Chirag C. Sheth
CEU Cardinal Herrera University
Internal medicineSurgeryCorpus albicansCardiologyChemistryDentistryImmunologyDiospyros kakiSirolimusStentCytokineCandida albicansAerobic bacteriaIn patientN-linked glycosylationBrowningMedicineBiologyMicrobiologyGastroenterology
Publications 40
BACKGROUND: More than 90% of malignant tumors of the head and neck are oral squamous cell carcinomas. Early detection of oral squamous cell carcinoma using salivary biomarkers could prevent malignant transformations and enhance patient survival. METHODS: A systematic search in MEDLINE and the Central Register of Controlled Trials and meta-analysis were undertaken to identify the screening potential of six salivary biomarkers for early oral squamous cell carcinoma detection: interleukins IL-8 and...
4 CitationsSource
BACKGROUND In the era of antimicrobial resistance, fungal pathogens are not an exception. Several strategies, including antimicrobial stewardship programs and high throughput screening of new drugs are being implemented. Several recent studies have demonstrated effectiveness of plant compounds with antifungal activity. OBJECTIVE In this systematic review we examine the use of natural compounds as a possible avenue to fight fungal infections produced by Candida albicans, the most common human fun...
#1Vardhmaan Jain (Cleveland Clinic)H-Index: 5
#2Vikram Sharma (Cleveland Clinic)H-Index: 12
Last. Maan Fares (Cleveland Clinic)H-Index: 2
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Background: Post-transplant major adverse cardiovascular events (MACE) are amongst the leading cause of death amongst orthotopic liver transplant(OLT) recipients. Despite years of guideline directe...
#1Chirag C. Sheth (Cleveland Clinic)H-Index: 11
#1Chirag Sheth (Cleveland Clinic)
Last. John R. Bartholomew (Cleveland Clinic)H-Index: 21
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Heparin-induced thrombocytopenia (HIT) is an immune-mediated adverse reaction to heparin which can cause life-threatening venous as well as arterial thrombosis. HIT-driven thrombosis is associated with very high morbidity and mortality. Patients with HIT are also at increased risk of bleeding due to concomitant use of non-heparin anticoagulant, especially in patients with profound thrombocytopenia. We present a case of a 69-year-old female who developed heparin-induced thrombocytopenia complicat...
#1Veronica VesesH-Index: 8
Last. Chirag C. ShethH-Index: 11
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Extrinsic black dental staining is an external dental discoloration of bacterial origin, considered a special form of dental plaque. Currently, there is no definitive therapeutic option for eliminating black stain. This study employed 16S rRNA metagenomics to analyze black stain and white-plaque samples from 27 adult volunteers. Study objectives were to: describe the microbial diversity of adult black stain samples; characterize their taxonomic profile; compare the microbiomes of black stain ver...
#1Michael Tran (Cleveland Clinic)H-Index: 1
#2Chirag C. Sheth (Cleveland Clinic)H-Index: 11
Last. Deborah Hornacek (Cleveland Clinic)H-Index: 3
view all 5 authors...
Patients infected with SARS-CoV-2 often develop venous and arterial thrombosis. The high patient mortality is partly attributed to thrombotic events. An emerging trend is the presence of immunological phenomena including antiphospholipid antibodies which may promote thrombosis. The mechanism for these observations is not clear though many patients with SARS-CoV-2 develop thrombocytopenia. We describe a patient with SARS-CoV-2 pneumonitis who presented with intermediate risk pulmonary embolism (P...
2 CitationsSource
#1Chirag C. Sheth (Cleveland Clinic)H-Index: 11
#1Chirag Sheth (Cleveland Clinic)
Last. Deborah Hornacek (Cleveland Clinic)H-Index: 3
view all 2 authors...
Heparin induced thrombocytopenia (HIT) has been rarely reported in patients with essential thrombocytosis (ET). Precise diagnosis requires high index of suspicion due to elevated platelet count in patients with ET. A 73 year old male patient was admitted for acute exacerbation of heart failure with
BACKGROUND: Resistance to antimicrobial agents has become a problem in modern society. Antibiotic resistant bacteria undermine the prevention and treatment of infections. Undergraduate dental students in Europe are required to receive information in aspects of microbiology relevant for dental practice, including oral microbial pathogens and resistance mechanisms against antimicrobial compounds. The objective of this study was to implement a research-based strategy to aid the understanding of the...
1 CitationsSource
#1Luca TestaH-Index: 44
#2Sameer Dani (Care Institute of Medical Sciences)H-Index: 8
Last. Dinesh Shah (Beaumont Hospital)H-Index: 2
view all 9 authors...
Patients with diabetes mellitus (DM) have poorer outcomes after percutaneous coronary intervention than those without diabetes. We evaluate the 2-year safety and efficacy profile of the Abluminus DES+ in patients with diabetes within the population enrolled in the large multicenter en-ABL e-registry