Joan Torras
Polytechnic University of Catalonia
Protein subunitSelf-healing hydrogelsGlycoproteinHydrogen bondBiophysicsConductive polymerFabricationMonomerNanotechnologyHistone octamerInorganic chemistryAqueous solutionChemistryPolymer chemistryMaterials scienceSteric effectsQuantum chemistryVirusOxalatePolypyrroleBiopolymerCarboxylic acidSide reactionPeptideSubstrate (printing)Material selectionResidue (chemistry)Oxalic acidFuture studiesSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Highly porousBiodegradable scaffoldLiterature surveyMolecular mechanismPeptide bondMoleculeCounterionTopology (chemistry)Chemical engineeringPolymerizationBiodegradable polymerTissue engineeringPolymerThixotropyMolecular dynamicsProtein secondary structureStereochemistry
Publications 5
#1Reza Zeinali (UPC: Polytechnic University of Catalonia)H-Index: 1
#2Luis J. del Valle (UPC: Polytechnic University of Catalonia)H-Index: 27
Last. Jordi Puiggalí (UPC: Polytechnic University of Catalonia)H-Index: 39
view all 4 authors...
Porous biodegradable scaffolds provide a physical substrate for cells allowing them to attach, proliferate and guide the formation of new tissues. A variety of techniques have been developed to fabricate tissue engineering (TE) scaffolds, among them the most relevant is the thermally-induced phase separation (TIPS). This technique has been widely used in recent years to fabricate three-dimensional (3D) TE scaffolds. Low production cost, simple experimental procedure and easy processability toget...
#1Didac MartíH-Index: 1
#2Joan Torras (UPC: Polytechnic University of Catalonia)H-Index: 3
Last. Carlos Alemán (UPC: Polytechnic University of Catalonia)H-Index: 56
view all 5 authors...
Recent studies have shown that SARS-CoV-2 virus can be inactivated by effect of heat, even though, little is known about the molecular changes induced by the temperature. Here, we unravel the basics of such inactivation mechanism over the SARS-CoV-2 spike glycoprotein by executing atomistic molecular dynamics simulations. Both the closed down and open up states, which determine the accessibility to the receptor binding domain, were considered. Results suggest that the spike undergoes drastic cha...
#1Marco CrismaH-Index: 56
#2Fernando FormaggioH-Index: 52
Last. Claudio TonioloH-Index: 79
view all 8 authors...
The intramolecularly H-bonded, fully-extended conformation (C-5) of an alpha-amino acid residue (and the resulting 2.0(5)-helix obtained via its propagation) is one of the least extensively investigated types of peptide and protein backbone secondary structure. This situation does still currently occur despite its unique ability to enjoy by far the largest separation per residue among peptide conformations. In this article, we offer a detailed update of our present knowledge on this intriguing 3...
4 CitationsSource
#2Joan TorrasH-Index: 3
Last. David DíazH-Index: 58
view all 6 authors...
This manuscript describes a new route to prepare rapidly Ca2+-free hydrogels from unmodified sodium alginate by simply mixing with small organic molecules such as poly(carboxylic acid) compounds as cross-linker agents instead of classical divalent metal salts such as CaCl2. Dimethyl sulfoxide (DMSO) was also found to induce the rapid gelation of aqueous alginate solutions. The gelation process takes place at room temperature, and depending on the composition, gels with good thermal (90–100 °C) a...
18 CitationsSource
#1Carlos Alemán (UPC: Polytechnic University of Catalonia)H-Index: 56
#2Jordi CasanovasH-Index: 26
Last. Francesc Estrany (UPC: Polytechnic University of Catalonia)H-Index: 23
view all 7 authors...
Abstract A comparative study about cross-linking in electrogenerated polypyrrole and poly( N -methylpyrrole) is presented. Experimental studies on polymer films prepared under a constant potential of 1.4 V but considering different polymerization times as well as quantum mechanical calculations on model oligomers indicated that cross-linking is very low in polypyrrole, while cross-links are frequently formed by poly( N -methylpyrrole) chains. These behaviors have been attributed to the architect...
26 CitationsSource