Cheng Peng
Chengdu University of Traditional Chinese Medicine
PharmacokineticsInternal medicineEnantioselective synthesisCatalysisOrganic chemistryChemistryTraditional Chinese medicineApoptosisIn vitroIn vivoCombinatorial chemistryChromatographyCancer researchBiochemistryTraditional medicineOrganocatalysisStereochemistryMedicineBiologyPharmacology
274Publications
33H-index
4,066Citations
Publications 303
Newest
#1Guan-Ru Chen (CDUTCM: Chengdu University of Traditional Chinese Medicine)
#2Xiao-Fang Xie (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 8
Last. Cheng Peng (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 33
view all 8 authors...
Abstract null null Ethnopharmacological relevance null Essential oil (EO) is the main extract of patchouli and tangerine peel with antiinflammatory, antiulcer, and other functions. However, the efficacy and mechanism of the combination of EO from patchouli and tangerine peel against gastric ulcer (GU) are unclear. null null null Aim of the study null This study aims to reveal the protective effect of the combination of EO from patchouli and tangerine peel against GU in rats, as well as explore t...
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#2Chun-Wang MengH-Index: 6
Last. Ou DaiH-Index: 5
view all 10 authors...
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#1Jiang Jialuo (CDUTCM: Chengdu University of Traditional Chinese Medicine)
#2Yan Huang (CDUTCM: Chengdu University of Traditional Chinese Medicine)
Last. Chaolong Rao (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 3
view all 12 authors...
Abstract: null null Ethnopharmacological relevance null Zanthoxylum armatum DC is a traditional medicinal plant. It is widely used in clinical treatment and disease prevention in China, India and other regions. Modern studies have reported the phytotoxicity, cytotoxicity and the animal toxicity of Zanthoxylum armatum DC, and the damage of genetic material has been observed in plants, but the detailed mechanism has not been explored. Besides, the toxicity of normal mammalian cells has not been ev...
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#1Wuwen Feng (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 15
#2Juan Liu (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 3
Last. Cheng Peng (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 33
view all 4 authors...
Chinese medicines (CM) are gaining more attentions from all over the world. However, there are a large body of questions to be answered because of the chemical complexity of CM and intricate molecular reactions within human body. In recent years, gut microbiota and metabolomics have emerged as two cynosures in deciphering the mechanisms of how our body is functioning. Since gut microbiota and host is a closely interrelated system, paying attention only to gut microbiota or metabolites may omit t...
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#1Li LiaoH-Index: 1
#2Mengting ZhouH-Index: 1
Last. Yunxia LiH-Index: 11
view all 8 authors...
Thrombosis is a general pathological phenomenon during severe disturbances to homeostasis, which plays an essential role in cardiovascular and cerebrovascular diseases. Leonurine (LEO), isolated from Leonurus japonicus Houtt, showed a crucial role in anticoagulation and vasodilatation. However, the properties and therapeutic mechanisms of this effect have not yet been systematically elucidated. In this study, the antithrombotic effect of LEO was investigated in AH-induced thrombosis in zebrafish...
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#1Tao Yang (Sichuan University)H-Index: 10
#2Huidong Li (Xihua University)H-Index: 10
Last. Youfu Luo (Sichuan University)H-Index: 20
view all 9 authors...
Abstract null null Reversible chemically stimulated cyclization/cycloreversion reactions are of great interest and highly demanding for developing molecular switches, such as fluorescent probes. Herein, ultrafast and reversible cyclization/cycloreversion reactions of 4-imino-4H-quinolizine-1-carbonitrile (IMQU) derivatives, induced by H+/OH−, were developed as a new strategy for pH sensing. 1H NMR, HRMS techniques and quantum chemical methods applied to the pH sensing behavior of IMQUs reveal it...
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#1Huan Zhu (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 2
#2Ou Dai (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 5
Last. Cheng Peng (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 33
view all 11 authors...
Abstract null null Lung cancer is one of the most malignant tumors with the highest mortality and morbidity. The tubers of Bletilla striata are known as “an excellent medicine for lung diseases” in traditional Chinese medicine. This study performed a targeted study to explore compounds with anti-lung cancer activity and the molecular mechanisms using A549 cells. Eighteen bibenzyl derivatives, including four new compounds (13, 14, 16, and 18), were isolated from the tubers of B. striata. Analysis...
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#1Hao Cheng (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 1
#2Juan Liu (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 5
Last. Cheng Peng (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 33
view all 5 authors...
Abstract null null Berberine (BBR), an isoquinoline alkaloid, has been found in many plants, such as Coptis chinensis Franch. and Phellodendron chinense Schneid. Although BBR has a wide spectrum of pharmacological effects, its oral bioavailability is extremely low. In recent years, gut microbiota has emerged as a cynosure to understand the mechanisms of action of herbal compounds. Numerous studies have demonstrated that, due to its low bioavailability, BBR can interact with the gut microbiota, t...
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#1Qing Mao (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 3
#2Qian Zhao (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 7
Last. Gu Zhan (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 3
view all 11 authors...
Though numerous cyanation reactions have been developed for the synthesis of benzonitriles, the construction of valuable fully substituted benzonitriles is still a challenging task. Herein, we reported a tertiary amine-catalyzed [3 + 3]-benzannulation for the green synthesis of CF3-functionalized fully substituted benzonitriles. This strategy features exclusive chemoselectivity, high atom-economy, and good step-economy with environment-friendly reagents and mild conditions. Unique triphenyl-subs...
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#1Xinyan Xue (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 2
#2Ying Deng (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 2
Last. Yunxia Li (CDUTCM: Chengdu University of Traditional Chinese Medicine)H-Index: 11
view all 8 authors...
Abstract null null Background null Atherosclerosis is a chronic vascular inflammatory disease with complex pathogenesis. Its serious consequence is insufficient blood supply to heart and brain, which eventually leads to myocardial ischemia, infarction and stroke. Hydroxysafflor yellow A (HSYA), a single chalcone glycoside compound with a variety of pharmacological effects, which has shown a potential biological activity for prevention and treatment of atherosclerosis. null null null Purpose null...
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