A. M. Brena-Molina
Self-healing hydrogelsPathologyAdipose tissueExtracellular matrixImmunophenotypingMesenchymal stem cellPerichondriumMicrotiaElastic cartilageLimbal stem cellCytokeratinWound healingCartilageAmnionType II collagenStem cellTissue engineeringMedicineBiologyCell biology
6Publications
4H-index
35Citations
Publications 6
Newest
#2J. García-LópezH-Index: 3
Last. A. M. Brena-MolinaH-Index: 4
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Abstract In Mexico, burns are considered a public health problem; approximately 93% of all burned patients are treated at public hospitals. For patients undergoing extensive burns, prompt skin coverage avoids potential complications, is life-saving, and is the key for acceptable functional and aesthetic results. Many efforts have been undertaken to find new strategies for the treatment of burns. The aim of this study was to create a human Dermo-Epidermal Skin Substitute (hDE-SS) by combining het...
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#1Mario Alberto Pérez-Díaz (IPN: Instituto Politécnico Nacional)H-Index: 5
#1Mario Alberto Pérez-Díaz (IPN: Instituto Politécnico Nacional)H-Index: 2
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Background Treatment of severe or chronic skin wounds is an important challenge facing medicine and a significant health care burden. Proper wound healing is often affected by bacterial infection; where biofilm formation is one of the main risks and particularly problematic because it confers protection to microorganisms against antibiotics. One avenue to prevent bacterial colonization of wounds is the use of silver nanoparticles (AgNPs); which have proved to be effective against non-multidrug-r...
7 CitationsSource
The external ear is composed of elastic cartilage. Microtia is a congenital malformation of the external ear that involves a small reduction in size or a complete absence. The aim of tissue engineering is to regenerate tissues and organs clinically implantable based on the utilization of cells and biomaterials. Remnants from microtia represent a source of cells for auricular reconstruction using tissue engineering. To examine the macromolecular architecture of microtia cartilage and behavior of ...
4 CitationsSource
Skin wound repair requires the development of different kinds of biomaterials that must be capable of restoring the damaged tissue. Type I collagen and chitosan have been widely used to develop scaffolds for skin engineering because of their cell-related signaling properties such as proliferation, migration, and survival. Collagen is the major component of the skin extracellular matrix ECM, while chitosan mimics the structure of the native polysaccharides and glycosaminoglycans in the ECM. Chito...
4 CitationsSource
Human adipose-derived mesenchymal stem cells (hADMSCs) are believed to be potential key factors for starting the regenerative process after tissue injury. However, an efficient method of delivering these regenerative cells to an external wound site is still lacking. Human amnion and pig skin have long been used as skin wound dressings for the treatment of burns and other skin lesions. Herein, we present the generation of two constructs using these two biomaterials as effective scaffolds for the ...
14 CitationsSource
#2Leticia Vázquez-Maya (HGM: Hospital General de México)H-Index: 2
Last. Cristina VelasquilloH-Index: 11
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Several ocular diseases affect the corneal surface; the development of effective technologies for the treatment of corneal lesions has brought about an improvement in the quality of life of affected patients. The aim of this study is to culture and characterize limbal stem cells cultured on gamma (60Co) radiosterilized human amnion (RHA). Limbal stem cells were isolated from ten preserved samples of corneal transplant. The cells were cultured since primary culture until expanded cells on RHA and...
4 CitationsSource