineMonte carlo evaluationDose distributionBreast ctCollimated lightMonochromatic colorComputer scienceRadiation therapyBreast cancerComputed tomographyImage qualityHomogeneousDosimetryBremsstrahlungDetector
Publications 20
#1Renata Longo (UniTS: University of Trieste)H-Index: 26
#2Fulvia Arfelli (UniTS: University of Trieste)H-Index: 33
Last. Giuliana TrombaH-Index: 28
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Breast computed tomography (BCT) is an emerging application of X-ray tomography in radiological practice. A few clinical prototypes are under evaluation in hospitals and new systems are under development aiming at improving spatial and contrast resolution and reducing delivered dose. At the same time, synchrotron-radiation phase-contrast mammography has been demonstrated to offer substantial advantages when compared with conventional mammography. At Elettra, the Italian synchrotron radiation fac...
24 CitationsSource
#1Danail Ivanov (Technical University of Varna)H-Index: 2
#2Kristina Bliznakova (Technical University of Varna)H-Index: 6
Last. Zhivko Bliznakov (Technical University of Varna)H-Index: 8
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Breast physical phantoms are a basic tool for the assessment and verification of performance standards in daily clinical practice of x-ray breast imaging modalities. They are also invaluable in testing and evaluation of new x-ray breast modalities to be potentially established, e.g. breast computed tomography, dual-energy breast CT and phase-contrast mammography and tomography. Nowadays, there is a lack or there are only a limited number of breast physical phantoms available for this purpose. Th...
20 CitationsSource
#1Giovanni Mettivier (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 22
#2Illya Drebot (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 10
Last. Paolo Russo (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 24
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Purpose The development of compact sources of high brilliance, mono-chromatic, tunable X-rays with energy in the range 30–150 keV is a topical research field; applications in radiodiagnostics are foreseen. The aim of this work is to propose the use of a compact source based on X-ray Compton back-scattering (also known as Inverse Compton Source, ICS) developed within the MariX/BriXS project [1] , for kilovoltage rotational radiotherapy dedicated to the breast. Methods The proposed source is based...
2 CitationsSource
#1Giovanni Mettivier (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 22
#2Antonio Sarno (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 13
Last. Paolo Russo (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 24
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Purpose Measurements of the dose volume distribution in digital breast tomosynthesis (DBT) are lacking. They are useful for validation of Monte Carlo simulations in DBT dosimetry and also for devising models of radio-induced cancer risk in DBT exams. Due to the different scanner protocols (scan angle and spectra) the dose distribution can vary among DBT units and its determination is useful in scanner optimization and performance comparisons. We measured the dose volume distribution in breast ph...
1 CitationsSource
#1Giovanni Mettivier (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 22
#2Anton io Sarno (INFN: Istituto Nazionale di Fisica Nucleare)
Last. Paolo Russo (INFN: Istituto Nazionale di Fisica Nucleare)H-Index: 24
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Purpose Recently, we proposed the use of the synchrotron radiation (SR) beam for a new rotational radiotherapy technique for breast cancer treatment (SR3T) [1] ;. In this work, we show, via Monte Carlo (MC) simulations, the potential of SR3T also for application in breast radiosurgery with the patient in prone position. Methods We simulated the irradiation condition of the breast rotational radiosurgery with a MC code based on GEANT 4 toolkit. The pendant breast was modeled as a polyethylene cyl...
#1Antonio SarnoH-Index: 13
#2Giovanni MettivierH-Index: 22
Last. Paolo RussoH-Index: 24
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Abstract Purpose In cone-beam computed tomography dedicated to the breast (BCT), the mean glandular dose (MGD) is the dose metric of reference, evaluated from the measured air kerma by means of normalized glandular dose coefficients (DgNCT). This work aimed at computing, for a simple breast model, a set of DgNCT values for monoenergetic and polyenergetic X-ray beams, and at validating the results vs. those for patient specific digital phantoms from BCT scans. Methods We developed a Monte Carlo c...
13 CitationsSource
The principle of rotational summation of the absorbed dose for breast cancer treatment with orthovoltage X-ray beams was proposed by J. Boone in 2012. Here, use of X-ray synchrotron radiation for image guided external beam rotational radiotherapy treatment of breast cancer is proposed. Tumor irradiation occurs with the patient in the prone position hosted on a rotating bed, with her breast hanging from a hole in the bed, which rotates around a vertical axis passing through the tumor site. Horizo...
6 CitationsSource
#1Piernicola Oliva (University of Sassari)H-Index: 20
#2Bruno Golosio (University of Cagliari)H-Index: 24
Last. Renata Longo (UniTS: University of Trieste)H-Index: 26
view all 15 authors...
Iterative CT reconstruction algorithms coupled with edge-preserving filters are attracting a growing interest in the field of biomedical X-ray imaging. In many cases such algorithms demonstrate improved reconstruction quality compared with analytical reconstruction algorithms, for instance in the case of measurements with a reduced number of projections. Their performance is often evaluated on test phantoms using conventional figures of merit, as for example contrast-to-noise ratio or spatial re...
1 CitationsSource
#1Andrew W. Stevenson (CSIRO: Commonwealth Scientific and Industrial Research Organisation)H-Index: 29
#2Francesca Di LilloH-Index: 9
: It is shown that an extensive set of accurate ionization-chamber measurements with a primary polychromatic synchrotron X-ray beam transmitted through various filter combinations/thicknesses can be used to quite effectively estimate the absolute flux distribution. The basic technique is simple but the `inversion' of the raw data to extract the flux distribution is a fundamentally ill-posed problem. It is demonstrated, using data collected at the Imaging and Medical Beamline (IMBL) of the Austra...
5 CitationsSource
#1Antonio SarnoH-Index: 13
#2David R. Dance (University of Surrey)H-Index: 35
Last. Ioannis Sechopoulos (Radboud University Nijmegen)H-Index: 23
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PURPOSE: To characterize the dependence of normalized glandular dose (DgN) on various breast model and image acquisition parameters during spot compression mammography and other partial breast irradiation conditions, and evaluate alternative previously proposed dose-related metrics for this breast imaging modality. METHODS: Using Monte Carlo simulations with both simple homogeneous breast models and patient-specific breasts, three different dose-related metrics for spot compression mammography w...
17 CitationsSource