Alessandro Cicchetti
University of Pavia
CancerInternal medicineRadiologyUrologyOncologyChemotherapyFecal incontinenceAbdominal surgeryProstate cancerPopulationUrinary symptomsToxicityNuclear medicineNasopharyngeal cancerRadical radiotherapyIn patientCancer researchRadiation therapyMedicineCohortUrinary system
62Publications
7H-index
106Citations
Publications 62
Newest
#1Sara RonchiH-Index: 10
#2Barbara VischioniH-Index: 14
Last. Ester OrlandiH-Index: 22
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#1Luca Possenti (Polytechnic University of Milan)H-Index: 4
Last. Paolo Zunino (Polytechnic University of Milan)H-Index: 28
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We address a mathematical model for oxygen transfer in the microcirculation. The model includes blood flow and hematocrit transport coupled with the interstitial flow, oxygen transport in the blood and the tissue, including capillary-tissue exchange effects. Moreover, the model is suited to handle arbitrarily complex vascular geometries. The purpose of this study is the validation of the model with respect to classical solutions and the further demonstration of its adequacy to describe the heter...
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#1Luca Possenti (Polytechnic University of Milan)H-Index: 4
Last. Matteo MorettiH-Index: 31
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Ionizing radiation (IR) is used in radiotherapy as a treatment to destroy cancer. Such treatment also affects other tissues, resulting in the so-called normal tissue complications. Endothelial cells (ECs) composing the microvasculature have essential roles in the microenvironment’s homeostasis (ME). Thus, detrimental effects induced by irradiation on ECs can influence both the tumor and healthy tissue. In-vitro models can be advantageous to study these phenomena. In this systematic review, we an...
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BACKGROUND This study analyzes patient health-related quality of life (QoL) 24-month after prostate cancer (PCa) diagnosis within the PROState cancer monitoring in ITaly from the National Research Council (Pros-IT CNR) study. METHODS Pros-IT CNR is an ongoing, longitudinal and observational study, considering a convenience sample of patients enrolled at PCa diagnosis and followed at 6, 12, 24, 36, 48 and 60 months from the diagnosis. Patients were grouped according to the treatment received: ner...
1 CitationsSource
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#2Tiziana RancatiH-Index: 27
Last. R. ValdagniH-Index: 4
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#1A. CavalloH-Index: 7
#2Tiziana RancatiH-Index: 27
Last. E. OrlandiH-Index: 3
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#1Tim Rattay (University of Leicester)H-Index: 9
#2Petra Seibold (DKFZ: German Cancer Research Center)H-Index: 27
Last. Sheryl GreenH-Index: 18
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Background: Acute skin toxicity is a common and usually transient side-effect of breast radiotherapy although, if sufficiently severe, it can affect breast cosmesis, aftercare costs and the patient's quality-of-life. The aim of this study was to develop predictive models for acute skin toxicity using published risk factors and externally validate the models in patients recruited into the prospective multi-center REQUITE (validating pREdictive models and biomarkers of radiotherapy toxicity to red...
1 CitationsSource
#1Michela Carlotta Massi (Polytechnic University of Milan)H-Index: 2
#2Francesca Gasperoni (Medical Research Council)H-Index: 1
Last. Tiziana RancatiH-Index: 27
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Background: REQUITE (validating pREdictive models and biomarkers of radiotherapy toxicity to reduce side effects and improve QUalITy of lifE in cancer survivors) is an international prospective cohort study. The purpose of this project was to analyse a cohort of patients recruited into REQUITE using a deep learning algorithm to identify patient-specific features associated with the development of toxicity, and test the approach by attempting to validate previously published genetic risk factors....
2 CitationsSource
Objective: This study aimed to look into the relationship between intensity-modulated-radiotherapy (IMRT)- or volumetric-modulated-arc-therapy (VMAT)-based dose-volume parameters and 5-year outcome for a consecutive series of non-metastatic nasopharyngeal cancer (NPC) patients (pts) treated in a single institution in a non-endemic area in order to identify potential prognostic factors. Materials and methods: A retrospective analysis of consecutive non-metastatic NPC pts treated curatively with I...
2 CitationsSource