Jonathan Rodriguez
Lyon College
PathologyAdipose tissueChemistryMetabolic pathwayMesenchymal stem cellGlycolysisNS5ALeukapheresisHexokinaseWound healingStromal vascular fractionType II collagenStem cellTransplantationChondrogenesisFlow cytometryAnaerobic glycolysisMedicineBiologyCell biology
Publications 8
#1Hugo Fabre (University of Lyon)H-Index: 6
#2Maxime Ducret (University of Lyon)H-Index: 9
Last. Frédéric Mallein-Gerin (University of Lyon)H-Index: 25
view all 11 authors...
Mesenchymal stem cells (MSCs) represent alternative candidates to chondrocytes for cartilage engineering. However, it remains difficult to identify the ideal source of MSCs for cartilage repair since conditions supporting chondrogenic induction are diverse among published works. In this study, we characterized and evaluated the chondrogenic potential of MSCs from bone marrow (BM), Wharton’s jelly (WJ), dental pulp (DP), and adipose tissue (AT) isolated and cultivated under serum-free conditions....
12 CitationsSource
#1Jonathan Rodriguez (Lyon College)H-Index: 4
#2Anne-Sophie PrattaH-Index: 1
Last. Ali Mojallal (Lyon College)H-Index: 1
view all 12 authors...
Adipose-derived stem/stromal cells (ASCs) reside in the stromal vascular fraction (SVF) of adipose tissue (AT) and can be easily isolated. However, extraction of the SVF from lipoaspirate is a critical step in generating ASC, and semiautomated devices have been developed to enhance the efficacy and reproducibility of the outcomes and to decrease manipulation and contamination. In this study, we compared the reference method used in our lab for SVF isolation from lipoaspirate, with three medical ...
15 CitationsSource
#1Hugo Fabre (Lyon College)H-Index: 6
#2M. Ducret (Lyon College)
Last. Frédéric Mallein-Gerin (Lyon College)H-Index: 25
view all 11 authors...
#1Jonathan Rodriguez (French Institute of Health and Medical Research)H-Index: 4
#2F Boucher (University of Lyon)H-Index: 6
Last. Ali Mojallal (French Institute of Health and Medical Research)H-Index: 1
view all 10 authors...
Background The use of stem cells from adipose tissue or adipose-derived stem cells (ASCs) in regenerative medicine could be an interesting alternative to bone marrow stem cells because they are easily accessible and available in large quantities. The aim of this study was to evaluate the potential effect of ASCs on the healing of 12 mm diameter-excisional wounds (around 110 mm2) in nude mice.
35 CitationsSource
#1X. MatillonH-Index: 5
#2Edouard Baulier (French Institute of Health and Medical Research)H-Index: 4
Last. Lionel BadetH-Index: 39
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Objectifs Le phenomene d’ischemie-reperfusion (IR) est un processus central implique dans la dysfonction aigue et chronique du greffon renal. L’objectif de cette etude etait de caracteriser les cellules souches mesenchymateuses du tissu adipeux (TA) porcin (pASC) et leurs capacites a ameliorer la reprise de fonction des greffons dans des conditions mimant la situation des donneurs decedes apres arret cardiaque (DDAC). Methodes La morphologie, la proliferation, le phenotype en cytometrie de flux ...
#1X. MatillonH-Index: 1
#1X. MatillonH-Index: 5
Last. Lionel BadetH-Index: 39
view all 9 authors...
#1Olivier HequetH-Index: 19
#2Q.H. LeH-Index: 2
Last. B. CoiffierH-Index: 46
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Abstract Hematopoietic stem cells (HSCs) required to perform peripheral hematopoietic autologous stem cell transplantation (APBSCT) can be collected by processing several blood volumes (BVs) in leukapheresis sessions. However, this may cause granulocyte harvest in graft and decrease in patient's platelet blood level. Both consequences may induce disturbances in patient. One apheresis team's current purpose is to improve HSC collection by increasing HSC collection and prevent increase in granuloc...
#1Christophe RamièreH-Index: 16
#2Jonathan RodriguezH-Index: 4
Last. Olivier DiazH-Index: 3
view all 6 authors...
The study of cellular central carbon metabolism modulations induced by viruses is an emerging field. Human cytomegalovirus (HCMV), herpes simplex virus (HSV), Kaposi's sarcoma-associated herpesvirus (KSHV), and hepatitis C virus (HCV) have been shown recently to reprogram cell metabolism to support their replication. During HCV infection the global glucidolipidic metabolism of hepatocytes is highly impacted. It was suggested that HCV might modify glucose uptake and glycolysis to increase fatty a...
55 CitationsSource