Andrea Ferrero
Mayo Clinic
Imaging phantomOpticsPhysicsRadiologyPET-CTBiomedical engineeringIterative reconstructionArtificial intelligenceTomographyProjection (set theory)Materials scienceImage resolutionPositron emission tomographyScannerNuclear medicinePhoton counting detectorComputer visionMathematicsComputer scienceComputed tomographyResolution (electron density)MedicineFragilityDetector
41Publications
8H-index
215Citations
Publications 39
Newest
#1Felipe Godinez (UC Davis: University of California, Davis)H-Index: 4
#2Buddika Sumanasena (UC Davis: University of California, Davis)H-Index: 4
Last. Ramsey D. Badawi (UC Davis: University of California, Davis)H-Index: 29
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#1Buddika Sumanasena (UC Davis: University of California, Davis)H-Index: 4
#2Felipe GodinezH-Index: 4
Last. Ramsey D. BadawiH-Index: 29
view all 8 authors...
3 Citations
#1Li Yang (UC Davis: University of California, Davis)H-Index: 4
#2Jian Zhou (UC Davis: University of California, Davis)H-Index: 12
Last. Jinyi Qi (UC Davis: University of California, Davis)H-Index: 52
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Detecting cancerous lesions is a major clinical application in emission tomography. In previous work, we have studied penalized maximum-likelihood (PML) image reconstruction for the detection task and proposed a method to design a shift-invariant quadratic penalty function to maximize detectability of a lesion at a known location in a two dimensional image. Here we extend the regularization design to maximize detectability of lesions at unknown locations in fully 3D PET. We used a multiview chan...
22 CitationsSource
Last. Ramsey D. BadawiH-Index: 29
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#1Andrea Ferrero (UC Davis: University of California, Davis)H-Index: 8
#2Alexander D. Borowsky (UC Davis: University of California, Davis)H-Index: 57
Last. Ramsey D. Badawi (UC Davis: University of California, Davis)H-Index: 29
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2250 Objectives To improve the correlation between in-vivo 3D images of the breast and pathology findings after mastectomy. Methods A high resolution breast PET/CT scanner has been built at our institution and is being used in several clinical trials, including the assessment of the potential of dedicated breast PET for the monitoring of tumor response to treatment. Pathology is the gold standard to assess patient response to treatment. Currently spatial correlation between pathology and radiogr...
#1Spencer L. Bowen (Harvard University)H-Index: 11
#2Andrea Ferrero (UC Davis: University of California, Davis)H-Index: 8
Last. Ramsey D. Badawi (UC Davis: University of California, Davis)H-Index: 29
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Purpose: Dedicated breast PET/CT is expected to have utility in local staging, surgical planning, monitoring of therapy response, and detection of residual disease for breast cancer. Quantitative metrics will be integral to several such applications. The authors present a validation of fully 3D data correction schemes for a custom built dedicated breast PET/CT (DbPET/CT) scanner via 18F-FDG phantom scans. Methods: A component-based normalization was implemented, live-time was estimated with a mu...
10 CitationsSource
#2Andrea FerreroH-Index: 8
Last. Ramsey D. BadawiH-Index: 29
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#1Andrea Ferrero (UC Davis: University of California, Davis)H-Index: 8
#2Jonathan K Poon (UC Davis: University of California, Davis)H-Index: 6
Last. Ramsey D. Badawi (UC Davis: University of California, Davis)H-Index: 29
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Scatter fraction (SF ) for PET scanners is typically estimated by making a single measurement using a solid cylindrical phantom with a line source radially offset from the center. The radial displacement of the line source is expected to give a value for scatter fraction that is representative of a typical PET scan for a scanner. A range of phantom sizes suitable for small animal and whole-body PET scanners is investigated. For whole-body imaging, we simulate phantom diameters ranging from 15 to...
8 CitationsSource
#1Andrea Ferrero (UC Davis: University of California, Davis)H-Index: 8
#2Qiyu Peng (LBNL: Lawrence Berkeley National Laboratory)H-Index: 9
Last. Ramsey D. Badawi (UC Davis: University of California, Davis)H-Index: 29
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The combined effort of several laboratories at our institution resulted in the building of the first dedicated, breast PET/CT prototype. Ongoing clinical trials for breast cancer diagnosis and assessment of response to treatment underlined the need of a second generation prototype with improved sensitivity and spatial resolution. The goals of the new prototype are to reduce scan time and partial volume effects on quantitative measurements of small lesions. Several designs have been proposed by o...
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