Andrea Ferrero
Mayo Clinic
Imaging phantomOpticsPhysicsRadiologyPET-CTBiomedical engineeringIterative reconstructionArtificial intelligenceTomographyProjection (set theory)Materials scienceImage resolutionPositron emission tomographyScannerNuclear medicinePhoton counting detectorComputer visionMathematicsComputer scienceComputed tomographyResolution (electron density)MedicineFragilityDetector
41Publications
8H-index
215Citations
Publications 39
Newest
#1Andrea Ferrero (Mayo Clinic)H-Index: 8
#2J. Montoya (Mayo Clinic)H-Index: 4
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
view all 8 authors...
Rationale and Objectives Previous studies have demonstrated a qualitative relationship between stone fragility and internal stone morphology. The goal of this study was to quantify morphologic features from dual-energy computed tomography (CT) images and assess their relationship to stone fragility. Materials and Methods Thirty-three calcified urinary stones were scanned with micro-CT. Next, they were placed within torso-shaped water phantoms and scanned with the dual-energy CT stone composition...
7 CitationsSource
#1J. Montoya (Mayo Clinic)H-Index: 4
#2Andrea Ferrero (Mayo Clinic)H-Index: 8
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
view all 5 authors...
Purpose: To investigate the noise and spatial resolution properties of virtual non-contrast (VNC) dual-energy CT images compared to true non-contrast (TNC) images across multiple patient sizes and CT systems. Methods: Torso-shaped water phantoms with lateral widths of 25, 30, 35, 40 and 45 cm and a high resolution bar pattern phantom (Catphan CTP528) were scanned using 2nd and 3rd generation dual-source CT systems (Scanner A: Somatom Definition Flash, Scanner B: Somatom Force, Siemens Healthcare...
2 CitationsSource
#1Christopher P. Favazza (Mayo Clinic)H-Index: 24
#2Andrea Ferrero (Mayo Clinic)H-Index: 8
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
view all 8 authors...
Purpose: To evaluate CT low-contrast detectability at different dose levels in images reconstructed using filtered backprojection (FBP) and iterative reconstruction (IR). Methods: A validated channelized Hotelling observer (CHO) model was used to detect low contrast objects in images of a helical CT phantom (Model 061, CIRS) using an Aquilion Prime 160 scanner (Toshiba Medical Systems). Twenty-one different objects of 7 diameters (2.4, 3.2, 4.6, 6.3, 9.5, and 10 mm) and 3 contrast levels (∼10, 1...
Source
#1Andrea Ferrero (Mayo Clinic)H-Index: 8
#2Baiyu Chen (Mayo Clinic)H-Index: 13
Last. Cynthia H. McCollough (Mayo Clinic)H-Index: 76
view all 6 authors...
Purpose: In order to investigate novel methods to more accurately estimate the mineral composition of kidney stones using dual energy CT, it is desirable to be able to combine digital stones of known composition with actual phantom and patient scan data. In this work, we developed and validated a method to insert digital kidney stones into projection data acquired on a dual-source, dual-energy CT system. Methods: Attenuation properties of stones of different mineral composition were computed usi...
Source
#1Abhijit J. Chaudhari (UC Davis: University of California, Davis)H-Index: 18
#2Andrea Ferrero (UC Davis: University of California, Davis)H-Index: 8
Last. Ramsey D. Badawi (UC Davis: University of California, Davis)H-Index: 29
view all 10 authors...
Objective:Rheumatoid arthritis (RA) and psoriatic arthritis (PsA) commonly affect the small joints of the wrist and hand. We evaluated the performance of a new, high-resolution extremity positron emission tomography (PET)/CT scanner for characterizing and quantifying pathologies associated with the two arthritides in the wrist and hand joints.Methods:Patients with RA or PsA underwent fluorine-18 fludeoxyglucose (18F-FDG) PET/CT wrist and hand imaging, respectively, on the high-resolution scanner...
24 CitationsSource
#1Buddika Sumanasena (UC Davis: University of California, Davis)H-Index: 4
#2Qiyu PengH-Index: 9
Last. Ramsey D. Badawi (UC Davis: University of California, Davis)H-Index: 29
view all 7 authors...
POSITRON emission tomography (PET) is used in assessing therapy response, staging, and restaging of breast cancer [1]. However, whole-body PET scanners are not ideally suited to breast imaging due to low geometric sensitivity, low spatial resolution and signal loss due to attenuation in the body. Several groups are working on dedicated breast imaging systems to overcome such limitations[2][3]. Due to the typically smaller field of view (FOV), detectors capable of measuring depth of interaction (...
Source
#1Andrea Ferrero (UC Davis: University of California, Davis)H-Index: 8
#2Qiyu Peng (LBNL: Lawrence Berkeley National Laboratory)H-Index: 9
Last. Ramsey D. Badawi (UC Davis: University of California, Davis)H-Index: 29
view all 6 authors...
The combined effort of several laboratories at our institution resulted in the building of the first high-resolution PET/CT prototype dedicated to imaging the extremities of the body. Ongoing clinical trials for breast-cancer diagnosis and assessment of the response to treatment underlined the need for a second-generation prototype with improved electronics and spatial resolution. A preliminary version has been assembled and fully characterized. In this work, we present further improvements in d...
8 CitationsSource
#1Li Yang (UC Davis: University of California, Davis)H-Index: 4
#2Andrea Ferrero (UC Davis: University of California, Davis)H-Index: 8
Last. Jinyi Qi (UC Davis: University of California, Davis)H-Index: 52
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Detecting cancerous lesions is a major clinical application in emission tomography. Previously, we developed a method to design a shift-variant quadratic penalty function in penalized maximum-likelihood (PML) image reconstruction to improve the lesion detectability. We used a multiview channelized Hotelling observer (mvCHO) to assess the lesion detectability in three-dimensional images and validated the penalty design using computer simulations. In this study, we evaluate the benefit of the prop...
4 CitationsSource
#1Jonathan Santos (UC Davis: University of California, Davis)H-Index: 2
#2Abhijit J. Chaudhari (UC Davis: University of California, Davis)H-Index: 18
Last. Ramsey D. Badawi (UC Davis: University of California, Davis)H-Index: 29
view all 7 authors...
Abstract Rationale and objectives Dedicated breast CT and PET/CT scanners provide detailed 3D anatomical and functional imaging data sets and are currently being investigated for applications in breast cancer management such as diagnosis, monitoring response to therapy and radiation therapy planning. Our objective was to evaluate the performance of the diffeomorphic demons (DD) non-rigid image registration method to spatially align 3D serial (pre- and post-contrast) dedicated breast computed tom...
8 CitationsSource
#1Andrea FerreroH-Index: 8
#2Qiyu PengH-Index: 9
Last. Ramsey D. BadawiH-Index: 29
view all 10 authors...