Suyue Pan
Southern Medical University
Internal medicinePathologyReceptorImmunologyNeuroprotectionStatus epilepticusCerebral edemaCerebrospinal fluidModified Rankin ScalePathogenesisHippocampusAnesthesiaStrokeNMDA receptorMedicineEncephalitisBiologyNeuroinflammationGastroenterologyPharmacology
Publications 55
#1Yihua He (Southern Medical University)H-Index: 2
#2Yuqin Peng (Southern Medical University)H-Index: 1
Last. Suyue Pan (Southern Medical University)H-Index: 13
view all 7 authors...
Radiation-induced brain injury (RBI) is a common complication of radiotherapy for head and neck tumors while its mechanism is not fully understood. Animal whole-brain radiation (WBR) models are of key importance in experimental radiation research, and an appropriate radiation source is essential. Previous animal WBR models were administered by clinical linear accelerator to induce the pathophysiological changes of RBI. In the current study, we adopted Faxitron MultiRad 225 X-ray irradiation syst...
#1Kewei Liu (Southern Medical University)H-Index: 4
#2Juan Zhu (Southern Medical University)H-Index: 3
Last. Kaibin Huang (Southern Medical University)H-Index: 12
view all 10 authors...
Status epilepticus (SE) is a neurological emergency usually accompanied by acute cerebral edema and long-term cognitive impairment, and is characterized by neurodegeneration and aberrant hyperphosphorylated tau protein (p-tau) aggregation. The glia-lymphatic (glymphatic) system plays a central role in facilitating the clearance of metabolic waste from the brain, but its relationship with cerebral edema and cognitive dysfunction after SE is unclear. We hypothesized that cerebral edema after SE mi...
#1Pingping Song (Southern Medical University)H-Index: 4
#2Yuqing Guan (Southern Medical University)H-Index: 1
Last. Yafang Hu (Southern Medical University)H-Index: 12
view all 17 authors...
Background Deafness-dystonia-optic neuronopathy (DDON) syndrome is a progressive X-linked recessive disorder characterised by deafness, dystonia, ataxia and reduced visual acuity. The causative gene deafness/dystonia protein 1 (DDP1)/translocase of the inner membrane 8A (TIMM8A) encodes a mitochondrial intermembrane space chaperon. The molecular mechanism of DDON remains unclear, and detailed information on animal models has not been reported yet. Methods and results We characterized a family wi...
#1Kaibiao Xu (Southern Medical University)H-Index: 1
#2Dongmei Wang (Southern Medical University)H-Index: 6
Last. Yihua Huang (Southern Medical University)
view all 14 authors...
ABSTRACT null Objective null Autoimmune encephalitis (AE) is a large category disorder urging antibody characterization. The aim was to identify a novel AE related autoantibody targeting an intracellular synaptic protein. null Methods null Suspected AE patients had negative conventional antibodies screening but strong immunolabel signals on rat brain sections with the serum and cerebrospinal fluid (CSF) samples were considered burdening unkown antibody. null Immunoprecipitation from the rat brai...
#1Yu Peng (Southern Medical University)H-Index: 4
#2Yingshan Liu (Southern Medical University)H-Index: 3
Last. Lingling Xu (Southern Medical University)H-Index: 7
view all 11 authors...
Background: There are many methods to diagnose diabetic autonomic neuropathy (DAN); however, often the various methods do not provide consistent results. Even the 2 methods recommended by the American Diabetes Association (ADA) guidelines, Ewing’s test and heart rate variability (HRV), sometimes give conflicting results. The purpose of this study was to evaluate the degree of agreement of the results of the Composite Autonomic Symptom Score 31 (COMPASS-31), skin sympathetic reaction (SSR) test, ...
#1Xuewu Liu (Southern Medical University)H-Index: 1
#2Yongming Wu (Southern Medical University)H-Index: 11
Last. Jiao Liang (Fourth Military Medical University)H-Index: 4
view all 8 authors...
Abstract Cerebral malaria (CM) is the most severe complication caused by Plasmodium falciparum infection. The pathophysiological changes caused by parasite virulence factors and the human immune response to parasites contribute to CM. To date, very few parasite virulence proteins have been found to participate in CM. Here, we employed comparative genomics analysis and identified parasite-infected erythrocyte specific protein 2 (PIESP2) to be a CM-related protein. We conducted further experimenta...
#1Chuqiao Li (Southern Medical University)H-Index: 1
#2Anqi Jiang (Southern Medical University)H-Index: 1
Last. Yu Peng (Southern Medical University)H-Index: 4
view all 10 authors...
INTRODUCTION Turns-amplitude, number of small segments (NSS)-activity, and envelope-activity clouds are three methods of electromyography (EMG) interference pattern analysis. Our objective was to evaluate the sensitivity and specificity of each individual cloud analysis and combined clouds analysis to compare with that of quantitative motor unit potential (QMUP) analysis. METHODS A total of 379 muscles from 100 patients were analyzed by both QMUP and clouds analyses. Calculation of sensitivity a...
#1Xing Li (SCUT: South China University of Technology)H-Index: 1
#2Jiajia Zhu (Southern Medical University)H-Index: 7
Last. Suyue Pan (Southern Medical University)H-Index: 13
view all 6 authors...
#1Xing Chen (Southern Medical University)H-Index: 1
#2Kewei Liu (Southern Medical University)H-Index: 4
Last. Suyue Pan (Southern Medical University)H-Index: 13
view all 5 authors...
This study aimed to evaluate whether the knockout of transient receptor potential melastatin 4 (TRPM4) could reduce cerebral edema and improve neurologic outcome in a mouse model of status epilepticus (SE). Wild-type (WT) (n = 61) and Trpm4-/- mice (n = 61) with behavioral seizures induced by lithium (10 mEq/kg) and pilocarpine (30-40 mg/kg) were terminated 2.5 hours after the onset of SE. After SE, 28 WT-SE and 27 Trpm4-/--SE mice were observed for 28 days and assessed for survival and cognitiv...
#1Cong Zou (Guangzhou Medical University)
#2Shanshan Pei (Southern Medical University)H-Index: 3
Last. Dong Zheng (Guangzhou Medical University)H-Index: 8
view all 10 authors...
Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune neurological disorder. Osteopontin (OPN) is a secreted multifunctional phosphorylated glycoprotein that regulates various autoimmune and inflammatory diseases, but its diagnostic and prognostic values in anti-NMDAR encephalitis patients remain elusive. This retrospective study aimed to determine the levels of OPN and related cytokines in cerebrospinal fluid (CSF) of anti-NMDAR encephalitis patients and to assess their ...
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