Marco Perna
University of Florence
Internal medicineRadiologySurgeryOncologyUnivariate analysisRetrospective cohort studyStage (cooking)Medical physicsAdverse effectHazard ratioMetastatic breast cancerLung cancerSurvival rateChemotherapyImmunotherapyLungCommon Terminology Criteria for Adverse EventsStandard treatmentSoft tissue sarcomaConcomitantNivolumabRadiosurgeryTargeted therapyToxicityStereotactic body radiotherapyLocally advancedIn patientStage ivRetrospective analysisCancer researchRadiation therapyBreast cancerMedicine
36Publications
5H-index
77Citations
Publications 36
Newest
#1Marco Perna (UniFI: University of Florence)H-Index: 5
#2Vieri Scotti (UniFI: University of Florence)H-Index: 19
Last. Alessio BruniH-Index: 15
view all 26 authors...
ABSTRACT Introduction : In this observational, retrospective, multi-center study, we aim to assess the safety of the combination of local metastasis-directed radiotherapy (RT) and immunotherapy in a cohort of advanced NSCLC (aNSCLC) patients. Material and Methods : We collected clinical data of aNSCLC patients who received concomitant RT and anti-PD1/PD-L1 inhibitors in seven Italian centers from September 2015 to June 2019. Concomitant RT was defined as delivered ≤4 weeks before or after the fi...
Source
#1Silvia ScocciantiH-Index: 19
#2Marco PernaH-Index: 5
Last. Lorenzo LiviH-Index: 28
view all 19 authors...
In case of circumscribed recurrent glioblastoma (rec-GBM), a second surgery (Re-S) and reirradiation (Re-RT) are local strategies to consider. The aim is to provide an algorithm to use in the daily clinical practice. The first step is to consider the life expectancy in order to establish whether the patient should be a candidate for active treatment. In case of a relatively good life expectancy (>3 months) and a confirmed circumscribed disease(i.e. without multiple lesions that are in different ...
Source
#1Andrea CameriniH-Index: 21
#2A. Del ConteH-Index: 2
Last. Domenico AmorosoH-Index: 23
view all 13 authors...
Source
Source
#1Silvia Scoccianti (UniFI: University of Florence)H-Index: 19
#2Gabriele Simontacchi (UniFI: University of Florence)H-Index: 18
Last. Lorenzo Livi (UniFI: University of Florence)H-Index: 28
view all 23 authors...
Purpose To determine dose constraints that correlate with alopecia in patients treated with photon-based Volumetric Modulated Arc Therapy (VMAT) for primary brain tumors. Methods During the treatment planning process, the scalp was drawn as a region of interest. Dose received by 0.1 cc (D0.1cc), mean dose (Dmeanscalp), volumes receiving different doses (V16Gy, V20Gy, V25Gy, V30Gy, V35Gy, V40Gy, and V43Gy) were registered for the scalp. Alopecia was assessed according to Common Terminology Criter...
Source
#1Alessio BruniH-Index: 15
#2Alessandro StefaniH-Index: 18
Last. Vieri ScottiH-Index: 19
view all 15 authors...
Background Thymoma is a rare mediastinal neoplasia. Surgery is the backbone of the treatment, but the role of postoperative radiotherapy (PORT) remains controversial. We aimed to obtain data on survival and safety in patients treated with PORT in three different Italian institutions. Methods We retrospectively analyzed 183 consecutive patients who underwent surgery from 1981 to 2015. According to the Masaoka-Koga staging system, 39.3%, 32.7%, 18.6% and 9.8% patients were in stage I, II, III and ...
Source
#1Vieri ScottiH-Index: 19
#2Marco PernaH-Index: 5
Last. Lorenzo LiviH-Index: 28
view all 10 authors...
Choroidal localization from non-small cell lung cancer is rare and when it occurs may cause visual alterations. Targeted therapy against actionable gene mutations represents the standard of care in advanced non-small cell lung cancer. We report the case of a 53-year-old woman affected by metastatic anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer who received ALK tyrosine kinase inhibitors, from January 2017. The patient had a complete response of choroidal metastasis after...
Source
#1Vieri ScottiH-Index: 19
#2Alessio BruniH-Index: 15
Last. Lorenzo LiviH-Index: 28
view all 8 authors...
Source
#1Alessio BruniH-Index: 15
#1Alessio Bruni (University of Modena and Reggio Emilia)
Last. Vieri ScottiH-Index: 19
view all 26 authors...
: Concurrent chemotherapy and radiotherapy (cCRT) is considered the standard treatment of locally advanced non-small cell lung cancer (LA-NSCLC). Unfortunately, management is still heterogeneous across different specialists. A multidisciplinary approach is needed in this setting due to recent, promising results obtained by consolidative immunotherapy. The aim of this survey is to assess current LA-NSCLC management in Italy. From January to April 2018, a 15-question survey focusing on diagnostic/...
3 CitationsSource
Source