Ying Shao
Internal medicineEndocrinologySurgerySensory nerveSubstance PNerve fiberStreptozotocinWound healingType I collagenStem cellMedicineEpidermis (botany)
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#1Fei-bin Zhu (NCU: Nanchang University)H-Index: 1
#2Xiang-jing FangH-Index: 1
Last. De-ming Liu (NCU: Nanchang University)H-Index: 4
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Exogenous substance P accelerates wound healing in diabetes, but the mechanism remains poorly understood. Here, we established a rat model by intraperitoneally injecting streptozotocin. Four wounds (1.8 cm diameter) were drilled using a self-made punch onto the back, bilateral to the vertebral column, and then treated using amniotic membrane with epidermal stem cells and/or substance P around and in the middle of the wounds. With the combined treatment the wound-healing rate was 100% at 14 days....
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