N. To
University of Leeds
Internal medicineSurgeryOdds ratioIntensive care medicinePhysical therapyCyclic vomiting syndromeSmoking cessationFunctional gastrointestinal disorderIrritable bowel syndromeColonoscopyDiseaseCrohn's diseaseMEDLINENauseaVomitingCrohn diseaseDiagnostic evaluationRisk factorLatent class modelMedicineGastroenterologyMeta-analysis
24Publications
7H-index
392Citations
Publications 14
Newest
#1Raguprakash Ratnakumaran (University of Leeds)H-Index: 5
#2N. To (University of Leeds)H-Index: 7
Last. P John Hamlin (University of Leeds)H-Index: 12
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AbstractObjectives: Recently, the infliximab biosimilar (CT-P13) received market authorisation for inflammatory bowel disease (IBD), allowing cost benefits when switching to CT-P13. We aim to assess the efficacy and safety of switching from originator infliximab to CT-P13 for new and existing patients.Material and methods: Treatment response, remission, primary and secondary loss of response rates, and adverse events in patients who initiated infliximab originator in the 12 months pre-switch (n ...
19 CitationsSource
#1Rebecca C Sagar (University of Leeds)H-Index: 4
#1Rebecca Sagar (St James's University Hospital)H-Index: 5
Last. Alexander C. Ford (St James's University Hospital)H-Index: 86
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Background Cyclic vomiting syndrome (CVS) is a functional gastrointestinal disorder (FGID) characterized by intermittent episodes of nausea and vomiting. Our aim was to report its prevalence and associated features. Methods Data concerning demographics, symptoms, and psychiatric comorbidity were collected. Symptoms compatible with CVS were classified as per Rome III criteria. We recorded whether a diagnosis of CVS was considered in patients after negative investigation. We compared demographics ...
17 CitationsSource
#1Rebecca C SagarH-Index: 4
#1Rebecca Sagar (St James's University Hospital)H-Index: 5
Last. Alexander C. FordH-Index: 86
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Introduction Cyclic vomiting syndrome (CVS) is a functional gastrointestinal disorder (FGID) whose aetiology is poorly understood. It is characterised by acute episodes of vomiting and nausea followed by asymptomatic periods. Average age of symptom onset in adults is 22 years but average age of diagnosis is 31 years. This delay is probably because, until recently, CVS was considered to be a paediatric condition. Few studies have reported the prevalence in adults or risk factors for CVS. We exami...
Source
#1Ruchit Sood (University of Leeds)H-Index: 13
#2David J. Gracie (University of Leeds)H-Index: 16
Last. Graham R. Law (University of Leeds)H-Index: 28
view all 9 authors...
Source
#1Ruchit Sood (University of Leeds)H-Index: 13
#2David J. Gracie (University of Leeds)H-Index: 16
Last. Graham R. Law (University of Leeds)H-Index: 28
view all 9 authors...
BACKGROUND: The accuracy of symptom-based diagnostic criteria for irritable bowel syndrome (IBS) is modest. AIMS: To derive and validate a new test that utilises latent class analysis. METHODS: Symptom, colonoscopy, and histology data were collected from 1981 patients and 360 patients in two cohorts referred to secondary care for investigation of their gastrointestinal symptoms in Canada and the UK, respectively. Latent class analysis was used to identify naturally occurring clusters in patient-...
8 CitationsSource
#1Ruchit SoodH-Index: 13
#2Michael CamilleriH-Index: 146
Last. Alexander C. Ford (St James's University Hospital)H-Index: 86
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Enhancing Diagnostic Performance of Symptom-Based Criteria for Irritable Bowel Syndrome by Additional History and Limited Diagnostic Evaluation
25 CitationsSource
#1N. To (St James's University Hospital)H-Index: 7
#2David J. Gracie (St James's University Hospital)H-Index: 16
Last. Alexander C. Ford (St James's University Hospital)H-Index: 86
view all 3 authors...
7 CitationsSource
#1Ruchit Sood (University of Leeds)H-Index: 13
#2Michael Camilleri (Mayo Clinic)H-Index: 146
Last. Alexander C. Ford (University of Leeds)H-Index: 86
view all 7 authors...
Introduction Symptom-based criteria to diagnose irritable bowel syndrome (IBS) positively perform only modestly. Our aim was to assess whether including other items from the clinical history and diagnostic workup improves their performance. Methods We collected complete symptom, colonoscopy, and histology data from 318 consecutive, unselected adult patients with lower gastrointestinal (GI) symptoms in secondary care. The reference standard used to define presence of true IBS was patient-reported...
Source
#1N. To (University of Leeds)H-Index: 7
#2David J. Gracie (University of Leeds)H-Index: 16
Last. Alexander C. Ford (University of Leeds)H-Index: 86
view all 3 authors...
Source
#1N. To (University of Leeds)H-Index: 7
#2David J. Gracie (University of Leeds)H-Index: 16
Last. Alexander C. Ford (University of Leeds)H-Index: 86
view all 3 authors...
Source