E. M. Wesselink
Utrecht University
Support vector machineInternal medicineNeutrophil extracellular trapsPerfusionCerebral perfusion pressureOdds ratioCardiologyReceptorIntensive care medicineCohort studyImmunologyData pointSide effectAnnotationIntensive care unitMean arterial pressureGeneral anaesthesiaLasso (statistics)Cardiac surgeryBronchiolitisAnesthesiologyDeliriumAcute kidney injuryArtifact (software development)ConfusionCINAHLPostoperative deliriumImmune regulationViral immunologyComputer scienceAnesthesiaArtificial neural networkStrokeMedicineConfoundingIdentification (information)Blood pressureBiology
Publications 8
#1E. M. Wesselink (UU: Utrecht University)H-Index: 3
#2Masieh Abawi (UU: Utrecht University)H-Index: 8
Last. Charlotte S. van Dongen (UU: Utrecht University)H-Index: 3
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BACKGROUND Postoperative delirium (POD) is a frequently observed complication after transcatheter aortic valve replacement (TAVR). The effects of intraoperative hypotension (IOH) on POD occurrence are currently unclear. METHODS A retrospective observational cohort study of patients who underwent TAVR was conducted. We predefined IOH as area under the threshold (AUT) of five mean arterial blood pressures (MBP), varying from <100 to <60 mmHg. The AUT consisted of the combination of duration and de...
#1Shokoufeh CheheiliSobbi (Radboud University Nijmegen)
#2Annemieke M. Peters van Ton (Radboud University Nijmegen)H-Index: 2
Last. Mark van den Boogaard (Radboud University Nijmegen)H-Index: 23
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BACKGROUND Delirium occurs frequently following cardiothoracic surgery, and infectious disease is an important risk factor for delirium. Surgery and cardiopulmonary bypass induce suppression of the immune response known as immunoparalysis. We aimed to investigate whether delirious patients had more pronounced immunoparalysis following cardiothoracic surgery than patients without delirium, to explain this delirium-infection association. METHODS A prospective matched case-control study was perform...
#1Wietze Pasma (UU: Utrecht University)H-Index: 9
#2E. M. Wesselink (UU: Utrecht University)H-Index: 3
Last. Wilton A. van Klei (UU: Utrecht University)H-Index: 19
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Physiologic data from anesthesia monitors are automatically captured. Yet erroneous data are stored in the process as well. While this is not interfering with clinical care, research can be affected. Researchers should find ways to remove artifacts. The aim of the present study was to compare different artifact annotation strategies, and to assess if a machine learning algorithm is able to accept or reject individual data points. Non-cardiac procedures requiring invasive blood pressure monitorin...
Abstract Background Intraoperative hypotension is a common side effect of general anaesthesia and might lead to inadequate organ perfusion. It is unclear to what extent hypotension during noncardiac surgery is associated with unfavourable outcomes. Methods We conducted a systematic search in PubMed, Embase, Web of Science, and CINAHL, and classified the quality of retrieved articles according to predefined adapted STROBE and CONSORT criteria. Reported strengths of associations from high-quality ...
#1Ruben J. Geerdink (UU: Utrecht University)H-Index: 4
#2Marije P. Hennus (UU: Utrecht University)H-Index: 11
Last. Linde Meyaard (UU: Utrecht University)H-Index: 35
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#1E. M. Wesselink (UU: Utrecht University)H-Index: 3
#2Teus H. Kappen (UU: Utrecht University)H-Index: 21
Last. Arjen J. C. Slooter (UU: Utrecht University)H-Index: 2
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BACKGROUND: Delirium is a common complication after cardiac surgery and may be as a result of inadequate cerebral perfusion. We studied delirium after cardiac surgery in relation to intraoperative hypotension (IOH). METHODS: This observational single-centre, cohort study was nested in a randomized trial, on a single intraoperative dose of dexamethasone vs placebo during cardiac surgery. During the first four postoperative days, patients were screened for delirium based on the Confusion Assessmen...
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