Nicole R. Villemarette-Pittman
LSU Health Sciences Center New Orleans
EtiologyDevelopmental psychologyPathologyPsychologyRandomized controlled trialCognitionIctalIntensive care medicinePediatricsPersonalityInjury preventionMedical recordPlaceboMyoclonusStatus epilepticusEpilepsyPhenytoinDiseaseAngerAggressionEpilepsia partialis continuaLorazepamContext (language use)ImpulsivityPanicAggression ScaleImpulsive aggressionElectronic dataCoronavirus disease 2019 (COVID-19)Poison controlAnesthesiaProportional hazards modelStrokeElectroencephalographyAudiologyClinical psychologyMedicinePandemic
26Publications
14H-index
749Citations
Publications 27
Newest
#1David Chachkhiani (LSU Health Sciences Center New Orleans)H-Index: 1
#2Marine Isakadze (LSU Health Sciences Center New Orleans)H-Index: 1
Last. Jesus Lovera (LSU Health Sciences Center New Orleans)H-Index: 18
view all 5 authors...
INTRODUCTION: Altered Mental Status (AMS) is a common neurological complication in patients hospitalized with the diagnosis of COVID-19 (Umapathi et al., 2020; Liotta et al., 2020). Studies show that AMS is associated with death and prolonged hospital stay. In addition to respiratory insufficiency, COVID-19 causes multi-organ failure and multiple metabolic derangements, which can cause AMS, and the multi-system involvement could account for the prolonged hospital stay and increased mortality. In...
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Abstract The COVID-19 pandemic has devastated individuals, families, and institutions throughout the world. Despite the breakneck speed of vaccine development, the human population remains at risk of further devastation. The decision to not become vaccinated, the protracted rollout of available vaccine, vaccine failure, mutational forms of the SARS virus, which may exhibit mounting resistance to our molecular strike at only one form of the viral family, and the rapid ability of the virus(es) to ...
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#1Aditi Vian Varma-Doyle (LSU Health Sciences Center New Orleans)H-Index: 1
#2Nicole R. Villemarette-Pittman (LSU Health Sciences Center New Orleans)H-Index: 14
Last. Brian J Copeland (LSU Health Sciences Center New Orleans)H-Index: 1
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Abstract Magnetic resonance guided focused ultrasound (MRgFUS) thalamotomy targets the ventral intermediate nucleus of the thalamus and has been shown to be safe and effective to treat medication-resistant essential tremors. Improvement in tremor scores, posture and action scores, disability scores and quality of life scores have been reported in patients treated with this procedure. Adverse events are usually transient and non-severe. We present a patient who underwent MRgFUS thalamotomy of the...
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#1David Chachkhiani (LSU Health Sciences Center New Orleans)H-Index: 1
#2Michael Y. Soliman (LSU Health Sciences Center New Orleans)H-Index: 3
Last. Jesus Lovera (LSU Health Sciences Center New Orleans)H-Index: 18
view all 7 authors...
Abstract We reviewed the electronic medical records (EMR) of patients hospitalized during the peak of the pandemic, March 1st through March 31st, to document the type and frequency of neurological problems seen in patients with COVID-19 at presentation to the emergency room. Secondary aims were to determine: 1) the frequency of neurological complaints during the hospital stay; 2) whether the presence of any neurological complaint at presentation or any of the individual types of neurological com...
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#1Rima El-Abassi (LSU: Louisiana State University)H-Index: 7
#2Michael Y. Soliman (LSU: Louisiana State University)H-Index: 3
Last. John D. England (LSU: Louisiana State University)H-Index: 34
view all 4 authors...
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#1David Chachkhiani (LSU Health Sciences Center New Orleans)H-Index: 1
#2Michael Y. Soliman (LSU Health Sciences Center New Orleans)H-Index: 3
Last. Jesus Lovera (LSU Health Sciences Center New Orleans)H-Index: 18
view all 7 authors...
People with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection, COVID-19, can have neurological problems including headache, anosmia, dysgeusia, altered mental status (AMS), ischemic stroke with or without large vessel occlusion, and Guillen-Barre Syndrome. Louisiana was one of the states hit hardest by the pandemic with just over 57,000 laboratory-confirmed cases of COVID-19 by the end of June 2020. We reviewed the electronic medical records (EMR) of patients hospitalized du...
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#1Elliot M. Frohman (University of Texas at Austin)H-Index: 84
#2Nicole R. Villemarette-Pittman (LSU Health Sciences Center New Orleans)H-Index: 14
Last. Teresa C. Frohman (University of Texas at Austin)H-Index: 37
view all 10 authors...
Abstract Here, in Part II of a duology on the characterization and potential treatment for COVID-19, we characterize the application of an innovative treatment regimen for the prevention of the transition from mild to severe COVID-19, as well as detail an intensive immunotherapy intervention hypothesis. We propose as a putative randomized controlled trial that high-dose methotrexate with leucovorin (HDMTX-LR) rescue can abolish ‘PANIC’, thereby ‘left-shifting’ severe COVID-19 patients to the gro...
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#1Elliot M. Frohman (University of Texas at Austin)H-Index: 84
#2Nicole R. Villemarette-Pittman (LSU Health Sciences Center New Orleans)H-Index: 14
Last. Teresa C. Frohman (University of Texas at Austin)H-Index: 37
view all 9 authors...
Abstract The COVID-19 pandemic has produced a world-wide collapse of social and economic infrastructure, as well as constraining our freedom of movement. This respiratory tract infection is unprecedented in that it targets the most distal and highly vulnerable aspect of the human bronchopulmonary tree, specifically, the alveoli that are responsible for the loading of oxygen upon red cell hemoglobin for use by all of the body's tissues. In most symptomatic individuals, the reaction is a productiv...
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#1Rima El-Abassi (LSU: Louisiana State University)H-Index: 7
#2Michael Y. Soliman (LSU: Louisiana State University)H-Index: 3
Last. John D. England (LSU: Louisiana State University)H-Index: 34
view all 4 authors...
Abstract Introduction Stiff-person syndrome (SPS), first described in 1956 by Moersch and Woltman, is a progressive autoimmune disorder with core features of chronic fluctuating progressive truncal and limb rigidity and painful muscle spasms leading to gait difficulties, falls and an appearance that resembles tin soldiers. The syndrome is a rare, highly disabling disorder of the central nervous and frequently results in significant disability. Understanding of the etiology, clinical spectrum, di...
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#1Alexander B. Ramos (LSU Health Sciences Center New Orleans)H-Index: 3
#2Roberto Alejandro Cruz (LSU Health Sciences Center New Orleans)H-Index: 4
Last. Edward C. Mader (LSU Health Sciences Center New Orleans)H-Index: 5
view all 5 authors...
Refractory seizures or status epilepticus (RS/SE) continues to be a challenge in the inpatient setting. Failure to abort a seizure with antiepileptic drugs (AEDs) may lead to intubation and treatment with general anesthesia exposing patients to complications, extending hospitalization, and increasing the cost of care. Studies have shown a key role of inflammatory mediators in seizure generation and termination. We describe 4 patients with RS/SE that was aborted when dexamethasone was added to co...
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