Jerzy Mosiewicz
Medical University of Lublin
Internal medicineRadiologyEndocrinologyGenotypeSurgeryPathologyDermatologyCardiologyIntensive care medicineImmunologyObstructive sleep apneaHeart failureDiseasePathogenesisIn patientMyocardial infarctionObesityDiabetes mellitusMedicineBlood pressureGastroenterology
208Publications
12H-index
496Citations
Publications 208
Newest
Background and Objectives: Microcirculation dysfunction is present in patients with obstructive sleep apnea (OSA). Intermittent hypoxia generates “oxidative stress”, which contributes to chronic inflammation. The secretion of nitric oxide (NO), which is responsible for adequate regulation of the endothelium, is impaired due to a decrease in endothelial nitric oxide synthetase (eNOS) expression and an increase in endogenous eNOS inhibitors. Furthermore, nocturnal awakenings lead to the dysregulat...
2 CitationsSource
#1Wojciech Myslinski (Medical University of Lublin)H-Index: 4
#2Agata Rękas-Wójcik (Medical University of Lublin)H-Index: 2
Last. Jerzy Mosiewicz (Medical University of Lublin)H-Index: 12
view all 9 authors...
Objective. The objective of the study was to compare polygraphic parameters and selected laboratory parameters in patients with obstructive sleep apnoea (OSA) who develop various types of left ventricular (LV) geometry. Material and Methods. The research covered 122 patients with obstructive sleep apnoea and coexisting effectively treated systemic hypertension (95 men, 27 women, average age: ). Overnight polygraphy, echocardiography, carotid artery ultrasonography, and laboratory measurements we...
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INTRODUCTION Alcohol consumption causes acute and chronic liver injury. The clinical forms of alcohol liver disease (ALD) include steatosis, hepatitis, cirrhosis, and hepatocellular carcinoma (HCC) associated with liver cirrhosis. OBJECTIVE The aim of the study was to determine the levels of novel markers of fibrogenesis and angiogenesis in patients with alcoholic liver cirrhosis. Serum levels of angiopoietin-like peptide 4 (ANGPTL-4), asialoglycoprotein receptor 1 (ASGP-R1), and S100 calcium-bi...
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#1Malgorzata Dec-Gilowska (Medical University of Lublin)H-Index: 1
#2Marcin Trojnar (Medical University of Lublin)H-Index: 7
Last. Jerzy Mosiewicz (Medical University of Lublin)H-Index: 12
view all 6 authors...
ObjectiveArterial elasticity is important for assessing the state of an artery. This cross-sectional study aimed to non-invasively examine stiffness parameters of the ascending aorta in patients wi...
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#1Wojciech Myslinski (Medical University of Lublin)H-Index: 4
#2Agata Stanek (Medical University of Silesia)H-Index: 16
Last. Jerzy Mosiewicz (Medical University of Lublin)H-Index: 12
view all 4 authors...
Objective The objective of our study was to evaluate the incidence of target organ damages (TOD) in patients with arterial hypertension and the first ever episode of myocardial infarction (N-STEMI or STEMI) and to determine which of the analyzed kinds of TOD had the highest predictive value for the assessment of the likelihood of acute coronary syndrome (ACS). Material and Methods. The study group consisted of 51 patients with treated systemic hypertension, suffering from the first episode of my...
3 CitationsSource
INTRODUCTION: Diagnostic procedure in Coronavirus Disease 2019 (COVID-19) is based mainly on performing real-time-reverse transcription-polymerase chain-reaction (RT-PCR), which has been accepted as the gold standard method. In some cases, such as mutations of the SARS-CoV-2 genome, variable viral load kinetics or laboratory errors, it can be false-negative. CASE REPORT: The case is presented of a 56-year-old man with respiratory tract symptoms, with twice negative results of real-time-reverse t...
1 CitationsSource
#1Malgorzata Dec-Gilowska (Medical University of Lublin)H-Index: 1
#2Marcin Trojnar (Medical University of Lublin)H-Index: 7
Last. Jerzy Mosiewicz (Medical University of Lublin)H-Index: 12
view all 8 authors...
Background and objectives: Diabetes mellitus represents a metabolic disorder the incidence of which has been on the increase in recent years. The well-known long-term complications of this disease encompass a wide spectrum of renal, neurological and cardiovascular conditions. The aim of the study was to investigate the serum concentration of endothelial microparticles (EMPs) as well as selected noninvasive parameters of the ascending aorta stiffness calculated with echocardiography. Materials an...
1 CitationsSource
#1Sylwia Przybylska-Kuć (Medical University of Lublin)H-Index: 3
#2Maciej Zakrzewski (Medical University of Lublin)H-Index: 3
Last. Jerzy Mosiewicz (Medical University of Lublin)H-Index: 12
view all 9 authors...
Objectives Amyloid-β 1–40 (Aβ 1–40) and amyloid-β 1–42 (Aβ 1–42) are the proteins known to be involved in the pathogenesis of Alzheimer’s disease (AD)–the most common cause of dementia in the elderly. Hypoxia is suspected to be one of conditions associated with Aβ plasma level increase. A common reason of hypoxia is obstructive sleep apnea (OSA), characterized by recurrent episodes of apnea. Aim The aim of the study was to evaluate plasma Aβ 1–40 and Aβ 1–42 concentrations in patients with OSA. ...
12 CitationsSource
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Background and objectives: Data concerning vaspin in obstetric aspects are limited and conflicting. The aim of the study was to evaluate vaspin concentrations in the serum and urine of women with excessive gestational weight gain (EGWG) in the early post-partum period (i.e., 48 h after delivery), when placental function no longer influences the results. Materials and Methods: The study subjects were divided into two groups of 28 healthy controls and 38 mothers with EGWG. Maternal body compositio...
2 CitationsSource