Vera Triunfante
University of Minho
EpidemiologyDrug resistanceGenotypeViral loadDemographyReverse transcriptaseVirologyHuman leukocyte antigenViral phylodynamicsTransmission (medicine)TenofovirZidovudineHuman immunodeficiency virus (HIV)PortugueseGenetic variationMedicineBiologyPhylogeneticsMolecular epidemiology
Publications 2
The success of antiretroviral treatment (ART) is threatened by the emergence of drug resistance mutations (DRM). Since Brazil presents the largest number of people living with HIV (PLWH) in South America we aimed at understanding the dynamics of DRM in this country. We analyzed a total of 20,226 HIV-1 sequences collected from PLWH undergoing ART between 2008–2017. Results show a mild decline of DRM over the years but an increase of the K65R reverse transcriptase mutation from 2.23% to 12.11%. Th...
#1Alexandre Antonio de Carvalho (RMIT: RMIT University)H-Index: 4
#2Patrício Costa (RMIT: RMIT University)H-Index: 32
Last. Nuno S. Osório (RMIT: RMIT University)H-Index: 15
view all 12 authors...
The existing data support Portugal as the western European country with the highest HIV-1 subtype diversity. However, detailed phylogenetic studies of Portuguese HIV-1 epidemics are still scarce. Thus, our main goal was to analyze the phylodynamics of a local HIV-1 infection in the Portuguese region of Minho. Molecular epidemiological analysis was applied to data from 289 HIV-1-infected individuals followed at the reference hospital of the province of Minho, Portugal, at which isolated viruses h...
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