Puja B. Parikh
Stony Brook University
Internal medicineSurgeryOdds ratioCardiologyIntensive care medicineEmergency medicineHeart failureCoronary artery diseaseDiseaseStenosisValve replacementPercutaneous coronary interventionPopulationIn patientTranscatheter aorticConfidence intervalConventional PCIMyocardial infarctionStrokeMedicineMeta-analysis
130Publications
15H-index
773Citations
Publications 127
Newest
#1Thomas V. Bilfinger (SBU: Stony Brook University)H-Index: 41
#2Allison Nemesure (SBU: Stony Brook University)H-Index: 1
Last. Ting-Yu Wang (SBU: Stony Brook University)H-Index: 2
view all 0 authors...
Background. The clinical impact of the distressed communities index (DCI), a composite measure of economic well-being based on the U.S. zip code, is becoming increasingly recognized. Ranging from 0 (prosperous) to 100 (distressed), DCI’s association with cardiovascular outcomes remains unknown. We aimed to study the association of the DCI with presentation and outcomes in adults with severe symptomatic aortic stenosis (AS) undergoing transcatheter aortic valve intervention (TAVR) in an affluent ...
Source
#1Jignesh K. Patel (SBU: Stony Brook University)H-Index: 6
#2Elinor Schoenfeld (SBU: Stony Brook University)H-Index: 20
Last. Gerald C. Smaldone (SBU: Stony Brook University)H-Index: 36
view all 9 authors...
BACKGROUND While inhaled nitric oxide (iNO) has revealed benefit in cardiac arrest in an animal model, no published data has yet demonstrated the impact of iNO in humans with cardiac arrest. METHODS In this pilot study, we administered iNO, along with standard post-resuscitative care, in adults with in-hospital cardiac arrest (IHCA) following achievement of return of spontaneous circulation (ROSC) at an academic tertiary medical center. Patients receiving iNO were compared to age-matched control...
Source
Source
#1Jaffar M. Khan (MedStar Washington Hospital Center)H-Index: 4
#1Jaffar M. Khan (MedStar Washington Hospital Center)H-Index: 19
Last. Ron Waksman (MedStar Washington Hospital Center)H-Index: 98
view all 31 authors...
Abstract Background/purpose This sub-analysis of the prospective Low Risk TAVR (LRT) trial determined anatomical characteristics associated with hypoattenuated leaflet thickening (HALT), which may contribute to early transcatheter heart valve (THV) degeneration. Methods/materials The LRT trial enrolled 200 low-risk patients between February 2016 and February 2018. All subjects underwent baseline and 30-day CT studies, analyzed by an independent core laboratory. Additional measurements, namely TH...
Source
#1Puja B. Parikh (SBU: Stony Brook University)H-Index: 15
Last. Robert PyoH-Index: 12
view all 5 authors...
BACKGROUND The use of balloon aortic valvuloplasty (BAV) prior to same-setting complex percutaneous coronary intervention (PCI) in patients with severe aortic stenosis (AS) and concomitant severe coronary artery disease (CAD) has not been well studied in the era of transcatheter aortic valve replacement (TAVR). METHODS We reviewed 379 BAVs performed between January 2016 and April 2020 at an academic tertiary-care medical center. Overall, 327 BAVs were performed in the setting of TAVR. Of the rem...
#1Puja B. Parikh (SBU: Stony Brook University)H-Index: 15
#2Deepak L. Bhatt (Brigham and Women's Hospital)H-Index: 167
Last. Javed Butler (University of Mississippi)H-Index: 99
view all 11 authors...
Abstract Coronary artery disease (CAD) is highly prevalent in patients with heart failure (HF) and accounts for nearly two-thirds of cases. The use of percutaneous coronary intervention (PCI) in HF patients with CAD has markedly increased and has been suggested to be associated with improved outcomes in numerous observational studies. Randomized data comparing the impact of PCI with that of coronary artery bypass graft (CABG) or contemporary guideline-directed medical therapy alone on clinical o...
Source
Source
#1Giorgio A. Medranda (MedStar Washington Hospital Center)H-Index: 2
#1Giorgio A. Medranda (MedStar Washington Hospital Center)H-Index: 2
Last. Ron Waksman (MedStar Washington Hospital Center)H-Index: 98
view all 29 authors...
Abstract Background Prospective bicuspid low-risk transcatheter aortic valve replacement (TAVR) registries' data demonstrated encouraging short-term results. Detailed data on transcatheter heart valve (THV) geometry after deployment using contemporary devices are lacking. This study sought to examine valve geometry after TAVR in patients with bicuspid aortic stenosis (AS). Methods The study populations were patients from the LRT (Low Risk TAVR) trial who underwent TAVR using the SAPIEN 3 THV for...
Source
#1Brandon Kovarovic (SBU: Stony Brook University)H-Index: 4
#2Oren M. Rotman (SBU: Stony Brook University)H-Index: 7
Last. Danny Bluestein (SBU: Stony Brook University)H-Index: 41
view all 5 authors...
Following in vitro tests established for surgical prosthetic heart valves, transcatheter aortic valves (TAV) are similarly tested in idealized geometries-excluding effects that may hamper TAVR performance in situ. Testing in vitro in pulse duplicator systems that incorporated patient-specific replicas would enhance the testing veracity by bringing it closer to the clinical scenario. To that end we compare TAV hemodynamic performance tested in idealized geometries according to the ISO standard (b...
Source
#1Ron Waksman (MedStar Washington Hospital Center)H-Index: 98
#2Rebecca Torguson (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 56
Last. Toby Rogers (MedStar Washington Hospital Center)H-Index: 13
view all 23 authors...
Abstract Background Previous studies from the Low Risk TAVR (LRT) trial demonstrated that transcatheter aortic valve replacement (TAVR) is safe and feasible in low-risk patients, with excellent 30-day and 1-year outcomes. The objective of this study was to report clinical outcomes and the impact of 30-day hypoattenuated leaflet thickening (HALT) on structural valve deterioration (SVD) 2 years after TAVR. Methods The LRT trial was the first Food and Drug Administration-approved Investigational De...
Source