Pieter Martens
University of Hasselt
PathophysiologyInternal medicineSurgeryRenal functionCardiologyNatriuresisProspective cohort studyIntravascular volume statusVolume overloadSacubitril, ValsartanCardiac resynchronization therapySacubitrilValsartanIron deficiencyHeart failureKidney diseaseVentricular remodelingDiureticCreatinineLoop diureticIn patientAmbulatoryMedicineEjection fractionStroke volumeGastroenterology
93Publications
17H-index
874Citations
Publications 97
Newest
#1Pieter Martens (University of Hasselt)H-Index: 17
#2Jozine M. ter Maaten (UMCG: University Medical Center Groningen)H-Index: 25
Last. Wilfried Mullens (University of Hasselt)H-Index: 38
view all 9 authors...
Background: The heart failure (HF)-syndrome is associated with neuro-hormonal activation, chronic kidney disease (CKD), inflammation and alterations in the phosphorus-metabolism, all of which are i...
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#1Jeroen Dauw (University of Hasselt)H-Index: 7
#2Małgorzata Lelonek (Medical University of Łódź)H-Index: 17
Last. Wilfried MullensH-Index: 26
view all 32 authors...
AIMS Although acute heart failure (AHF) with volume overload is treated with loop diuretics, their dosing and type of administration are mainly based upon expert opinion. A recent position paper from the Heart Failure Association (HFA) proposed a step-wise pharmacologic diuretic strategy to increase the diuretic response and to achieve rapid decongestion. However, no study has evaluated this protocol prospectively. METHODS AND RESULTS The Efficacy of a Standardized Diuretic Protocol in Acute Hea...
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#1Jeroen Dauw (University of Hasselt)H-Index: 7
#2Matthias DupontH-Index: 17
Last. Wilfried Mullens (University of Hasselt)H-Index: 38
view all 5 authors...
Numerous patients with a cardiac implantable electronic device are admitted to the cardiac intensive care unit (ICU). When taking care of these patients, it is essential to have basic knowledge of potential device problems and how they could be tackled. This review summarizes common issues with pacemakers, implantable cardioverter-defibrillators, and cardiac resynchronization devices and provides a framework for troubleshooting in the ICU. In addition, specific aspects of intensive care that mig...
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#1Liesbeth F. Ghys (Novartis)
#2Pieter MartensH-Index: 17
Last. Michael Maris (Novartis)H-Index: 1
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Background: We conducted a nationwide survey to describe the in-and out-of-hospital flow (diagnosis, treatment and follow-up) of patients with heart failure with reduced ejection fraction (HFrEF).M...
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#1Pieter Martens (University of Hasselt)H-Index: 17
#2Jana KooijH-Index: 1
Last. Wilfried Mullens (University of Hasselt)H-Index: 38
view all 6 authors...
Background: Hyperkalaemia is a potentially life-threatening condition. Furthermore, it is one of the main reasons for discontinuation and dose reduction of renin-angiotensin-aldosterone system inhibitors (RAASi) in clinical practice. However, exact data on the prevalence and consequences of occurrence of hyperkalaemia when taking RAASi in a dedicated heart failure care setting are scarce.Methods: Consecutive patients diagnosed with heart failure from a single tertiary hospital between August 200...
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#1Pieter MartensH-Index: 17
#2Matthias DupontH-Index: 17
Last. Wilfried Mullens (University of Hasselt)H-Index: 38
view all 10 authors...
AIMS Iron deficiency is common in heart failure with reduced ejection fraction (HFrEF) and negatively affects cardiac function and structure. The study the effect of ferric carboxymaltose (FCM) on cardiac reverse remodelling and contractile status in HFrEF. METHODS AND RESULTS Symptomatic HFrEF patients with iron deficiency and a persistently reduced left ventricular ejection fraction (LVEF <45%) at least 6 months after cardiac resynchronization therapy (CRT) implant were prospectively randomize...
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#1Pieter MartensH-Index: 17
#2Lieven HerbotsH-Index: 25
Last. Jan Verwerft (University of Hasselt)H-Index: 1
view all 7 authors...
Little data is available about the pathophysiological mechanisms of unexplained dyspnea and their clinical meaning. Consecutive patients with unexplained dyspnea underwent prospective standardized cardiopulmonary exercise testing with echocardiography (CPETecho). Patients were grouped as having normal exercise capacity (peak VO2 > 80% with respiratory exchange [RER] > 1.05), reduced exercise capacity (peak VO2 ≤ 80% with RER > 1.05), or a submaximal exercise test (RER ≤ 1.05). From 307 patients,...
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BACKGROUND Contemporary data on left ventricular function (LVF) recovery in patients with left ventricular dysfunction after ST-elevation myocardial infarction (STEMI) are scarce and to date, no comparison has been made with patients with a baseline normal LVF. This study examined predictors of LVF recovery and its relation to outcomes in STEMI. METHODS Patients presenting with STEMI between January 2010 and December 2016 were categorized in three groups after 3 months according to left ventricu...
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#1Pierpaolo Pellicori (Glas.: University of Glasgow)H-Index: 25
#2Elke Platz (Brigham and Women's Hospital)H-Index: 24
Last. Nicolas Girerd (University of Lorraine)H-Index: 32
view all 13 authors...
Congestion, related to pressures and/or fluid overload, plays a central role in the pathophysiology, presentation and prognosis of heart failure and is an important therapeutic target. While symptoms and physical signs of fluid overload are required to make a clinical diagnosis of heart failure, they lack both sensitivity and specificity, which might lead to diagnostic delay and uncertainty. Over the last decades, new ultrasound methods for the detection of elevated intracardiac pressures and/or...
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