Kyu Sang Lee
Seoul National University Bundang Hospital
CancerInternal medicineRadiologyPathologyOncologyRetrospective cohort studyCD8ImmunohistochemistryHazard ratioGlioblastomaImmunotherapyMicrosatellite instabilityPD-L1Cancer researchColorectal cancerBreast cancerCarcinogenesisMedicineCohortBiologyImmune system
Publications 51
#1Ji-Eyon Kwon (New Generation University College)
#2So Young Ji (New Generation University College)
Last. Jung Ho Han (New Generation University College)
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#1Kyeong-O Go (Gyeongsang National University)H-Index: 1
#2Minji Lee (SNU: Seoul National University)
Last. Chae-Yong Kim (SNU: Seoul National University)H-Index: 30
view all 6 authors...
Subependymoma is a slow-growing, exophytic, intraventricular glial neoplasm that commonly arises in the ventricular system. However, a report found that the frequency of intracerebral subependymoma was 0.4% in 1000 routine autopsies. To the best of our knowledge, only seven cases of intracerebral subependymoma have been reported. We report a rare case of intracerebral subependymoma in a child. An 11-year-old girl with generalized tonic-clonic seizures visited the emergency room and had an intrap...
#1Bo Ri Kim (Seoul National University Bundang Hospital)H-Index: 11
#2Minsu Kim (Seoul National University Bundang Hospital)H-Index: 1
Last. Sang Woong Youn (Seoul National University Bundang Hospital)H-Index: 32
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The interleukin (IL)-23/T-helper (Th)17 axis is considered central to the pathogenesis of psoriasis, with IL-36γ considered a marker for histological differential diagnosis. However, expression data regarding key cytokines in the pathogenesis of psoriasis, as well as data on the effects of IL-23 inhibition on downstream cytokines in human psoriatic skin, are limited. We investigated the expression profile of key cytokines and the effect of ustekinumab (UST) on cytokine expression in human psoria...
#1Kyu Sang Lee (New Generation University College)H-Index: 13
#2Gheeyoung Choe (New Generation University College)H-Index: 31
Programmed cell death protein 1/programmed death-ligand 1 (PD-1/PD-L1) inhibition has revolutionized the treatment paradigm of urothelial carcinoma (UC). Several PD-L1 assays are conducted to formulate appropriate treatment decisions for PD-1/PD-L1 target therapy in UC. However, each assay has its own specific requirement of antibody clones, staining platforms, scoring algorithms, and cutoffs for the determination of PD-L1 status. These prove to be challenging constraints to pathology laboratori...
#1Yunsook Kang (Seoul National University Hospital)
#2Yoo Jung Kim (Seoul National University Hospital)H-Index: 1
Last. Jinwook Choi (SNU: Seoul National University)H-Index: 15
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Background Artificial intelligence (AI) research is highly dependent on the nature of the data available. With the steady increase of AI applications in the medical field, the demand for quality medical data is increasing significantly. We here describe the development of a platform for providing and sharing digital pathology data to AI researchers, and highlight challenges to overcome in operating a sustainable platform in conjunction with pathologists. Methods Over 3000 pathological slides fro...
#1Quanjun Cui (UVA: University of Virginia)H-Index: 34
#2Woo Lam Jo (Catholic University of Korea)H-Index: 6
Last. Dewei Zhao (DUT: Dalian University of Technology)H-Index: 21
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Osteonecrosis of the femoral head (ONFH) is a devastating disease frequently leading to femoral head collapse and hip arthritis. Specifically, non-traumatic ONFH primarily affects young and middle-aged adults. Although compromised local circulation of the femoral head seems to be pathognomonic for the disease, the pathogenesis is perplexing and continues to be an area of scrutiny and research. Comprehension of the pathogenesis is of crucial importance for developing and guiding treatments for th...
#1Mi-Kyung Um (Kangwon National University)
#2Eugene Lee (Seoul National University Bundang Hospital)H-Index: 10
Last. Heung Sik Kang (Seoul National University Bundang Hospital)H-Index: 28
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#1Hee Young Na (Seoul National University Bundang Hospital)H-Index: 4
#2Yujun Park (Seoul National University Bundang Hospital)H-Index: 4
Last. Hye Seung Lee (Seoul National University Hospital)H-Index: 67
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Downregulation of human leukocyte antigen (HLA) class I has been postulated to be a mechanism of adaptive immune escape in various tumors, especially microsatellite instability-high (MSI-H) colorectal cancer (CRC). In this study, we aimed to investigate HLA class I and β2-microglobulin (β2M) expression in MSI-H and microsatellite-stable (MSS) CRCs and determine its prognostic impact. The representative areas from the tumor center (TC) and tumor periphery (TP) from 300 CRCs, including 161 MSI-H a...
1 CitationsSource
#1Hyungmin Ahn (Seoul National University Bundang Hospital)
#2Kyu Sang Lee (Seoul National University Bundang Hospital)H-Index: 13
Last. Gheeyoung Choe (Seoul National University Bundang Hospital)H-Index: 31
view all 3 authors...