Sandra A. Brown
University of California, San Diego
PsychiatryDevelopmental psychologyDeforestationPsychologyCognitionEcologyInjury preventionYoung adultAbstinenceAlcohol abuseSubstance usePoison controlEnvironmental scienceSubstance abuseGreenhouse gasAgroforestryCarbon cycleClinical psychologyMedicineForestry
Publications 432
#1Delin Sun (Duke University)H-Index: 11
#2Viraj Adduru (RIT: Rochester Institute of Technology)H-Index: 5
Last. Rajendra A. Morey (Duke University)H-Index: 34
view all 16 authors...
Objective: Cortical thickness changes dramatically during development and is influenced by adolescent drinking. However, previous findings have been inconsistent and limited by region-of-interest approaches that are underpowered because they do not conform to the underlying heterogeneity from the effects of alcohol. Methods: Adolescents (n=657; 12-22 years at baseline) from the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) who endorsed little to no alcohol use at ba...
#1Ty BrumbackH-Index: 15
#2Wesley K. ThompsonH-Index: 71
Last. Susan F. TapertH-Index: 87
view all 5 authors...
Many psychosocial factors have been implicated in the onset and escalation of substance use in adolescence and young adulthood. Typically, each factor explains a small amount of the variance in substance use outcomes, and effects are typically applied across a broad range of ages or computed from cross-sectional data. The current study evaluated the association of factors including social influence (e.g., peer substance use), cognitive features (e.g., alcohol expectancies), and personality and e...
#1Yi Li (UCSF: University of California, San Francisco)H-Index: 94
#2Wesley K. Thompson (UCSD: University of California, San Diego)H-Index: 71
Last. Sandra A. Brown (UCSD: University of California, San Diego)H-Index: 124
view all 109 authors...
Importance Incidental findings (IFs) are unexpected abnormalities discovered during imaging and can range from normal anatomic variants to findings requiring urgent medical intervention. In the case of brain magnetic resonance imaging (MRI), reliable data about the prevalence and significance of IFs in the general population are limited, making it difficult to anticipate, communicate, and manage these findings. Objectives To determine the overall prevalence of IFs in brain MRI in the nonclinical...
#1Maria Alejandra Infante (UCSD: University of California, San Diego)H-Index: 2
#2Ye Zhang (UCSD: University of California, San Diego)H-Index: 1
Last. Wes Thompson (UCSD: University of California, San Diego)H-Index: 5
view all 18 authors...
The age- and time-dependent effects of binge-drinking on adolescent brain development have not been well characterized even though binge drinking is a health crisis among adolescents. The impact of binge drinking on gray matter volume development was examined using longitudinal data from the National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA). Non-binge drinkers (n=177) were matched to binge drinkers (n=164) on potential confounders. Number of binge drinking episodes in t...
#1Qingyu Zhao (Stanford University)H-Index: 7
#2Edith V. Sullivan (Stanford University)H-Index: 111
Last. Kilian M. Pohl (Stanford University)H-Index: 29
view all 17 authors...
Importance Maturation of white matter fiber systems subserves cognitive, behavioral, emotional, and motor development during adolescence. Hazardous drinking during this active neurodevelopmental period may alter the trajectory of white matter microstructural development, potentially increasing risk for developing alcohol-related dysfunction and alcohol use disorder in adulthood. Objective To identify disrupted adolescent microstructural brain development linked to drinking onset and to assess wh...
1 CitationsSource
#1Jarrod M. Ellingson (CU: University of Colorado Boulder)H-Index: 13
#2J. Megan Ross (CU: University of Colorado Boulder)H-Index: 9
Last. Christian J. Hopfer (CU: University of Colorado Boulder)H-Index: 50
view all 11 authors...
Aims To examine whether moderate adolescent cannabis use has neurocognitive effects that are unexplained by familial confounds, which prior family-controlled studies may not have identified. Design A quasi-experimental, sibling-comparison design was applied to a prospective, observational study of adolescents with moderate cannabis use. Participants were recruited from 2001 to 2006 (mean age = 17 years). A second wave of data was collected from 2008 to 2013 (mean age = 24 years). Setting Two US ...
1 CitationsSource
#1Peter M. OdorH-Index: 9
#2S. BampoeH-Index: 11
Last. A. WickhamH-Index: 1
view all 751 authors...
There are no current descriptions of general anaesthesia characteristics for obstetric surgery, despite recent changes to patient baseline characteristics and airway management guidelines. This analysis of data from the direct reporting of awareness in maternity patients' (DREAMY) study of accidental awareness during obstetric anaesthesia aimed to describe practice for obstetric general anaesthesia in England and compare with earlier surveys and best-practice recommendations. Consenting patients...
10 CitationsSource
#1Alejandro D. Meruelo (UCSD: University of California, San Diego)H-Index: 7
#2Ty Brumback (Northern Kentucky University)H-Index: 15
Last. Susan F. Tapert (UCSD: University of California, San Diego)H-Index: 87
view all 6 authors...
Abstract Background Adolescents are at increased risk of developing major depressive disorder (MDD) than many other age groups. Although the neural correlates of MDD in adults have been studied prospectively, such adolescent depression studies are mainly cross-sectional. We extracted data regarding the relationship between cortical thickness and later development of adolescent MDD from a national community study that uses an accelerated longitudinal design to examine the psychological, environme...
#1Qingyu Zhao (Stanford University)H-Index: 7
#2Edith V. Sullivan (Stanford University)H-Index: 111
Last. Kilian M. Pohl (Stanford University)H-Index: 29
view all 22 authors...
: Exogenous causes, such as alcohol use, and endogenous factors, such as temperament and sex, can modulate developmental trajectories of adolescent neurofunctional maturation. We examined how these factors affect sexual dimorphism in brain functional networks in youth drinking below diagnostic threshold for alcohol use disorder (AUD). Based on the 3-year, annually acquired, longitudinal resting-state functional magnetic resonance imaging (MRI) data of 526 adolescents (12-21 years at baseline) fr...
#1Kevin CumminsH-Index: 21
#2Kate B. NoonerH-Index: 9
Last. Sandra A. BrownH-Index: 124
view all 11 authors...
Background: Longitudinal studies of many health behaviors often rely on infrequent self-report assessments. The measurement of psychoactive substance use among youth is expected to improve with more frequent mobile assessments, which can reduce recall bias. Researchers have used mobile devices for longitudinal research, but studies that last years and assess youth continuously at a fine-grained, temporal level (eg, weekly) are rare. A tailored mobile app (mNCANDA [mobile National Consortium on A...