Yannick Hoyos-Mallecot
Autonomous University of Barcelona
GeneSubclinical infectionOutbreakGeneXpert MTB/RIFInternal medicineGenotypePublic healthMucocutaneous zoneInsertion sequenceVirologyMass spectrometryInfection controlPenicillinImmunologyPlasmidWhole genome sequencingGentamicinPathogenLeishmaniasisMen who have sex with menSyphilisChlamydia trachomatisPseudomonas aeruginosaAsymptomaticSpectinomycinCefiximeErtapenemCiprofloxacinTest (assessment)Visceral leishmaniasisFosfomycinEnterobacteriaceaeNeisseria gonorrhoeaeBlood cultureImipenemMycoplasma genitaliumTypingPseudomonasConjugative plasmidPopulationCarbapenemase-Producing EnterobacteriaceaeGenus: LeishmaniaLeclercia adecarboxylataEarly detectionHigh morbidityImmune statusClinical microbiologySample collectionC contentRapid detectionPredictive valueClinical evaluationMacrolide resistanceCarriage23S ribosomal RNAVeterinary medicineSerologyAntimicrobialFamily medicineGeneticsEscherichia coliHygienePopulation studyCephalosporinMedicineMatrix-assisted laser desorption/ionizationSanger sequencingMultilocus sequence typingBiologyMicrobiologyVector (molecular biology)Antibiotic resistance
Publications 11
#2Jorge Nestor Garcia (Hebron University)
#3Elena Sulleiro (Hebron University)H-Index: 18
Last. Mateu EspasaH-Index: 27
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BACKGROUND STIs are a major public health concern. Screening programmes for asymptomatic users are key components of STI control. Traditional limitations of screening programmes include low population coverage and delays in treatments, thus reducing the expected impact on STI control. In our centre, the normal time from test to results was 4 days, and 7 days until treatment was established.To reduce time to treatment and to increase population coverage, we developed 'Drassanes Expres', a testing...
#1Paula Salmerón (Autonomous University of Barcelona)H-Index: 2
#2Albert Moreno-Mingorance (Autonomous University of Barcelona)H-Index: 3
Last. Juan José González-López (Autonomous University of Barcelona)H-Index: 39
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BACKGROUND Neisseria gonorrhoeae (NG) isolates with high-level azithromycin resistance (HL-AziR) have emerged worldwide in recent decades, threatening the sustainability of current dual-antimicrobial therapy. OBJECTIVES This study aimed to characterize the first 16 NG isolates with HL-AziR in Barcelona between 2016 and 2018. METHODS WGS was used to identify the mechanisms of antimicrobial resistance, to establish the MLST ST, NG multiantigen sequence typing (NG-MAST) ST and NG sequence typing fo...
3 CitationsSource
#1Paula SalmerónH-Index: 2
#2Belén ViñadoH-Index: 11
Last. Judit Serra-Pladevall (Autonomous University of Barcelona)H-Index: 8
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Introduction Increasing rates of antimicrobial resistance in Neisseria gonorrhoeae cause problems for treating gonorrhoea. Aim This observational study aimed to describe isolates from all patients found infected with N. gonorrhoeae, in Barcelona, Spain, between 2013 and 2017, and with available antimicrobial susceptibility data. Methods Minimum inhibitory concentrations (MICs) of penicillin (PEN), cefixime (CFM), ceftriaxone (CRO), azithromycin (AZM), ciprofloxacin (CIP), spectinomycin (SPT), fo...
3 CitationsSource
#1Miguel Fernández-Huerta (Autonomous University of Barcelona)H-Index: 5
#2Paula Salmerón (Autonomous University of Barcelona)H-Index: 2
Last. Judit Serra-Pladevall (Autonomous University of Barcelona)H-Index: 8
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Abstract Antibiotic resistance in Mycoplasma genitalium (MG) is rising globally, especially to macrolides. In response to this challenge, assays reporting both the detection of MG and macrolide resistance-mediating mutations (MRMM) allow therapy to be tailored to the individual. The study evaluated the performance of the ResistancePlus® MG FleXible assay for the detection of MG and MRMM. Overall, the test performed well for the detection of MG compared to the Allplex™ STI Essential assay, used a...
1 CitationsSource
#1Yannick Hoyos-Mallecot (Université Paris-Saclay)H-Index: 6
#2Thierry NaasH-Index: 81
Last. Laurent DortetH-Index: 38
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ABSTRACT OXA-244 is a single-point-mutant derivative of OXA-48 displaying reduced carbapenemase activity. Here, we report the microbiological features of seven OXA-244-producing Escherichia coli isolates. Only one isolate grew on ChromID Carba Smart medium (bioMerieux), but six of the seven isolates grew on ChromID extended-spectrum-β-lactamase (ESBL) medium (bioMerieux), as they coproduced an ESBL and/or a plasmid-encoded cephalosporinase. The production of a carbapenemase was detected in 57.1%...
33 CitationsSource
Abstract We describe the case of NDM-1-producing Leclercia adecarboxylata recovered from the clinical sample of a patient hospitalized for a trauma-related injury to his foot. The isolate was resistant to all beta-lactams, quinolones, trimetroprim-sulfametoxazol, gentamicin and tobramicyn. The bla NDM-1 gene was located in a conjugative plasmid that also contained the bla SHV-12 gene and was preceded by a disrupted insertion sequence of IS Aba125. The plasmid belongs to the incompatibility group...
16 CitationsSource
#1Yannick Hoyos-Mallecot (Université Paris-Saclay)H-Index: 6
#2Souad OuzaniH-Index: 1
Last. Thierry NaasH-Index: 81
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Abstract Early detection of patients colonised with carbapenemase-producing Enterobacteriaceae (CPE) is crucial for implementing proper infection control measures. Here we evaluated the biological performance of the Xpert ® Carba-R v2 (Cepheid) in the daily workflow of a hygiene unit in a country with a low CPE prevalence. Patients repatriated from countries known for high CPE prevalence or contact patients of a known CPE carrier were targeted as being ‘high-risk patients’ for CPE carriage. Betw...
27 CitationsSource
#1Yannick Hoyos-Mallecot (Université Paris-Saclay)H-Index: 6
Last. Thierry NaasH-Index: 81
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ABSTRACT Here, we provide the first draft genome sequence of NDM-1-producing Leclercia adecarboxylata, a human-opportunistic pathogen. The draft genome sequence consists of a total length of 5.13 Mbp, with an average G+C content of 55.2%.
5 CitationsSource
#1Yannick Hoyos-Mallecot (UGR: University of Granada)H-Index: 6
#2Cristina RiazzoH-Index: 7
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Abstract MALDI-TOF MS has been evaluated to detect carbapenemases activity and pathogen identification directly from positive blood cultures. 21 non-carbapenemase producers and 19 carbapenemase producers Enterobacteriaceae and Pseudomonas aeruginosa strains were included in the study. This technique is simple and detects carbapenemases in 4.5 h with high sensitivity and specificity.
28 CitationsSource
Leishmaniasis is a clinically heterogeneous syndrome caused by intracellular protozoan parasites of the genus Leishmania. The clinical spectrum of leishmaniasis encompasses subclinical ( not apparent), localized (skin lesion), and disseminated (cutaneous, mucocutaneous, and visceral) infection. This spectrum of manifestations depends on the immune status of the host, on the parasite, and on immunoinflammatory responses. Visceral leishmaniasis causes high morbidity and mortality in the developing...
94 CitationsSource