Hiroyuki Tanaka
Okayama University
Internal medicineRadiologyEndocrinologyBalloonSurgeryCardiologyChemistryImmunologyDrug-eluting stentSirolimusRestenosisStentAngioplastyPercutaneous coronary interventionIn patientStent implantationConventional PCIMyocardial infarctionMedicineBiology
604Publications
43H-index
5,824Citations
Publications 618
Newest
OBJECTIVE Gynecomastia is a benign proliferation of the glandular breast tissue in men and is generally caused by a decrease in androgen and an increase in estrogen. Diabetes has been reported to be a risk factor for lowering androgen levels. Moreover, lowered androgen levels are more common in older men. In the present study, we aimed to evaluate the signals for gynecomastia in older men on antidiabetic medications. MATERIALS AND METHODS A disproportionality analysis was performed to detect the...
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#1Tomotsugu Seki (Kyoto University)H-Index: 3
#2Hironobu TokumasuH-Index: 6
Last. Koji Kawakami (Kyoto University)H-Index: 36
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Background null The appropriateness of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) lesions has rarely been investigated.Methods and Results:The Japanese CTO-PCI Expert Registry enrolled consecutive patients undergoing CTO-PCI carried out by highly experienced Japanese CTO specialists who performed more than 50 CTO-PCIs per year and 300 CTO-PCIs in total. This study included patients undergoing CTO-PCI between January 2014 and December 2019. The appropriateness, tre...
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#2Shunsuke KuboH-Index: 7
Last. Takeshi TadaH-Index: 15
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Abstract null null Background null Mechanical circulatory support (MCS) is essential to maintain the hemodynamics in selected patients with cardiogenic shock (CS). However, little is known about predictors and clinical impact of device-related complications on clinical outcomes in patients with MCS. null null null Methods null We retrospectively reviewed consecutive 477 patients who received veno-arterial extracorporeal membrane oxygenation (VA-ECMO), Impella (Abiomed, Danvers, MA, USA), and int...
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#1Karine BriotH-Index: 35
#2Anthony A. Portale (UCSF: University of California, San Francisco)H-Index: 47
Last. Steven W. Ing (The Ohio State University Wexner Medical Center)H-Index: 1
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Objectives null To report the impact of burosumab on patient-reported outcomes (PROs) and ambulatory function in adults with X-linked hypophosphataemia (XLH) through 96 weeks. null Methods null Adults diagnosed with XLH were randomised 1:1 in a double-blinded trial to receive subcutaneous burosumab 1 mg/kg or placebo every 4 weeks for 24 weeks (NCT02526160). Thereafter, all subjects received burosumab every 4 weeks until week 96. PROs were measured using the Western Ontario and the McMaster Univ...
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#1Takeshi TadaH-Index: 15
#2Katsuya MiuraH-Index: 7
Last. Hiroyuki TanakaH-Index: 43
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BACKGROUND Calcified nodules (CN) has been reported to be associated with stent failure including in-stent restenosis (ISR). However, there is no systematic study of this condition. AIMS We aimed to clarify the prevalence, predictors, and midterm results of ISR lesions with CN. METHODS We examined the clinical characteristics of 651 ISR lesions which underwent percutaneous coronary intervention (PCI) with optical coherence tomography between October 2008 and July 2016, and their 6- to 8-month fo...
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#2Kiyotaka Nagahama (Kyorin University)H-Index: 19
Last. Makoto AoyagiH-Index: 5
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We report a case of membranous nephropathy (MN) in a patient with tuberculosis infection and lung adenocarcinoma. A 50-year-old Filipino woman underwent a renal biopsy for the evaluation of proteinuria and hematuria. Immunofluorescence analysis revealed positive staining of IgG in the glomerular basement membrane and mesangial matrices, while electron microscopy demonstrated the presence of sub-epithelial deposits, suggesting MN. To screen for secondary causes of MN, we conducted a computed tomo...
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#1Kosei Hasegawa (Okayama University)H-Index: 10
#2Hiroyuki Tanaka (Okayama University)H-Index: 43
Last. Hirokazu Tsukahara (Okayama University)H-Index: 39
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Pathogenic-activating variants of interferon induced with Helicase C domain 1 (IFIH1) cause Singleton-Merten (S-M) syndrome, which accompanies acro-osteolysis, loss of permanent teeth, and aortic calcification, as well as causing Aicardi-Goutieres (A-G) syndrome, which shows progressive encephalopathy, spastic paraplegia, and calcification of basal ganglia. Recently, patients with overlapping syndromes presenting with features of S-M syndrome and A-G syndrome were reported. However, progression ...
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#1Nobuhisa MorimotoH-Index: 2
#2Kiyotaka Nagahama (Kyorin University)H-Index: 19
Last. Suguru HirasawaH-Index: 6
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We report a case of nail-patella syndrome (NPS) with unusual thinning of the glomerular basement membrane (GBM) associated with a novel heterozygous variant in the LMX1B gene. A 43-year-old female patient with a previous diagnosis of NPS, referred to our hospital for persistent proteinuria, underwent a renal biopsy, which revealed minor glomerular abnormalities. She underwent a second renal biopsy at the age of 56 owing to the presence of persistent proteinuria and decline in serum albumin, meet...
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We report a case of acute ischemic nephropathy in a patient with severe renal artery stenosis and bradycardia due to sick sinus syndrome. An 83-year-old Japanese woman with a history of hypertension was diagnosed with sick sinus syndrome and scheduled for pacemaker implantation. Four days prior to admission for the procedure, she experienced sudden-onset severe right flank pain that persisted for 1 day. On the day of admission, her serum creatinine level increased from 1.35 mg/dL, measured 2 wee...
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Background null Percutaneous coronary intervention (PCI) for coronary bifurcation lesions using the 2-stent strategy remains a challenging procedure for interventionalists because of the higher incidence of in-stent restenosis (ISR) and adverse events. ISR predictors in patients treated with newer-generation everolimus-eluting stents (EES) and the 2-stent strategy remain unknown. Hence, we aimed to evaluate the 1-year clinical and angiographic outcomes of non-left main trunk (LMT) bifurcation le...
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