Hai-Tao Chang
Peking University
PharmacognosyCarbon-13 NMRChemical structureOrganic chemistryChemistryGlycosideTwo-dimensional nuclear magnetic resonance spectroscopyTerpenoidLactoneAlkaloidRanunculaceaeHerbFolk medicineSemiaquilegia adoxoidesLithospermosideChemical constituentsChromatographyTraditional medicineNuclear magnetic resonance spectroscopyStereochemistry
10Publications
7H-index
176Citations
Publications 9
Newest
#1Jing Wen (PKU: Peking University)H-Index: 6
#2Haiming ShiH-Index: 24
Last. Peng-Fei TuH-Index: 54
view all 8 authors...
A new dimeric guaianolide (8) and a new glaucolide (3), a seco-guaiaretic acid (4), two guaianolides (6 and 7), and five known sesquiterpene lactones (1, 2, 5, 9, and 10) were isolated from the aerial part of Artemisia anomala. Their structures were determined on the basis of chemical and spectroscopic analysis. In addition, their cytotoxic activities against five human cancer cell lines and anti-COX-2 effects in vitro were evaluated.
42 CitationsSource
#1Hai-Tao Chang (PKU: Peking University)H-Index: 7
#2Yoshihito Okada (Meiji Pharmaceutical University)H-Index: 10
Last. Peng-Fei Tu (PKU: Peking University)H-Index: 54
view all 5 authors...
Two new coumarin glycosides, praerosides VI (1) and VII (2), were isolated from the roots of Peucedanum praeruptorum Dunn. Their structures were elucidated by chemical reaction and NMR spectroscopic methods.
13 CitationsSource
#1Hai-Tao Chang (PKU: Peking University)H-Index: 7
#2Feng NiuH-Index: 5
Last. Peng-Fei TuH-Index: 54
view all 5 authors...
Objective: To study the chemical constituents from the whole plants of Polygala telephioides.Method: Compounds were isolated by repeated silica gel and Sephadex LH-20 column chromatography,and their structures were determined by spectral analysis and physicochemical properties.Result: Six xanthones were isolated from P.telephioides,and their structures were identified as 1,3,7-trihydroxyxanthone(1),1,7-dihydroxy-3-methoxyxanthone(2),1,3-dihydroxyxanthone(3),1,7-dihydroxyxanthone(4),1-methoxy-2,3...
5 Citations
#1Hai-Tao Chang (PKU: Peking University)H-Index: 7
#2Yoshihito Okada (Meiji Pharmaceutical University)H-Index: 10
Last. Peng-Fei Tu (PKU: Peking University)H-Index: 54
view all 4 authors...
Two novel angular-type furanocoumarin glycosides, peucedanoside A (1) and peucedanoside B (2), along with a known compound apterin (3), were isolated from the roots of Peucedanum praeruptorum Dunn. Their chemical structures were determined by MS, NMR spectroscopy and chemical analysis. Complete assignments of the 1H and 13C NMR spectroscopic data were achieved by 1D and 2D NMR experiments including DEPT, HSQC, HMBC and ROESY. Copyright © 2007 John Wiley & Sons, Ltd.
15 CitationsSource
#1Feng Niu (PKU: Peking University)H-Index: 5
#2Zheng Cui (SPU: Shenyang Pharmaceutical University)H-Index: 7
Last. Peng-Fei Tu (PKU: Peking University)H-Index: 54
view all 6 authors...
In present literature search, some cyano-containing compounds, which are very rare in plants, from the traditional anticancer herb Tiankuizi were reported. To find more cyano-containing compounds in the important plant Semiaquilegia adoxoides (DC) Makino (Chinese name Tiankuizi), the isolation of the chemical constituents was investigated for advancing the research. Two new compounds, a new alkaloid, 1,2,3,4-tetrahydro-6-hydroxy-1- [(3,4-dihydroxyphenyl)methyl]-7-methoxy-2,2-dimethyl-isoquinolin...
9 CitationsSource
#1Feng Niu (PKU: Peking University)H-Index: 5
#2Zheng Cui (SPU: Shenyang Pharmaceutical University)H-Index: 7
Last. Peng-Fei Tu (PKU: Peking University)H-Index: 54
view all 7 authors...
Semiaquilegoside A (1), a new diterpenoid, was isolated from the roots of Semiaquilegia adoxoides. Its chemical structure was established as 3β, 11- dihydroxy-12-O-β-D-glucopyranosyl-8,11,13-abietatrien-6-one through spectroscopic techniques and chemical analysis. Copyright © 2006 John Wiley & Sons, Ltd.
5 CitationsSource
#1Feng Niu (PKU: Peking University)H-Index: 5
#2Hai-Tao Chang (PKU: Peking University)H-Index: 7
Last. Peng-Fei Tu (PKU: Peking University)H-Index: 54
view all 7 authors...
Two new ent-kaurane-type diterpenoids, E-semiaquilegin (1) and Z-semiaquilegin (2), together with eight known compounds (3–10) were isolated from the dried roots of Semiaquilegia adoxoides (DC.) Makino. The structures of compounds 1 and 2 were elucidated mainly by 2D NMR techniques including 1H–1H COSY, HSQC, HMBC, NOESY as 16α-hydroxy-ent-kaurane-17,20-di-(3,4-dihydroxy-E-cinnamoyl) ester and its (Z)-isomer.
8 CitationsSource
#1Li Tang (PKU: Peking University)H-Index: 3
#2Yong JiangH-Index: 31
Last. Rui-Qing WangH-Index: 1
view all 7 authors...
Nine new triterpene saponins, ilekudinosides K-S (1-9), and eight known triterpene saponins were isolated from the 70% ethanol extract of the leaves of Ilex kudingcha. The new saponins were characterized as 3-O-a-L-rhamnopyranosyl(1→2)-β-D-glucopyranosyl-a-kudinlactone (1), 3-O-β-D-glucopyranosyl(1→3)-a-L-arabinopyranosyl-β-kudinlactone (2), 3-O-α-L-rhamnopyranosyl(1→2)-a-L-arabinopyranosyl-y-kudin-lactone (3), 3-O-β-D-glucopyranosyl(1→2)-β-D-glucopyranosyl-a-kudinlactone (4), 3-O-β-D-glucopyran...
46 CitationsSource
#1Hai-Tao Chang (PKU: Peking University)H-Index: 7
#2Wei-liang KongH-Index: 1
Last. Peng-fei TuH-Index: 1
view all 3 authors...
The progress in the research of the chemical components and pharmacological activities of Lysimachia was reviewed. Lysimachia mainly contain flavonoids, saponins and phenolic acids, and some of the plants have been used in the treatment of fever, ulcers, diarrhea and as analgesic or anti inflammatory agents. The plants of genus Lysimachia are widespread in China, so it is a singificants work to study their chemical ingredients and pharmacological activities.
3 Citations