Barry J. Maron
Tufts Medical Center
Internal medicineSurgeryCardiologyMuscle hypertrophyPhysical therapyPediatricsSudden cardiac deathLeft ventricular hypertrophyMitral valveHeart failureCardiomyopathyDiseaseElectrocardiographyHeart diseaseHypertrophic cardiomyopathyAthletesPopulationSudden deathIn patientMedicine
Publications 860
#1Ethan J. Rowin (Tufts Medical Center)H-Index: 26
#2Barry J. Maron (Tufts Medical Center)H-Index: 169
Last. Martin S. Maron (Tufts Medical Center)H-Index: 70
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While predicting prognosis to anticipate adverse disease course has long been an aspiration in hypertrophic cardiomyopathy (HC), reliable markers of progressive and unrelenting heart failure symptoms in the absence of obstruction are not well characterized. We sought to evaluate markers of systolic function, including the role of global longitudinal strain (GLS), to identify nonobstructive HC patients at risk for future heart failure. A cohort of 296 consecutive nonobstructive HC patients (42 ± ...
#1James E. Udelson (Tufts Medical Center)H-Index: 99
#2Ethan J. Rowin (Tufts Medical Center)H-Index: 26
Last. Barry J. Maron (Tufts Medical Center)H-Index: 169
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1 CitationsSource
#1Manhal Habib (UHN: University Health Network)H-Index: 2
#2Arnon Adler (UHN: University Health Network)H-Index: 16
Last. Raymond H. Chan (UHN: University Health Network)H-Index: 19
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OBJECTIVES This study examined fibrosis progression in hypertrophic cardiomyopathy (HCM) patients, as well as its relationship to patient characteristics, clinical outcomes, and its effect on clinical decision making. BACKGROUND Myocardial fibrosis, as quantified by late gadolinium enhancement (LGE) in cardiac magnetic resonance (CMR), provides valuable prognostic information in patients with HCM. METHODS A total of 157 patients with HCM were enrolled in this study, with 2 sequential CMR scans s...
3 CitationsSource
#1Christos A. Papanastasiou (AHEPA University Hospital)H-Index: 5
#2Thomas Zegkos (AHEPA University Hospital)H-Index: 7
Last. Georgios K. Efthimiadis (AHEPA University Hospital)H-Index: 15
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Abstract Objectives The aim of this study was to systematically review and quantitatively synthesize existing evidence about the prognostic value of LV apical aneurysm in patients with HCM. Background Hypertrophic cardiomyopathy (HCM) represents a common inherited heart disease associated with enormous diversity in morphologic expression and clinical course. With the increasing penetration of advanced high resolution cardiovascular imaging into routine HCM practice, a subset of HCM patients with...
1 CitationsSource
#1Kevin M. Harris (Abbott Northwestern Hospital)H-Index: 32
Last. Barry J. Maron (Tufts Medical Center)H-Index: 169
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ABSTRACT Sudden deaths in young active people and athletes are distinctly uncommon and frequently related to highly visible cardiovascular conditions including hypertrophic cardiomyopathy and congenital coronary anomalies. Myocarditis is also a cause of sudden death in the young, but frequently under-recognized clinically, and therefore deserving of the present analysis. Two large registries were interrogated for cases of myocarditis, and clinical, demographic and pathologic findings were assess...
#1Jamshid Shirani (St. Luke's University Health Network)
#1Jamshid Shirani (St. Luke's University Health Network)H-Index: 29
Last. Barry J. Maron (St. Luke's University Health Network)H-Index: 169
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Major advances in diagnosis and treatment have emerged for hypertrophic cardiomyopathy (HCM), largely in major tertiary referral centers dedicated to this disease. Whether these therapeutic benefits are confined to patients in such highly selected cohorts, or can be implemented effectively in independent regional or community-based populations is not generally appreciated. We assessed management and clinical outcomes in a non-referral HCM center (n = 214 patients) in Eastern Pennsylvania. Over a...
#1Barry J. MaronH-Index: 169
#2Ethan J. RowinH-Index: 26
Last. Martin S. MaronH-Index: 70
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2 CitationsSource
#1Bradley A. Maron (Brigham and Women's Hospital)H-Index: 32
#2Rui-Sheng Wang (Brigham and Women's Hospital)H-Index: 29
Last. Joseph Loscalzo (Brigham and Women's Hospital)H-Index: 148
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Progress in precision medicine is limited by insufficient knowledge of transcriptomic or proteomic features in involved tissues that define pathobiological differences between patients. Here, myectomy tissue from patients with obstructive hypertrophic cardiomyopathy and heart failure is analyzed using RNA-Seq, and the results are used to develop individualized protein-protein interaction networks. From this approach, hypertrophic cardiomyopathy is distinguished from dilated cardiomyopathy based ...