Sandra A. Brown
University of California, San Diego
PsychiatryDevelopmental psychologyDeforestationPsychologyCognitionEcologyInjury preventionYoung adultAbstinenceAlcohol abuseSubstance usePoison controlEnvironmental scienceSubstance abuseGreenhouse gasAgroforestryCarbon cycleClinical psychologyMedicineForestry
Publications 428
#1Krista M. Lisdahl (UWM: University of Wisconsin–Milwaukee)H-Index: 15
#2Susan F. Tapert (UCSD: University of California, San Diego)H-Index: 88
view all 112 authors...
Abstract null null Background null The Adolescent Brain Cognitive Development ™ Study (ABCD StudyⓇ) is an open-science, multi-site, prospective, longitudinal study following over 11,800 9- and 10-year-old youth into early adulthood. The ABCD Study aims to prospectively examine the impact of substance use (SU) on neurocognitive and health outcomes. Although SU initiation typically occurs during teen years, relatively little is known about patterns of SU in children younger than 12. null null null...
#1William E. Pelham (UCSD: University of California, San Diego)H-Index: 1
#2Susan F. Tapert (UCSD: University of California, San Diego)H-Index: 88
Last. Gayathri J. Dowling (NIDA: National Institute on Drug Abuse)H-Index: 10
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PURPOSE Evaluate changes in early adolescent substance use during the coronavirus disease 2019 (COVID-19) pandemic using a prospective, longitudinal, nationwide cohort. METHODS Participants were enrolled in the Adolescent Brain Cognitive Development Study. A total of 7,842 youth (mean age = 12.4 years, range = 10.5-14.6) at 21 study sites across the U.S. completed a three-wave assessment of substance use between May and August 2020. Youth reported whether they had used alcohol, nicotine, cannabi...
#1Scott A Funkhouser (CU: University of Colorado Boulder)
#2Jason D. Boardman (CU: University of Colorado Boulder)H-Index: 50
Last. Luke M. Evans (CU: University of Colorado Boulder)H-Index: 16
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The genetic architecture of numerous smoking behaviors is highly polygenic, but these genetic effects are heterogeneous and depend on moderating factors. Here, we used common SNPs from the UK Biobank to investigate heterogeneous genetic effects for smoking heaviness using cigarettes per day (CPD) records, smoking initiation (SI), and smoking cessation (SC). We assessed heterogeneous effects across levels of sex, age of smoking initiation, major depressive disorder (MDD) DSM-V-like diagnosis, gen...
#1Alejandro D. Meruelo (UCSD: University of California, San Diego)H-Index: 7
#2Ty Brumback (Northern Kentucky University)H-Index: 15
Last. Susan F. Tapert (UCSD: University of California, San Diego)H-Index: 88
view all 6 authors...
#1Bader Chaarani (UVM: University of Vermont)H-Index: 12
#2S Hahn (UVM: University of Vermont)H-Index: 1
Last. Matthew D. Albaugh (UVM: University of Vermont)H-Index: 21
view all 192 authors...
The Adolescent Brain Cognitive Development (ABCD) Study® is a 10-year longitudinal study of children recruited at ages 9 and 10. A battery of neuroimaging tasks are administered biennially to track neurodevelopment and identify individual differences in brain function. This study reports activation patterns from functional MRI (fMRI) tasks completed at baseline, which were designed to measure cognitive impulse control with a stop signal task (SST; N = 5,547), reward anticipation and receipt with...
2 CitationsSource
#1Ty BrumbackH-Index: 15
#2Wesley K. ThompsonH-Index: 68
Last. Susan F. TapertH-Index: 88
view all 5 authors...
Many psychosocial factors have been implicated in the onset and escalation of substance use in adolescence and young adulthood. Typically, each factor explains a small amount of the variance in substance use outcomes, and effects are typically applied across a broad range of ages or computed from cross-sectional data. The current study evaluated the association of factors including social influence (e.g., peer substance use), cognitive features (e.g., alcohol expectancies), and personality and e...
#1Yi Li (UCSF: University of California, San Francisco)H-Index: 94
#2Wesley K. Thompson (UCSD: University of California, San Diego)H-Index: 68
Last. Sandra A. Brown (UCSD: University of California, San Diego)H-Index: 124
view all 109 authors...
Importance Incidental findings (IFs) are unexpected abnormalities discovered during imaging and can range from normal anatomic variants to findings requiring urgent medical intervention. In the case of brain magnetic resonance imaging (MRI), reliable data about the prevalence and significance of IFs in the general population are limited, making it difficult to anticipate, communicate, and manage these findings. Objectives To determine the overall prevalence of IFs in brain MRI in the nonclinical...
1 CitationsSource
#1Qingyu Zhao (Stanford University)H-Index: 8
#2Edith V. Sullivan (Stanford University)H-Index: 111
Last. Kilian M. Pohl (Stanford University)H-Index: 27
view all 17 authors...
Importance Maturation of white matter fiber systems subserves cognitive, behavioral, emotional, and motor development during adolescence. Hazardous drinking during this active neurodevelopmental period may alter the trajectory of white matter microstructural development, potentially increasing risk for developing alcohol-related dysfunction and alcohol use disorder in adulthood. Objective To identify disrupted adolescent microstructural brain development linked to drinking onset and to assess wh...
4 CitationsSource
#1Jarrod M. Ellingson (CU: University of Colorado Boulder)H-Index: 13
#2J. Megan Ross (CU: University of Colorado Boulder)H-Index: 8
Last. Christian J. Hopfer (CU: University of Colorado Boulder)H-Index: 48
view all 11 authors...
Aims To examine whether moderate adolescent cannabis use has neurocognitive effects that are unexplained by familial confounds, which prior family-controlled studies may not have identified. Design A quasi-experimental, sibling-comparison design was applied to a prospective, observational study of adolescents with moderate cannabis use. Participants were recruited from 2001 to 2006 (mean age = 17 years). A second wave of data was collected from 2008 to 2013 (mean age = 24 years). Setting Two US ...
2 CitationsSource
#1Alejandro D. Meruelo (UCSD: University of California, San Diego)H-Index: 7
#2Ty Brumback (Northern Kentucky University)H-Index: 15
Last. Susan F. Tapert (UCSD: University of California, San Diego)H-Index: 88
view all 6 authors...
Abstract Background Adolescents are at increased risk of developing major depressive disorder (MDD) than many other age groups. Although the neural correlates of MDD in adults have been studied prospectively, such adolescent depression studies are mainly cross-sectional. We extracted data regarding the relationship between cortical thickness and later development of adolescent MDD from a national community study that uses an accelerated longitudinal design to examine the psychological, environme...