Baomei Zhang
Shandong University
Drug carrierNanomaterialsNanotechnologyNanocarriersPhotothermal therapyMaterials scienceIn vivoIncubationRed blood cellBiocompatibilityBiodistributionBiomaterialDrug deliveryHemolysisHematocritDoxorubicinDoxorubicin HydrochlorideHemolytic IndexGrapheneCentrifugation
4Publications
4H-index
149Citations
Publications 4
Newest
#1Baomei Zhang (SDU: Shandong University)H-Index: 4
#2Xiaoye Yang (SDU: Shandong University)H-Index: 2
Last. Guangxi Zhai (SDU: Shandong University)H-Index: 45
view all 4 authors...
Abstract A novel nanocarrier of heparin (Hep) modified graphene oxide (GO) was fabricated via a linker (adipic dihydrazide) and used as a pH-sensitive drug delivery system for controlling the release of anticancer drug doxorubicin (DOX) for anti-tumor therapy. The finally obtained nanocarrier was GO-ADH-Hep with better stability, blood compatibility and biocompatibility confirmed by the hemolytic test and in vitro cytotoxicity study. Its safety issue was greatly improved via Hep modification. Th...
24 CitationsSource
#1Baomei ZhangH-Index: 4
#2Yang WangH-Index: 4
Last. Guangxi Zhai (SDU: Shandong University)H-Index: 45
view all 4 authors...
Graphene-based nanomaterials have drawn abundant interest in various fields such as biomedicine in recent years. Thanks to the ultra-high surface area of single-layered graphene, higher molecular loading is obtained. In addition, easy modifications were acquired because of its ample oxygen-content functional groups. Owing to its excellent physical– chemical properties, graphene-based nanomaterials have been widely explored as novel nanovectors for disease theranostics. In this article, we gave a...
15 CitationsSource
#1Yang Wang (SDU: Shandong University)H-Index: 4
#2Baomei Zhang (SDU: Shandong University)H-Index: 4
Last. Guangxi Zhai (SDU: Shandong University)H-Index: 45
view all 3 authors...
The hemolysis assay is a common method used to evaluate the in vitro biocompatibility of biomaterials, but presently there is inadequate understanding of the interactions between RBCs and biomaterials, especially from the view of the incubation conditions and sample concentration. In this report, we used unmodified graphene oxide (GO) as a biomaterial model and measured the hemolytic properties of GO at a series of concentrations under multiple conditions, including medium type, red blood cell (...
7 CitationsSource
#1Baomei Zhang (SDU: Shandong University)H-Index: 4
#2Yang Wang (SDU: Shandong University)H-Index: 4
Last. Guangxi Zhai (SDU: Shandong University)H-Index: 45
view all 3 authors...
Abstract Graphene, a rapidly rising star, has gained extensive research interests lately due to its excellent properties—such as the exceptional optical, electrical, thermal and mechanical features—which are superior to other materials, so it is called “two-dimensional magical materials”. This article presents diverse types and various properties of graphene-based materials, and the current methods for the surface modifications of the graphene-based materials are briefly described. In addition, ...
99 CitationsSource