Constanza Martínez
Pontifical Catholic University of Chile
Simulated body fluidInternal medicinePathologyPeriodontologyCellular differentiationCellMatrix (biology)ChemistryPediatricsExtracellular matrixMaterials scienceMesenchymal stem cellImmunologyMyofibroblastGrowth factorGranulation tissueSonic hedgehogInflammationArthritisPeriodontiumMethylglyoxalPlatelet-poor plasmaArthropathyMalaiseTravel medicinePeriodontal ligament stem cellsPlatelet-rich plasmaWound healingFibroblastAngiogenesisHeadachesChikungunyaStem cellPeriodontal diseasePeriodontal tissueCancer researchConnective tissueViability assayDiabetes mellitusBioinformaticsCell growthMedicineFibronectinBiologyPlateletCell biology
26Publications
12H-index
381Citations
Publications 26
Newest
#1Patricio C. Smith (UC: Pontifical Catholic University of Chile)H-Index: 22
#2Ignacio N. Retamal (UC: Pontifical Catholic University of Chile)H-Index: 6
Last. Constanza Martínez (UC: Pontifical Catholic University of Chile)H-Index: 12
view all 7 authors...
Resumen Diabetes y enfermedad periodontal corresponden probablemente al mejor ejemplo de como una enfermedad sistemica puede tener un efecto en el territorio periodontal. Si bien esta asociacion ha sido extensamente estudiada, muchas de las asociaciones propuestas presentan contradicciones. En la presente revision de la literatura se analizan los siguientes topicos relevantes para la practica clinica en periodoncia e implantologia: i) Identificacion de enfermedad periodontal severa y su capacida...
2 CitationsSource
#1Francisco Valenzuela (University of Chile)H-Index: 14
#2Cristian Covarrubias (University of Chile)H-Index: 15
Last. Mehrdad Yazdani-Pedram (University of Chile)H-Index: 29
view all 6 authors...
Bionanocomposites based on ceramic nanoparticles and a biodegradable porous matrix represent a promising strategy for bone repair applications. The preparation and bioactive properties of bionanocomposites based on hydroxyapatite (nHA) and bioactive glass (nBG) nanoparticles were presented. nHA and nBG were synthesized with nanometric particle size using sol–gel/precipitation methods. Composite scaffolds were prepared by incorporating nHA and nBG into a porous alginate (ALG) matrix at different ...
27 CitationsSource
#1Patricio C. Smith (UC: Pontifical Catholic University of Chile)H-Index: 22
#2Ignacio N. Retamal (UC: Pontifical Catholic University of Chile)H-Index: 6
Last. Constanza Martínez (UC: Pontifical Catholic University of Chile)H-Index: 12
view all 7 authors...
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#2Ignacio N. RetamalH-Index: 6
Last. Constanza MartínezH-Index: 12
view all 7 authors...
Diabetes and periodontal disease correspond to conditions that probably exemplify how a systemic disease may have a strong impact in the periodontium. Although this association has been studied for several years, many of these studies still show contradictory results. The present review analyses the following questions relevant for the clinician in the fields of periodontology: i) Value of the diagnosis of severe periodontitis and its capacity to identify previously un-diagnosed cases of diabete...
#1Constanza Martínez (University of Chile)H-Index: 12
#2Patricio C. SmithH-Index: 22
Last. Verónica PalmaH-Index: 21
view all 4 authors...
Regulation of cell renewal in the periodontium is a critical cell function that has not been clarified. Sonic hedgehog (Shh) is a secreted signaling molecule that plays a key role during development and adult tissue homeostasis. In the present study, we have analyzed the role played by Shh in human periodontal ligament stem cell (HPLSC) proliferation. HPLSC were isolated with anti-STRO-1 antibodies. Shh increased the expression of GLI1 and PTC-1 and selectively stimulated cell proliferation in S...
22 CitationsSource
#1Katrina Müller (University of Chile)H-Index: 1
#2Cristian Figueroa (University of Chile)H-Index: 7
Last. Remigio López-Solís (University of Chile)H-Index: 17
view all 9 authors...
Abstract The volume of saliva in the mouth of sensory panelists was measured by a dilution assay using a freshly prepared beetroot extract as probe solution. An aliquot of the extract absorbing linearly at 531-nm (probe) was placed in the mouth, mixed with saliva and returned to a clean container within a period of time shorter than the one spanning a single swallowing cycle. Beetroot pigments were neither partitioned into sub-fractions of saliva nor affected spectroscopically by their mixing wi...
13 CitationsSource