Rong Tang
Guangzhou University of Chinese Medicine
CancerMolecular biologyK562 cellsHigh-performance liquid chromatographyChemistryMesenchymal stem cellIn vivoChemosensitizerDosingPaclitaxelHeLaCajanusFlavonoidBone marrowToxicityBiochemistryTraditional medicineCell growthCell culturePharmacology
Publications 3
#1Rong Tang (Guangzhou University of Chinese Medicine)H-Index: 3
#2Ru-Hua Tian (Guangzhou University of Chinese Medicine)H-Index: 3
Last. Ying-Jie Hu (Guangzhou University of Chinese Medicine)H-Index: 6
view all 6 authors...
AbstractContext: The leaves of Cajanus cajan (L.) Millsp. (Fabaceae) have diverse bioactivities, but little safety data are reported.Objective: This study examines the toxicological profiles of C. cajan leaf extracts.Materials and methods: The leaves were extracted by water or 90% ethanol to obtain water or ethanol extract (WEC or EEC). EEC was suspended in water and successively fractionated into dichloroform and n-butanol extracts (DEC and BEC). Marker compounds of the extracts were monitored ...
6 CitationsSource
#1Jia-Zhong CaiH-Index: 4
#2Rong TangH-Index: 3
Last. Xiao-Ling ShenH-Index: 7
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A new natural halogen-containing stilbene derivative was isolated from the leaves of Cajanus cajan (L.) Millsp. and identified as 3-O-(3-chloro-2-hydroxyl-propanyl)-longistylin A by comprehensive spectroscopic and chemical analysis, and named cajanstilbene H (1). It is the first halogen-containing stilbene derivative found from plants. In human mesenchymal stem cells (hMSC) from bone marrow, 1 did not promote cell proliferation, but distinctly enhanced osteogenic differentiation of hMSC in time-...
6 CitationsSource
#1Rui-Jing ZhuH-Index: 1
#2Xiao-Ling ShenH-Index: 7
Last. Ying-Jie Hu (Guangzhou University of Chinese Medicine)H-Index: 3
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Marsdeniae tenacissimae Caulis (MTC) is a Chinese herbal medicine used mainly for treatment of cancer, whose pharmacologically active constituents responsible for its in vivo activity and clinical efficacy have not been clearly elucidated. In this study, total aglycones of MTC (ETA) showed the ability to sensitize KB-3-1, HeLa, HepG2 and K562 cells to paclitaxel treatment. More inspiringly, ETA markedly enhanced the antitumor activity of paclitaxel in nude mice bearing HeLa or KB-3-1 xenografts....
14 CitationsSource
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