Bilel Neili
Tunis University
IIfCA15-3CancerInternal medicinePathologyOncologymicroRNACase-control studyCellAnti-nuclear antibodyArtificial intelligencePattern recognitionAcquired immune systemCADImmunologyPathologicalCD146ImmunityComputer-aided diagnosisIL17AAutoimmunityFibrosisInflammatory breast cancerPulmonary fibrosisCirculating MicroRNAFluorescence intensityComputer aided detectionIndirect immunofluorescenceMirna profilingPotential biomarkersCandidate mirnasGold standard (test)Computer scienceReal-time polymerase chain reactionBreast cancerMedicineRAR-related orphan receptor gammaComputer hardwareCancer cell
Publications 5
Systemic sclerosis (SSc) is an autoimmune disorder characterized by vascular damage, excessive fibrosis and abnormal T cells immune-regulation. CD146 is an adhesion molecule essentially expressed in the vascular system, but also on TH17 lymphocytes. In view of the recently described role of CD146 in SSc, we hypothesized an involvement of CD146 positive TH17 cells in this disease. Compared to healthy controls, we showed that both soluble form of CD146 (sCD146), and IL17A levels were increased in ...
#1Khouloud Hamdi (Tunis University)H-Index: 4
#2Jan BlancatoH-Index: 19
Last. Raja MarrakchiH-Index: 18
view all 13 authors...
: Recent discovery showing the presence of microRNAs (miRNAs) in the circulation sparked interest in their use as potential biomarkers. Our previous studies showed the diagnostic potential of miR-451 as a serological marker for inflammatory breast cancer (IBC), miR-337- 5p and miR-30b for non-inflammatory breast cancer (non-IBC). The aim of this study is to investigate the prognostic values of circulating miRNAs by comparing the amounts of 12 circulating miRNAs in the serum of IBC and non-IBC fr...
#1Amel Benammar Elgaaied (Tunis University)H-Index: 21
#2Donato Cascio (University of Palermo)H-Index: 13
Last. Giuseppe RasoH-Index: 65
view all 39 authors...
Antinuclear antibodies (ANAs) are significant biomarkers in the diagnosis of autoimmune diseases in humans, done by mean of Indirect ImmunoFluorescence (IIF) method, and performed by analyzing patterns and fluorescence intensity. This paper introduces the AIDA Project (autoimmunity: diagnosis assisted by computer) developed in the framework of an Italy-Tunisia cross-border cooperation and its preliminary results. A database of interpreted IIF images is being collected through the exchange of ima...
#1Khouloud Hamdi (Tunis University)H-Index: 4
#2David Goerlitz (GUMC: Georgetown University Medical Center)H-Index: 10
Last. Raja Marrakchi (Tunis University)H-Index: 18
view all 13 authors...
In recent years, circulating miRNAs have attracted interest as stable, non-invasive biomarkers for various pathological conditions. Here, we investigated their potential to serve as minimally invasive, early detection markers for inflammatory breast cancer (IBC) and non-inflammatory breast cancer (non-IBC) in serum. miRNA profiling was performed on serum from 20 patients with non-IBC, 20 with IBC, and 20 normal control subjects. Real-time reverse transcription-polymerase chain reaction (qRT-PCR)...
view all 32 authors...
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