Jaskiran Kaur
Lovely Professional University
PharmacodynamicsDerivative (finance)PharmacokineticsOutbreakDetection limitInternal medicineEndocrinologyBioanalysisPathologyNanomedicineReceptorNanotechnologyVolumetric flow rateIntensive care medicineHigh-performance liquid chromatographyBioavailabilityNanocarriersGlucagon-like peptide 1 receptorChemistryPeroxisome proliferator-activated receptorMaterials scienceAdverse effectLipophilicityIn vitroIn vivoCmaxOrnamentsWarfarinGlucagon-like peptide-1MycetomaAntagonistCombination therapyType 2 diabetesLopinavirTBARSFisetinInsulin resistanceChloroquineMetabolite4-HydroxycoumarinLungDiabetic foot ulcerEpilepsyAnticoagulantIdiopathic pulmonary fibrosisPioglitazoneRotenoneGlucagonHemostasisIncretinAgonistHydroxychloroquineDiseaseMedicinal plantsInsulinBronchiectasisMental statePharmaceutical industryDrug deliveryPancreatic isletsDrugAspergillomaOseltamivirLung abscessBronchoconstrictionTuberculosisQuercetinSarcoidosisCoumarinDermatological diseasesType 2 Diabetes MellitusSynthetic drugsAge groupsClinical studyFuture studiesTreatment strategySelf nanoemulsifyingIn patientTarget sitePolymeric micellesResearch areasRelevant informationCharacterization methodsMolecular targetingTreatment durationPharmacology toxicologyHigh surface areaLack of efficacyDrug releaseMuscarinic acetylcholine receptorChromatographyPhase (matter)Linear regressionAntimicrobialPharmacotherapyObesityClinical trialDiabetes mellitusTraditional medicinePotencyNuclear receptorAmphiphileADMEPolyphenolMedicinePPAR agonistProtein precipitationArea under the curvePandemicPharmacology
15Publications
3H-index
25Citations
Publications 15
Newest
#1Jaskiran Kaur (LPU: Lovely Professional University)H-Index: 3
#2Vijay Mishra (LPU: Lovely Professional University)H-Index: 22
Last. K. Gowthamarajan (Jagadguru Sri Shivarathreeswara University)H-Index: 17
view all 12 authors...
Abstract Amphiphilic block copolymers are widely utilized in the design of formulations owing to their unique physicochemical properties, flexible structures and functional chemistry. Amphiphilic polymeric micelles (APMs) formed from such copolymers have gained attention of the drug delivery scientists in past few decades for enhancing the bioavailability of lipophilic drugs, molecular targeting, sustained release, stimuli-responsive properties, enhanced therapeutic efficacy and reducing drug as...
1 CitationsSource
#1Ankit Awasthi (LPU: Lovely Professional University)H-Index: 7
#2Sachin Kumar Singh (LPU: Lovely Professional University)H-Index: 19
Last. Ankit Kumar Yadav (LPU: Lovely Professional University)H-Index: 7
view all 14 authors...
Background Diabetic foot ulcer (DFU) is one of the leading complications of type-2 diabetes mellitus. It isassociated with neuropathy and peripheral arterial disease of the lower limb in patients with diabetes. Basically, there are four stages of wound healing namely hemostasis phase, inflammatory phase, proliferative phase and maturation phase. In case of DFU, all these stages are disturbed which lead to delay in healing and consequently to lower limb amputation. Traditionally the dosage forms ...
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#1Jaskiran Kaur (LPU: Lovely Professional University)H-Index: 3
Last. Navneet Khurana (LPU: Lovely Professional University)H-Index: 7
view all 11 authors...
Abstract Ethnopharmacological relevance Epilepsy is one of the most commonly occurring non-communicable neurological disorder that affects people of all age groups. Around 50 million people globally are epileptic, with 80% cases in developing countries due to lack of access to treatments determined by high cost and poor availability or it can be defined by the fraction of active epileptic patients who are not appropriately being treated. The availability of antiepileptic drugs and their adjuvant...
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#1Arya Kadukkattil Ramanunny (LPU: Lovely Professional University)H-Index: 3
#2Sheetu Wadhwa (LPU: Lovely Professional University)H-Index: 13
Last. Narendra Kumar Pandey (LPU: Lovely Professional University)H-Index: 9
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Abstract Skin diseases are the fourth leading non-fatal skin conditions that act as a burden and affect the world economy globally. This condition affects the quality of a patient's life and has a pronounced impact on both their physical and mental state. Treatment of these skin conditions with conventional approaches shows a lack of efficacy, long treatment duration, recurrence of conditions, systemic side effects, etc., due to improper drug delivery. However, these pitfalls can be overcome wit...
3 CitationsSource
Intake of the high level of sugar may cause diabetes which is a metabolic disorder. It is characterized by hyperglycemia, glycosuria, hyperlipidemia, negative nitrogen balance, and ketonemia. Types of diabetes are type 1, is dependent on insulin. The pancreatic islets beta cells are destroyed where most of the cases are autoimmune (Type IA) antibodies that destroy beta cells are detectable in blood, but some are idiopathic also (Type IB). Type 2, is the type of diabetes that is independent of in...
Source
#1Ankit Awasthi (LPU: Lovely Professional University)H-Index: 7
#2Sukriti Vishwas (LPU: Lovely Professional University)H-Index: 2
Last. Ankit Kumar (LPU: Lovely Professional University)H-Index: 2
view all 17 authors...
Abstract Outbreak of Coronavirus disease 2019 (COVID-19) started in mid of December 2019 and spread very rapidly across the globe within a month of its outbreak. Researchers all across the globe started working to find out its possible treatments. However, most of initiatives taken were based on various hypotheses and till date no successful treatments have been achieved. Some strategies adopted by China where existing antiviral therapy was initially used to treat COVID-19 have not given very su...
4 CitationsSource
#1Rajan Kumar (LPU: Lovely Professional University)H-Index: 5
#2Rakesh Kumar (LPU: Lovely Professional University)H-Index: 4
Last. Leander Corrie (LPU: Lovely Professional University)H-Index: 5
view all 13 authors...
Abstract Fisetin (FS) was reported to have various pharmacological activities. But due to its lower aqueous solubility and oral bioavailability, it is not in much use. As solubility and bioavailability plays and important role in the pharmacological activity, in this research work we tried to improve the oral bioavailability of fisetin. In this research work, we developed self-nanoemulsifying drug delivery system (SNEDDS) of fisetin. Developed SNEDDS were subjected for pharmacokinetic and pharma...
6 CitationsSource
#1Paranjeet Kaur (LPU: Lovely Professional University)H-Index: 4
#2Zahid Rafiq BhatH-Index: 2
Last. Gopal L. Khatik (LPU: Lovely Professional University)H-Index: 13
view all 10 authors...
Abstract Diabetes is a ubiquitously a metabolic disorder and life-threatening disease. Peroxisome proliferator-activated receptors (PPARs) belong to the class of nuclear receptors which acts as transcription factors to regulate lipid and glucose metabolism. PPAR alpha/gamma dual agonists tend to corroborate the functions of both thiazolidinediones and fibrates and they hold substantial promise for ameliorating the type 2 diabetic treatments and providing potential therapeutic diabetic interventi...
3 CitationsSource
#1Rajan Kumar (LPU: Lovely Professional University)H-Index: 5
#2Rakesh Kumar (LPU: Lovely Professional University)H-Index: 4
Last. Neha Sharma (LPU: Lovely Professional University)H-Index: 7
view all 12 authors...
Fisetin (FS) is a polyphenolic phytoconstituent reported to have various pharmacological activities such as antioxidant, antiparkinsonian, and antidepressant. An analytical method was developed and...
Source
#1Rajan Kumar (LPU: Lovely Professional University)H-Index: 5
#2Rakesh Kumar (LPU: Lovely Professional University)H-Index: 4
Last. Leander Corrie (LPU: Lovely Professional University)H-Index: 5
view all 11 authors...
Abstract Fisetin is an important phyto-flavonoid that possesses very good anti-oxidant, anti-Parkinson's and anti-cancer activities. A bioanalytical method was developed and validated for the estimation of fisetin in the rat's plasma using reverse phase ultra-fast liquid chromatography combined with a C-18 reverse phase column. Quercetin was used as an internal standard. The mobile phase was composed of acetonitrile and orthophosphoric acid (0.2% v/v) in the ratio of 30:70 v/v. Flow rate was set...
2 CitationsSource