Jianjun Dong
Shandong University
Internal medicineEndocrinologyOdds ratioRandomized controlled trialChemistryApoptosisType 2 diabetesRestenosisInsulinThyroid cancerDiabetic nephropathyMetforminSodium-iodide symporterThyroid carcinomaCancer researchThyroidDiabetes mellitusMedicineGastroenterologyMeta-analysis
62Publications
11H-index
326Citations
Publications 62
Newest
#1Rui Zhang (SDU: Shandong University)H-Index: 7
#2Xiaojun Zhou (SDU: Shandong University)H-Index: 6
Last. Lin Liao (SDU: Shandong University)H-Index: 12
view all 9 authors...
Gliquidone was suggested to exert hypoglycemic effect through enhancing hepatic insulin sensitivity. However, inadequate in vivo evidences make this statement controversial. The aim of the present study was to clarify the insulin-sensitizer role of gliquidone in liver and muscle, so as to confirm its extra-pancreatic effects in vivo. TALEN technique was used to create Sur1 knockout (Sur1-/-) rats. Diabetic Sur1-/- rat models were established by high-fat diet combined with streptozotocin, and whi...
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#1Xianzhi Li (SDU: Shandong University)
Last. Lin Liao (SDU: Shandong University)H-Index: 12
view all 9 authors...
AIMS To investigate the efficacy and safety of SGLT-2 inhibitors as an add-on treatment for metformin between Asian and non-Asian T2DM. METHODS A systematic literature search of PubMed, EMBASE, and the Cochrane Library was performed through August 2020 with the following keywords: Sodium-Glucose Transporter 2 Inhibitors, Sodium Glucose Transporter 2 Inhibitors, SGLT2 inhibitor, SGLT-2 inhibitors, type 2 diabetes, and randomized controlled trials. Double-blinded RCTs comparing SGLT-2 inhibitors a...
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#1Yuying Cui (SDUTCM: Shandong University of Traditional Chinese Medicine)
Last. Liao Lin (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 1
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The objective of this study is to summarize the clinical and pathologic characteristics of malignant struma ovarii to facilitate the early diagnosis and treatment of this disease. All 144 patients were females from 27 countries. The mean age of the patients at diagnosis was 42.6 years. Overall, 35.71% of the patients underwent unilateral oophorectomy, 58.57% of the patients underwent bilateral oophorectomy, 5.72% of the patients were not ovariectomized, and 38.57% of the patients received radioa...
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#1Junyu ZhaoH-Index: 7
Last. Jianjun DongH-Index: 11
view all 8 authors...
Background Hyperlipidemia has been hypothesized as a risk factor for thyroid cancer. However, the association between hypercholesterolemia and thyroid cancer is unclear, especially in Chinese population without available published data. We conducted this study to investigate the relationship between hypercholesterolemia and differentiated thyroid cancer (DTC) in Chinese population. Methods Three thousand seven hundred forty-eight patients were enrolled in the study, including 2,021 DTC patients ...
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Purpose The conventional interventions of anaplastic thyroid carcinoma (ATC) patients are mainly through surgery, chemotherapy, and radiotherapy; however, it is hardly to improve survival rate. We aimed to investigate the differential expressed genes (DEGs) between ATC and normal thyroid gland through bioinformatics analysis of the microarray datasets and find new potential therapeutic targets for ATC. Methods Microarray datasets GSE9115, GSE29265, GSE33630, GSE53072, and GSE65144 were downloade...
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#1Chunmei Xu (SDU: Shandong University)H-Index: 3
Last. Jianjun Dong (SDU: Shandong University)H-Index: 11
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A potential reduction of goiter volume (GV) of recombinant human thyrotropin (rhTSH) on multinodular goiters (MNG) was previously reported but controversial. Hence we conducted a meta-analysis to estimate the effect of rhTSH-stimulated radioiodine therapy in patients with MNG. PubMed, Cochrane, CNKI, VIP, and Wanfang databases were searched. Mean difference (MD) and odds ratios with 95% confidence intervals (95% CI) were derived by using an inverse variance random-effects model and fixed-effects...
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#1Zhiwei Zou (Binzhou University)H-Index: 3
#2Xiaojun Zhou (SDU: Shandong University)H-Index: 6
Last. Jianjun Dong (SDU: Shandong University)H-Index: 11
view all 14 authors...
To explore the potential role of Lin28a in the development of restenosis after percutaneous transluminal angioplasty, double-balloon injury surgery and mono-balloon injury surgery were used to establish restenosis and atherosclerosis models, respectively, so as to better distinguish restenosis from atherosclerotic lesions. Immunohistochemical analysis revealed that significantly higher expression of Lin28a was observed in the iliac arteries of restenosis plaques than that of atherosclerosis plaq...
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#1Junyu Zhao (SDU: Shandong University)H-Index: 7
#2Jing Wen (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 1
Last. Jianjun Dong (SDU: Shandong University)H-Index: 11
view all 6 authors...
The incidence of thyroid carcinoma is increasing all over the world. Some studies have suggested that the change of adipokines expression can induce thyroid carcinoma. However, other studies have come to the opposite conclusion. Therefore, we studied the relationship between adipokines and thyroid carcinoma. Databases—PubMed, Cochrane Library, SinoMed, CNKI, Wanfang, and clinical trial registries were searched. A meta-analysis was then performed through a fixed or random-effects model to calcula...
1 CitationsSource
#1Yuhan Zhang (SDU: Shandong University)H-Index: 2
#2Xianzhi Li (SDU: Shandong University)
Last. Lin Liao (SDU: Shandong University)H-Index: 12
view all 5 authors...
Thyroid-associated ophthalmopathy (TAO) is an autoimmune inflammatory disorder, which lacks effective treatment currently. Spica Prunellae (SP) is popularly used for its anti-inflammatory and immune-regulating properties, indicating SP may have potential therapeutic value in TAO. Therefore, the purpose of this study is to identify the efficiency and potential mechanism of SP in treating TAO. A network pharmacology integrated molecular docking strategy was used to predict the underlying molecular...
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#1Yuhan Zhang (SDU: Shandong University)H-Index: 2
#2Tian CaiH-Index: 1
Last. Lin Liao (SDUTCM: Shandong University of Traditional Chinese Medicine)H-Index: 12
view all 8 authors...
Non-alcoholic fatty liver disease (NAFLD) is currently the most common cause of chronic liver disease. However, the treatment is limited. The aim of this meta-analysis was to evaluate the effects and safety of sitagliptin, a selective inhibitor of dipeptidyl peptidase-4 (DPP-4I), in treating NAFLD. Studies were sourced from electronic databases including PubMed, CENTRAL (Cochrane Controlled Trials Register), Embase, Medline, Web of Science, Clinical Trials, and CNKI to identify all randomized co...
1 CitationsSource